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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p11 t(11;14)(p11;q32) Splenic marginal zone B-cell lymphoma   IGH+
11q13 t(11;14)(q13;q32) Splenic marginal zone B-cell lymphoma   15  CCND1+

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q13 del(11)(q13q23) Splenic marginal zone B-cell lymphoma    
11q21 del(11)(q21) Splenic marginal zone B-cell lymphoma    
11q23 del(11)(q13q23) Splenic marginal zone B-cell lymphoma    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Splenic marginal zone B-cell lymphoma    
+3 Splenic marginal zone B-cell lymphoma   29   
+4 Splenic marginal zone B-cell lymphoma    
+5 Splenic marginal zone B-cell lymphoma    
+7 Splenic marginal zone B-cell lymphoma    
+8 Splenic marginal zone B-cell lymphoma    
+9 Splenic marginal zone B-cell lymphoma    
+10 Splenic marginal zone B-cell lymphoma    
+11 Splenic marginal zone B-cell lymphoma    
+12 Splenic marginal zone B-cell lymphoma   18   
+13 Splenic marginal zone B-cell lymphoma    
+18 Splenic marginal zone B-cell lymphoma   27   
+19 Splenic marginal zone B-cell lymphoma    
+22 Splenic marginal zone B-cell lymphoma    
+X Splenic marginal zone B-cell lymphoma   16   

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Splenic marginal zone B-cell lymphoma    
-2 Splenic marginal zone B-cell lymphoma    
-4 Splenic marginal zone B-cell lymphoma    
-5 Splenic marginal zone B-cell lymphoma    
-6 Splenic marginal zone B-cell lymphoma    
-7 Splenic marginal zone B-cell lymphoma    
-8 Splenic marginal zone B-cell lymphoma    
-9 Splenic marginal zone B-cell lymphoma    
-10 Splenic marginal zone B-cell lymphoma    
-11 Splenic marginal zone B-cell lymphoma    
-12 Splenic marginal zone B-cell lymphoma    
-13 Splenic marginal zone B-cell lymphoma    
-14 Splenic marginal zone B-cell lymphoma    
-15 Splenic marginal zone B-cell lymphoma    
-16 Splenic marginal zone B-cell lymphoma    
-17 Splenic marginal zone B-cell lymphoma    
-18 Splenic marginal zone B-cell lymphoma    
-19 Splenic marginal zone B-cell lymphoma    
-20 Splenic marginal zone B-cell lymphoma    
-21 Splenic marginal zone B-cell lymphoma   12   
-22 Splenic marginal zone B-cell lymphoma    
-X Splenic marginal zone B-cell lymphoma    
-Y Splenic marginal zone B-cell lymphoma   11