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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q13 t(11;14)(q13;q32) Plasma cell leukemia   24  IGH/CCND1,IGH+
11q23 t(11;14)(q23;q32) Plasma cell leukemia    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p15 add(11)(p15) Plasma cell leukemia    
11q13 del(11)(q13) Plasma cell leukemia    
11q13 der(11)t(11;14)(q13;q32) Plasma cell leukemia    
11q13 der(14)t(11;14)(q13;q32) Plasma cell leukemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Plasma cell leukemia    
+2 Plasma cell leukemia    
+3 Plasma cell leukemia   16   
+4 Plasma cell leukemia    
+5 Plasma cell leukemia    
+6 Plasma cell leukemia    
+7 Plasma cell leukemia   15   
+8 Plasma cell leukemia    
+9 Plasma cell leukemia   10   
+10 Plasma cell leukemia    
+11 Plasma cell leukemia   13   
+12 Plasma cell leukemia    
+13 Plasma cell leukemia    
+14 Plasma cell leukemia    
+15 Plasma cell leukemia    
+17 Plasma cell leukemia    
+18 Plasma cell leukemia   13   
+19 Plasma cell leukemia   14   
+20 Plasma cell leukemia    
+21 Plasma cell leukemia   18   
+22 Plasma cell leukemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Plasma cell leukemia   17   
-2 Plasma cell leukemia    
-3 Plasma cell leukemia    
-4 Plasma cell leukemia   10   
-5 Plasma cell leukemia   10   
-6 Plasma cell leukemia    
-7 Plasma cell leukemia    
-8 Plasma cell leukemia   27   
-9 Plasma cell leukemia    
-10 Plasma cell leukemia   14   
-11 Plasma cell leukemia   10   
-12 Plasma cell leukemia   10   
-13 Plasma cell leukemia   68   
-14 Plasma cell leukemia   26   
-15 Plasma cell leukemia   18   
-16 Plasma cell leukemia   28   
-17 Plasma cell leukemia   18   
-18 Plasma cell leukemia   18   
-19 Plasma cell leukemia    
-20 Plasma cell leukemia   18   
-21 Plasma cell leukemia   16   
-22 Plasma cell leukemia   23   
-X Plasma cell leukemia   30   
-Y Plasma cell leukemia   17