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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q13 t(11;14)(q13;q24) Mantle cell lymphoma    
11q13 t(11;14)(q13;q32) Mantle cell lymphoma   466  IGH/CCND1
11q13 t(8;11)(q24;q13) Mantle cell lymphoma    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p11 del(11)(p11) Mantle cell lymphoma    
11p11 der(9)t(9;11)(q11;p11) Mantle cell lymphoma    
11p15 add(11)(p15) Mantle cell lymphoma    
11q13 add(11)(q13) Mantle cell lymphoma    
11q13 del(11)(q13) Mantle cell lymphoma   CCND1+
11q13 der(11)t(11;14)(q13;q32) Mantle cell lymphoma   28   
11q13 der(14)t(11;14)(q13;q32) Mantle cell lymphoma   25   
11q13 der(16)t(11;16)(q13;q24) Mantle cell lymphoma    
11q13 der(9)t(9;11)(q34;q13) Mantle cell lymphoma    
11q13 dup(11)(q13q23) Mantle cell lymphoma    
11q13 dup(11)(q13q25) Mantle cell lymphoma    
11q21 del(11)(q21q23) Mantle cell lymphoma    
11q21 der(14)t(11;14)del(11)(q21q23) Mantle cell lymphoma    
11q22 add(11)(q22) Mantle cell lymphoma    
11q23 del(11)(q21q23) Mantle cell lymphoma    
11q23 del(11)(q23) Mantle cell lymphoma    
11q23 der(14)t(11;14)del(11)(q21q23) Mantle cell lymphoma    
11q23 dup(11)(q13q23) Mantle cell lymphoma    
11q25 add(11)(q25) Mantle cell lymphoma    
11q25 dup(11)(q13q25) Mantle cell lymphoma    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+2 Mantle cell lymphoma    
+3 Mantle cell lymphoma   40   
+4 Mantle cell lymphoma    
+5 Mantle cell lymphoma    
+6 Mantle cell lymphoma    
+7 Mantle cell lymphoma   15   
+8 Mantle cell lymphoma   10   
+9 Mantle cell lymphoma    
+10 Mantle cell lymphoma    
+11 Mantle cell lymphoma    
+12 Mantle cell lymphoma   20   
+13 Mantle cell lymphoma    
+14 Mantle cell lymphoma    
+15 Mantle cell lymphoma    
+16 Mantle cell lymphoma    
+17 Mantle cell lymphoma    
+18 Mantle cell lymphoma   16   
+19 Mantle cell lymphoma    
+20 Mantle cell lymphoma    
+21 Mantle cell lymphoma   11   
+22 Mantle cell lymphoma    
+X Mantle cell lymphoma    
+Y Mantle cell lymphoma    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Mantle cell lymphoma   24   
-2 Mantle cell lymphoma   17   
-3 Mantle cell lymphoma    
-4 Mantle cell lymphoma   22   
-5 Mantle cell lymphoma   18   
-6 Mantle cell lymphoma   24   
-7 Mantle cell lymphoma   12   
-8 Mantle cell lymphoma   45   
-9 Mantle cell lymphoma   58   
-10 Mantle cell lymphoma   38   
-11 Mantle cell lymphoma   30   
-12 Mantle cell lymphoma   27   
-13 Mantle cell lymphoma   92   
-14 Mantle cell lymphoma   36   
-15 Mantle cell lymphoma   50   
-16 Mantle cell lymphoma   18   
-17 Mantle cell lymphoma   46   
-18 Mantle cell lymphoma   24   
-19 Mantle cell lymphoma   14   
-20 Mantle cell lymphoma   27   
-21 Mantle cell lymphoma   38   
-22 Mantle cell lymphoma   43   
-X Mantle cell lymphoma   38   
-Y Mantle cell lymphoma   59