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The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
18q11 t(14;18)(q32;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q11 t(18;20)(q11;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q12 t(12;18)(p12;q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q21 t(14;18)(q32;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma   47  BCL2/IGHG1,IGH/BCL2

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
18p11 add(18)(p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma   10   
18p11 del(18)(p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18p11 dic(12;18)(p11;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18p11 dic(16;18)(q11;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18p11 dic(9;18)(p13;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q10 der(18;21)(q10;q10) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q10 i(18)(q10) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q11 der(12)t(12;18)(p11;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q11 der(9)t(9;18)(p13;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q12 add(18)(q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q12 del(18)(q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q21 add(18)(q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma   10   
18q21 del(18)(q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma   10   
18q21 der(14)t(14;18)(q32;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q21 der(8)t(8;14)(q24;q32)t(14;18)(q32;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
18q23 add(18)(q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   12   

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Acute lymphoblastic leukemia/lymphoblastic lymphoma   149   
+2 Acute lymphoblastic leukemia/lymphoblastic lymphoma   140   
+3 Acute lymphoblastic leukemia/lymphoblastic lymphoma   79   
+4 Acute lymphoblastic leukemia/lymphoblastic lymphoma   952   
+5 Acute lymphoblastic leukemia/lymphoblastic lymphoma   401   
+6 Acute lymphoblastic leukemia/lymphoblastic lymphoma   1096   
+7 Acute lymphoblastic leukemia/lymphoblastic lymphoma   170   
+8 Acute lymphoblastic leukemia/lymphoblastic lymphoma   933   
+9 Acute lymphoblastic leukemia/lymphoblastic lymphoma   285   
+10 Acute lymphoblastic leukemia/lymphoblastic lymphoma   1011   
+11 Acute lymphoblastic leukemia/lymphoblastic lymphoma   249   
+12 Acute lymphoblastic leukemia/lymphoblastic lymphoma   201   
+13 Acute lymphoblastic leukemia/lymphoblastic lymphoma   206   
+14 Acute lymphoblastic leukemia/lymphoblastic lymphoma   1099   
+15 Acute lymphoblastic leukemia/lymphoblastic lymphoma   184   
+16 Acute lymphoblastic leukemia/lymphoblastic lymphoma   162   
+17 Acute lymphoblastic leukemia/lymphoblastic lymphoma   785   
+18 Acute lymphoblastic leukemia/lymphoblastic lymphoma   1009   
+19 Acute lymphoblastic leukemia/lymphoblastic lymphoma   284   
+20 Acute lymphoblastic leukemia/lymphoblastic lymphoma   217   
+21 Acute lymphoblastic leukemia/lymphoblastic lymphoma   2169   
+22 Acute lymphoblastic leukemia/lymphoblastic lymphoma   409   
+X Acute lymphoblastic leukemia/lymphoblastic lymphoma   1535   
+Y Acute lymphoblastic leukemia/lymphoblastic lymphoma   251   

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Acute lymphoblastic leukemia/lymphoblastic lymphoma   263   
-2 Acute lymphoblastic leukemia/lymphoblastic lymphoma   319   
-3 Acute lymphoblastic leukemia/lymphoblastic lymphoma   408   
-4 Acute lymphoblastic leukemia/lymphoblastic lymphoma   238   
-5 Acute lymphoblastic leukemia/lymphoblastic lymphoma   222   
-6 Acute lymphoblastic leukemia/lymphoblastic lymphoma   127   
-7 Acute lymphoblastic leukemia/lymphoblastic lymphoma   658   
-8 Acute lymphoblastic leukemia/lymphoblastic lymphoma   249   
-9 Acute lymphoblastic leukemia/lymphoblastic lymphoma   495   
-10 Acute lymphoblastic leukemia/lymphoblastic lymphoma   186   
-11 Acute lymphoblastic leukemia/lymphoblastic lymphoma   240   
-12 Acute lymphoblastic leukemia/lymphoblastic lymphoma   332   
-13 Acute lymphoblastic leukemia/lymphoblastic lymphoma   490   
-14 Acute lymphoblastic leukemia/lymphoblastic lymphoma   224   
-15 Acute lymphoblastic leukemia/lymphoblastic lymphoma   439   
-16 Acute lymphoblastic leukemia/lymphoblastic lymphoma   396   
-17 Acute lymphoblastic leukemia/lymphoblastic lymphoma   352   
-18 Acute lymphoblastic leukemia/lymphoblastic lymphoma   184   
-19 Acute lymphoblastic leukemia/lymphoblastic lymphoma   305   
-20 Acute lymphoblastic leukemia/lymphoblastic lymphoma   459   
-21 Acute lymphoblastic leukemia/lymphoblastic lymphoma   255   
-22 Acute lymphoblastic leukemia/lymphoblastic lymphoma   253   
-X Acute lymphoblastic leukemia/lymphoblastic lymphoma   291   
-Y Acute lymphoblastic leukemia/lymphoblastic lymphoma   218