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The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
18p11 t(13;18)(q14;p11) Chronic lymphocytic leukemia    
18q21 t(11;18)(q21;q21) Chronic lymphocytic leukemia    
18q21 t(14;18)(q32;q21) Chronic lymphocytic leukemia   105  IGH/BCL2
18q21 t(18;22)(q21;q11) Chronic lymphocytic leukemia   23  IGL/BCL2
18q21 t(2;18)(p11;q21) Chronic lymphocytic leukemia   IGK/BCL2
18q21 t(2;18)(p12;q21) Chronic lymphocytic leukemia   BCL2+
18q22 t(14;18)(q32;q22) Chronic lymphocytic leukemia    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
18p11 add(18)(p11) Chronic lymphocytic leukemia   11   
18p11 der(18)t(2;18)(p11;p11) Chronic lymphocytic leukemia    
18p11 dic(17;18)(p11;p11) Chronic lymphocytic leukemia    
18p11 dic(2;18)(q11;p11) Chronic lymphocytic leukemia    
18q10 der(17;18)(q10;q10) Chronic lymphocytic leukemia   18   
18q11 der(20)t(18;20)(q11;p11) Chronic lymphocytic leukemia    
18q21 del(18)(q21) Chronic lymphocytic leukemia    
18q21 der(14)t(14;18)(q32;q21) Chronic lymphocytic leukemia    
18q21 der(18)t(14;18)(q32;q21) Chronic lymphocytic leukemia    
18q22 del(18)(q22) Chronic lymphocytic leukemia    
18q23 add(18)(q23) Chronic lymphocytic leukemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Chronic lymphocytic leukemia   13   
+2 Chronic lymphocytic leukemia    
+3 Chronic lymphocytic leukemia   50   
+4 Chronic lymphocytic leukemia   10   
+5 Chronic lymphocytic leukemia   13   
+6 Chronic lymphocytic leukemia   13   
+7 Chronic lymphocytic leukemia   23   
+8 Chronic lymphocytic leukemia   37   
+9 Chronic lymphocytic leukemia   16   
+10 Chronic lymphocytic leukemia    
+11 Chronic lymphocytic leukemia    
+12 Chronic lymphocytic leukemia   780   
+13 Chronic lymphocytic leukemia   10   
+14 Chronic lymphocytic leukemia    
+15 Chronic lymphocytic leukemia   17   
+16 Chronic lymphocytic leukemia   11   
+17 Chronic lymphocytic leukemia   12   
+18 Chronic lymphocytic leukemia   86   
+19 Chronic lymphocytic leukemia   67   
+20 Chronic lymphocytic leukemia   14   
+21 Chronic lymphocytic leukemia   38   
+22 Chronic lymphocytic leukemia   19   
+X Chronic lymphocytic leukemia   32   
+Y Chronic lymphocytic leukemia   13   

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Chronic lymphocytic leukemia   20   
-2 Chronic lymphocytic leukemia   26   
-3 Chronic lymphocytic leukemia   27   
-4 Chronic lymphocytic leukemia   26   
-5 Chronic lymphocytic leukemia   26   
-6 Chronic lymphocytic leukemia   37   
-7 Chronic lymphocytic leukemia   26   
-8 Chronic lymphocytic leukemia   65   
-9 Chronic lymphocytic leukemia   51   
-10 Chronic lymphocytic leukemia   37   
-11 Chronic lymphocytic leukemia   38   
-12 Chronic lymphocytic leukemia   24   
-13 Chronic lymphocytic leukemia   73   
-14 Chronic lymphocytic leukemia   46   
-15 Chronic lymphocytic leukemia   41   
-16 Chronic lymphocytic leukemia   23   
-17 Chronic lymphocytic leukemia   105   
-18 Chronic lymphocytic leukemia   57   
-19 Chronic lymphocytic leukemia   13   
-20 Chronic lymphocytic leukemia   44   
-21 Chronic lymphocytic leukemia   48   
-22 Chronic lymphocytic leukemia   37   
-X Chronic lymphocytic leukemia   99   
-Y Chronic lymphocytic leukemia   129