Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Genes
  • Gene Tools
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.


Gene Info

Gene Information For:Hs. CASP2, Caspase 2, apoptosis-related cysteine peptidase
Sequence ID:NM_032982
NM_001224
NM_032983
RefSeqGene ID:NG_029248
Entrez Gene ID:835
Ensembl ID:ENSG00000106144

Database Links

UniGeneEntrez GeneOMIMEnsembl GeneHPRDVegaDTPSNPSNP: GeneViewSNP: VarViewAssembliesRNAi

Gene Expression Data


Cytogenetic Location (from UniGene)

Cytogenetic Location:7q34-q35Mitelman Breakpoint Data

Chromosomal Position (from UCSC)

Chromosomal Position:7: 142985599 - 143002164

 Exon Info From UCSC:
NM_032982
NM_032983

Full-Length MGC Clones for This Gene

IMAGE IdStatusAccession GenBank Def Line
3346279Full LengthBC002427caspase 2, apoptosis-related cysteine peptidase

Protein Similarities Based on Shared Motif Content

Find gene products sharing protein motifs with:  NP_116764  NP_116765  

Protein Infomation

RefSeq
mRNAProteinSwissProtEnzymePfam
NM_001224 NP_001215      
NM_032982 NP_116764 P42575 EC 3.4.22.55 CARD
Peptidase_C14
NM_032983 NP_116765     CARD

Related Sequences

 
mRNAGenPeptSwissProtEnzyme
U13021 AAA58959 P42575 EC 3.4.22.55
U13022 AAA58960 P42575 EC 3.4.22.55
BC002427 AAH02427 P42575 EC 3.4.22.55
AF314174 AAK00299 Q9BZL0  
AF314175 AAK00300 P42575 EC 3.4.22.55
BT007240 AAP35904 P42575 EC 3.4.22.55
DQ893820 ABM84746    
AB209640 BAD92877 P42575 EC 3.4.22.55
AK291274 BAF83963 P42575 EC 3.4.22.55
AK303265 BAG64347 B4E085  
AK303391 BAG64447 B4E0I5  
CR541748 CAG46548 P42575 EC 3.4.22.55

Homologs (from HomoloGene)
Note: Both orthologs and paralogs are included.
Organism Symbol Protein Homolog Similarity
(% aa unchanged)
Organism Symbol Entrez
Gene
Gene Info Protein
H.sapiens CASP2 NP_116764 M.musculus Casp2 12366 Gene Info NP_031636 90
R.norvegicus Casp2 64314   NP_071967 90
C.elegans ced-3 178272   NP_502538 36

Gene Ontology
Gene classification by the European Bioinformatics Institute, as recorded in GOA (GO Annotation@EBI)

BioCarta Pathways
Pathway information courtesy of BioCarta