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The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
18q21 t(11;18)(q21;q21) Extranodal marginal zone B-cell lymphoma Large intestine MALT1+
18q21 t(11;18)(q21;q21) Extranodal marginal zone B-cell lymphoma Stomach 10  MALT1+
18q21 t(11;18)(q21;q21) Extranodal marginal zone B-cell lymphoma Lung MALT1+
18q21 t(11;18)(q21;q21) Extranodal marginal zone B-cell lymphoma Unknown site  
18q21 t(14;18)(q32;q21) Extranodal marginal zone B-cell lymphoma Eye IGH/MALT1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
18p11 add(18)(p11) Extranodal marginal zone B-cell lymphoma Stomach  
18q10 i(18)(q10) Extranodal marginal zone B-cell lymphoma Salivary gland  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+3 Extranodal marginal zone B-cell lymphoma    
+3 Extranodal marginal zone B-cell lymphoma Stomach  
+3 Extranodal marginal zone B-cell lymphoma Eye  
+3 Extranodal marginal zone B-cell lymphoma Thyroid  
+3 Extranodal marginal zone B-cell lymphoma Breast  
+3 Extranodal marginal zone B-cell lymphoma Unknown site  
+3 Extranodal marginal zone B-cell lymphoma Lung  
+3 Extranodal marginal zone B-cell lymphoma Salivary gland  
+4 Extranodal marginal zone B-cell lymphoma Salivary gland  
+5 Extranodal marginal zone B-cell lymphoma Stomach  
+7 Extranodal marginal zone B-cell lymphoma Salivary gland  
+7 Extranodal marginal zone B-cell lymphoma Eye  
+10 Extranodal marginal zone B-cell lymphoma Eye  
+12 Extranodal marginal zone B-cell lymphoma Lung  
+12 Extranodal marginal zone B-cell lymphoma    
+12 Extranodal marginal zone B-cell lymphoma Skin  
+12 Extranodal marginal zone B-cell lymphoma Stomach  
+18 Extranodal marginal zone B-cell lymphoma Unknown site  
+18 Extranodal marginal zone B-cell lymphoma Eye  
+18 Extranodal marginal zone B-cell lymphoma Breast  
+18 Extranodal marginal zone B-cell lymphoma Stomach  
+18 Extranodal marginal zone B-cell lymphoma Salivary gland  
+18 Extranodal marginal zone B-cell lymphoma    
+18 Extranodal marginal zone B-cell lymphoma Lung  
+X Extranodal marginal zone B-cell lymphoma Salivary gland  

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-6 Extranodal marginal zone B-cell lymphoma Salivary gland  
-6 Extranodal marginal zone B-cell lymphoma Stomach  
-6 Extranodal marginal zone B-cell lymphoma Thyroid  
-7 Extranodal marginal zone B-cell lymphoma Small intestine  
-9 Extranodal marginal zone B-cell lymphoma Stomach  
-9 Extranodal marginal zone B-cell lymphoma Small intestine  
-14 Extranodal marginal zone B-cell lymphoma Small intestine  
-20 Extranodal marginal zone B-cell lymphoma Thyroid  
-21 Extranodal marginal zone B-cell lymphoma Eye  
-21 Extranodal marginal zone B-cell lymphoma Unknown site  
-X Extranodal marginal zone B-cell lymphoma Stomach  
-X Extranodal marginal zone B-cell lymphoma Salivary gland