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Chromosomes
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The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
18p11 del(18)(p11) Malignant melanoma Eye  
18p11 der(18)t(6;18)(p12;p11) Malignant melanoma Eye  
18q23 add(18)(q23) Malignant melanoma Eye  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+2 Malignant melanoma Eye  
+4 Malignant melanoma Eye  
+5 Malignant melanoma Eye  
+6 Malignant melanoma Eye 13   
+7 Malignant melanoma Eye 14   
+8 Malignant melanoma Eye 39   
+9 Malignant melanoma Eye  
+10 Malignant melanoma Eye  
+11 Malignant melanoma Eye  
+12 Malignant melanoma Eye  
+13 Malignant melanoma Eye  
+14 Malignant melanoma Eye  
+15 Malignant melanoma Eye  
+16 Malignant melanoma Eye  
+17 Malignant melanoma Eye  
+18 Malignant melanoma Eye  
+19 Malignant melanoma Eye  
+20 Malignant melanoma Eye  
+21 Malignant melanoma Eye 15   
+22 Malignant melanoma Eye 15   

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Malignant melanoma Eye 14   
-2 Malignant melanoma Eye  
-3 Malignant melanoma Eye 67   
-4 Malignant melanoma Eye  
-5 Malignant melanoma Eye  
-6 Malignant melanoma Eye  
-7 Malignant melanoma Eye  
-8 Malignant melanoma Eye  
-9 Malignant melanoma Eye  
-10 Malignant melanoma Eye  
-11 Malignant melanoma Eye  
-12 Malignant melanoma Eye  
-13 Malignant melanoma Eye  
-14 Malignant melanoma Eye  
-15 Malignant melanoma Eye 23   
-16 Malignant melanoma Eye 19   
-17 Malignant melanoma Eye 10   
-18 Malignant melanoma Eye  
-19 Malignant melanoma Eye  
-20 Malignant melanoma Eye  
-21 Malignant melanoma Eye  
-22 Malignant melanoma Eye  
-X Malignant melanoma Eye 25   
-Y Malignant melanoma Eye 47