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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q11 t(11;14)(q11;q32) Multiple myeloma    
11q13 t(11;14)(q13;q32) Multiple myeloma   140  CCND1+,IGH/CCND1
11q13 t(11;17)(q13;p13) Multiple myeloma    
11q23 t(6;11)(q27;q23) Multiple myeloma    
11q23 t(7;11)(q11;q23) Multiple myeloma    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p11 add(11)(p11) Multiple myeloma    
11p11 del(11)(p11) Multiple myeloma    
11p11 del(11)(p11p13) Multiple myeloma    
11p11 del(11)(p11p15) Multiple myeloma    
11p13 add(11)(p13) Multiple myeloma    
11p13 del(11)(p11p13) Multiple myeloma    
11p13 del(11)(p13) Multiple myeloma    
11p14 add(11)(p14) Multiple myeloma    
11p15 add(11)(p15) Multiple myeloma   23   
11p15 del(11)(p11p15) Multiple myeloma    
11p15 del(11)(p15) Multiple myeloma    
11q10 der(11;12)(q10;q10) Multiple myeloma    
11q10 der(11;17)(q10;q10) Multiple myeloma    
11q10 der(11;22)(q10;q10) Multiple myeloma    
11q10 i(11)(q10) Multiple myeloma    
11q11 del(11)(q11) Multiple myeloma    
11q12 del(11)(q12) Multiple myeloma    
11q13 add(11)(q13) Multiple myeloma   10   
11q13 del(11)(q13) Multiple myeloma   14   
11q13 del(11)(q13q21) Multiple myeloma    
11q13 der(11)t(11;14)(q13;q32) Multiple myeloma    
11q13 der(12)t(11;12)(q13;p13) Multiple myeloma    
11q13 der(14)t(11;14)(q13;q32) Multiple myeloma   44   
11q13 der(17)t(11;17)(q13;p11) Multiple myeloma    
11q13 der(19)t(11;19)(q13;p13) Multiple myeloma    
11q13 der(8)t(8;11)(q24;q13) Multiple myeloma    
11q14 del(11)(q14) Multiple myeloma    
11q21 add(11)(q21) Multiple myeloma    
11q21 del(11)(q13q21) Multiple myeloma    
11q21 del(11)(q21) Multiple myeloma    
11q21 del(11)(q21q23) Multiple myeloma    
11q22 add(11)(q22) Multiple myeloma    
11q22 del(11)(q22) Multiple myeloma    
11q22 del(11)(q22q23) Multiple myeloma    
11q23 add(11)(q23) Multiple myeloma   24   
11q23 del(11)(q21q23) Multiple myeloma    
11q23 del(11)(q22q23) Multiple myeloma    
11q23 del(11)(q23) Multiple myeloma   16   
11q23 der(11)t(1;11)(p31;q23) Multiple myeloma    
11q24 add(11)(q24) Multiple myeloma    
11q25 add(11)(q25) Multiple myeloma    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Multiple myeloma   127   
+2 Multiple myeloma   61   
+3 Multiple myeloma   447   
+4 Multiple myeloma   64   
+5 Multiple myeloma   418   
+6 Multiple myeloma   145   
+7 Multiple myeloma   432   
+8 Multiple myeloma   85   
+9 Multiple myeloma   590   
+10 Multiple myeloma   36   
+11 Multiple myeloma   443   
+12 Multiple myeloma   43   
+13 Multiple myeloma   29   
+14 Multiple myeloma   62   
+15 Multiple myeloma   570   
+16 Multiple myeloma   33   
+17 Multiple myeloma   91   
+18 Multiple myeloma   231   
+19 Multiple myeloma   512   
+20 Multiple myeloma   101   
+21 Multiple myeloma   366   
+22 Multiple myeloma   67   
+X Multiple myeloma   26   
+Y Multiple myeloma   36   

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Multiple myeloma   114   
-2 Multiple myeloma   99   
-3 Multiple myeloma   39   
-4 Multiple myeloma   173   
-5 Multiple myeloma   82   
-6 Multiple myeloma   95   
-7 Multiple myeloma   80   
-8 Multiple myeloma   254   
-9 Multiple myeloma   52   
-10 Multiple myeloma   168   
-11 Multiple myeloma   77   
-12 Multiple myeloma   151   
-13 Multiple myeloma   669   
-14 Multiple myeloma   313   
-15 Multiple myeloma   88   
-16 Multiple myeloma   274   
-17 Multiple myeloma   168   
-18 Multiple myeloma   119   
-19 Multiple myeloma   61   
-20 Multiple myeloma   173   
-21 Multiple myeloma   95   
-22 Multiple myeloma   242   
-X Multiple myeloma   352   
-Y Multiple myeloma   281