Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

Gene Info

Gene Information For:Hs. HGS, Hepatocyte growth factor-regulated tyrosine kinase substrate
Sequence ID:NM_004712
Entrez Gene ID:9146
Ensembl ID:ENSG00000185359

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaSNPSNP: GeneViewSNP: VarViewAssembliesCancer AberrationsRNAi

Gene Expression Data

  • This gene is found in these cDNA libraries from the following tissue types:
    b-cell, bone, brain, cartilage, cerebellum, cerebrum, cervix, colon, embryonic tissue, endocrine, eye, fetus, gastrointestinal tract, heart, kidney, liver, lung, lymph node, lymphoreticular, mammary gland, muscle, nervous, ovary, pancreas, pancreatic islet, peripheral nervous system, pituitary gland, placenta, pooled tissue, prostate, retina, salivary gland, skin, spleen, stem cell, stomach, t-cell, testis, thymus, thyroid, uncharacterized tissue, uterus
  • SAGE Anatomic Viewer
  • SAGE Digital Northern

  • Monochromatic SAGE/cDNA Virtual Northern

  • Two-dimensional array displays (similar expression pattern in NCI60 microarray data or SAGE data)

Cytogenetic Location (from UniGene)

Cytogenetic Location:17q25Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:17: 79651092 - 79669147

 Exon Info From UCSC:

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3544197Full LengthBC003565hepatocyte growth factor-regulated tyrosine kinase substrate

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_004703  

Protein Infomation

NM_004712 NP_004703 O14964 VHS

Related Sequences

U43895 AAC51929 O14964
AF260566 AAF82361 O14964
BC003565 AAH03565 O14964
BT009754 AAP88756 O14964
DQ892551 ABM83477  
DQ895762 ABM86688  
D84064 BAA23366 O14964
AK294190 BAG57506 B4DFP5
AK303800 BAG64754 B4E1E2

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene Info Protein
H.sapiens HGS NP_004703 M.musculus Hgs 15239 Gene Info NP_001152800 94
R.norvegicus Hgs 56084   NP_062260 94
A.gambiae AgaP_AGAP008887 1279855   XP_319634 48
D.melanogaster Hrs 33458   NP_525099 47
C.elegans hgrs-1 177617   NP_501375 37

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta