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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p11 t(11;12)(p11;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p11 t(1;11)(p34;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p13 t(11;14)(p13;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma   102  LMO2/TRA,LMO2/TRAC,LMO2+,TRA/LMO2,TRA+,TRD/LMO2,TRD+
11p13 t(11;14)(p13;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   10   
11p13 t(7;11)(q34;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   TRB/LMO2,TRB+
11p13 t(7;11)(q35;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p14 t(11;14)(p14;q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p15 inv(11)(p15q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p15 t(11;14)(p15;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma   LMO1/TRA,LMO1/TRAC,TRA+,TRD/LMO1
11p15 t(2;11)(q11;p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma   DA926692+,HPS5+
11p15 t(3;11)(q12;p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma   NUP98/LNP1
11p15 t(4;11)(q21;p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma   13   
11p15 t(7;11)(q34;p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma   RIC3/TRB,RIC3/TRBC2,TRB/LMO1
11p15 t(9;11)(p13;p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma   DBX1/PAX5
11p15 t(X;10;11)(p11;p11;p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q11 ins(4;11)(q21;q11q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+
11q13 ins(10;11)(p12;q23q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/MLLT10
11q13 ins(4;11)(q21;q13q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   ATG16L2/KMT2A,KMT2A/AFF1
11q13 t(10;11)(p13;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 t(11;14)(q13;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 t(11;14)(q13;q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 t(11;19)(q13;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 t(1;11)(p32;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 t(9;22;11)(q34;q11;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   BCR/ABL1
11q14 t(10;11)(p12;q14) Acute lymphoblastic leukemia/lymphoblastic lymphoma   MLLT10/EED,MLLT10/PICALM,PICALM/MLLT10,PICALM+
11q14 t(10;11)(p13;q14) Acute lymphoblastic leukemia/lymphoblastic lymphoma   16   
11q14 t(10;11)(p14;q14) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q21 inv(11)(q21q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/MAML2
11q21 t(10;11)(p12;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q21 t(10;11)(p13;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma   20   
11q21 t(10;11)(p14;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q22 t(4;11)(q13;q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 ins(10;11)(p12;q23q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/MLLT10
11q23 ins(10;11)(p12;q23q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+,KMT2A/MLLT10
11q23 ins(10;11)(p12;q23q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+,KMT2A/MLLT10
11q23 ins(4;11)(q21;q11q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+
11q23 ins(4;11)(q21;q13q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   ATG16L2/KMT2A,KMT2A/AFF1
11q23 ins(4;11)(q21;q23q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   AFF1/DSCAML1,AFF1/FXYD6,DSCAML1/KMT2A,FXYD6/KMT2A,KMT2A/AFF1,KMT2A+,ATG16L2/KMT2A
11q23 ins(4;11)(q21;q23q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   AFF1/DSCAML1,AFF1/FXYD6,DSCAML1/KMT2A,FXYD6/KMT2A,KMT2A/AFF1,KMT2A+,ATG16L2/KMT2A
11q23 inv(11)(p15q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 inv(11)(q21q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/MAML2
11q23 t(10;11)(p12;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/MLLT10
11q23 t(11;14)(q23;q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma   IGH/DDX6
11q23 t(11;16)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/CREBBP,KMT2A+
11q23 t(11;17)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/GAS7,KMT2A+
11q23 t(11;17)(q23;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 t(11;17)(q23;q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 t(11;19)(q23;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+
11q23 t(11;19)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   159  KMT2A/ELL,KMT2A/MLLT1,KMT2A+
11q23 t(11;20)(q23;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 t(1;11)(p32;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   19  KMT2A/EPS15,KMT2A+
11q23 t(2;11)(p21;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+
11q23 t(2;4;11)(p21;q21;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 t(4;11)(q21;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   586  AFF1/CCDC84,AFF1/KMT2A,KMT2A/AFF1,KMT2A/SEPT11,KMT2A+
11q23 t(4;11;13)(q21;q23;q14) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 t(5;11)(q31;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/AFF4,KMT2A/MATR3,KMT2A+
11q23 t(6;11)(q27;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   16  KMT2A/MLLT4,KMT2A+
11q23 t(9;11)(p21;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/MLLT3
11q23 t(9;11)(p22;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   24   
11q24 t(11;14)(q24;q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma   IGH/MIR125B1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p11 add(11)(p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma   14   
11p11 del(11)(p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p11 del(11)(p11p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p12 del(11)(p12) Acute lymphoblastic leukemia/lymphoblastic lymphoma   LMO2+
11p13 add(11)(p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   10   
11p13 del(11)(p11p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p13 del(11)(p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   11  LMO2+
11p14 add(11)(p14) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p14 del(11)(p14) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p14 der(2)t(2;11)(p23;p14) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11p15 add(11)(p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma   15   
11p15 del(11)(p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q10 del(11)(q10) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q10 i(11)(q10) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q12 del(11)(q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q12 der(5)t(5;11)(q35;q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 add(11)(q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 del(11)(q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   22   
11q13 del(11)(q13q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   17   
11q13 del(11)(q13q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 der(11)t(7;11)(q11;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 der(19)t(11;19)(q13;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q13 dup(11)(q13q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q14 del(11)(q14) Acute lymphoblastic leukemia/lymphoblastic lymphoma   14  KMT2A+
11q14 del(11)(q14q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   16  KMT2A+
11q14 del(11)(q14q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q14 del(11)(q14q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q14 der(11)t(1;11)(q21;q14) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q21 add(11)(q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q21 del(11)(q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma   26   
11q21 del(11)(q21q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   15   
11q21 der(9)t(9;11)(p13;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q22 add(11)(q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q22 del(11)(q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma   17   
11q22 del(11)(q22q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q22 del(11)(q22q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q22 del(11)(q22q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 add(11)(q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   47  KMT2A+
11q23 del(11)(q13q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   17   
11q23 del(11)(q14q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   16  KMT2A+
11q23 del(11)(q21q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   15   
11q23 del(11)(q22q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 del(11)(q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   118  KMT2A+,KMT2A/BCL9L
11q23 del(11)(q23q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/BCL9L,KMT2A+
11q23 del(11)(q23q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A/BCL9L,KMT2A+
11q23 del(11)(q23q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+
11q23 del(11)(q23q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+
11q23 der(11)(q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+
11q23 der(11)t(1;11)(q21;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 der(11)t(4;11)(q21;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 der(19)t(11;19)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 der(21)t(9;11;21)(q33;q23;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 der(4)t(4;11)(q21;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 dup(11)(q13q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q23 hsr(11)(q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q24 add(11)(q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q24 del(11)(q14q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q24 del(11)(q22q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q24 del(11)(q23q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+
11q24 der(14)t(11;14)(q24;q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q25 add(11)(q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q25 del(11)(q13q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q25 del(11)(q14q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q25 del(11)(q22q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
11q25 del(11)(q23q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma   KMT2A+

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Acute lymphoblastic leukemia/lymphoblastic lymphoma   150   
+2 Acute lymphoblastic leukemia/lymphoblastic lymphoma   141   
+3 Acute lymphoblastic leukemia/lymphoblastic lymphoma   78   
+4 Acute lymphoblastic leukemia/lymphoblastic lymphoma   964   
+5 Acute lymphoblastic leukemia/lymphoblastic lymphoma   409   
+6 Acute lymphoblastic leukemia/lymphoblastic lymphoma   1101   
+7 Acute lymphoblastic leukemia/lymphoblastic lymphoma   171   
+8 Acute lymphoblastic leukemia/lymphoblastic lymphoma   944   
+9 Acute lymphoblastic leukemia/lymphoblastic lymphoma   288   
+10 Acute lymphoblastic leukemia/lymphoblastic lymphoma   1020   
+11 Acute lymphoblastic leukemia/lymphoblastic lymphoma   247   
+12 Acute lymphoblastic leukemia/lymphoblastic lymphoma   199   
+13 Acute lymphoblastic leukemia/lymphoblastic lymphoma   207   
+14 Acute lymphoblastic leukemia/lymphoblastic lymphoma   1113   
+15 Acute lymphoblastic leukemia/lymphoblastic lymphoma   184   
+16 Acute lymphoblastic leukemia/lymphoblastic lymphoma   166   
+17 Acute lymphoblastic leukemia/lymphoblastic lymphoma   790   
+18 Acute lymphoblastic leukemia/lymphoblastic lymphoma   1009   
+19 Acute lymphoblastic leukemia/lymphoblastic lymphoma   286   
+20 Acute lymphoblastic leukemia/lymphoblastic lymphoma   217   
+21 Acute lymphoblastic leukemia/lymphoblastic lymphoma   2211   
+22 Acute lymphoblastic leukemia/lymphoblastic lymphoma   411   
+X Acute lymphoblastic leukemia/lymphoblastic lymphoma   1553   
+Y Acute lymphoblastic leukemia/lymphoblastic lymphoma   253   

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Acute lymphoblastic leukemia/lymphoblastic lymphoma   275   
-2 Acute lymphoblastic leukemia/lymphoblastic lymphoma   332   
-3 Acute lymphoblastic leukemia/lymphoblastic lymphoma   423   
-4 Acute lymphoblastic leukemia/lymphoblastic lymphoma   240   
-5 Acute lymphoblastic leukemia/lymphoblastic lymphoma   231   
-6 Acute lymphoblastic leukemia/lymphoblastic lymphoma   128   
-7 Acute lymphoblastic leukemia/lymphoblastic lymphoma   674   
-8 Acute lymphoblastic leukemia/lymphoblastic lymphoma   256   
-9 Acute lymphoblastic leukemia/lymphoblastic lymphoma   505   
-10 Acute lymphoblastic leukemia/lymphoblastic lymphoma   187   
-11 Acute lymphoblastic leukemia/lymphoblastic lymphoma   253   
-12 Acute lymphoblastic leukemia/lymphoblastic lymphoma   338   
-13 Acute lymphoblastic leukemia/lymphoblastic lymphoma   503   
-14 Acute lymphoblastic leukemia/lymphoblastic lymphoma   225   
-15 Acute lymphoblastic leukemia/lymphoblastic lymphoma   453   
-16 Acute lymphoblastic leukemia/lymphoblastic lymphoma   410   
-17 Acute lymphoblastic leukemia/lymphoblastic lymphoma   354   
-18 Acute lymphoblastic leukemia/lymphoblastic lymphoma   187   
-19 Acute lymphoblastic leukemia/lymphoblastic lymphoma   318   
-20 Acute lymphoblastic leukemia/lymphoblastic lymphoma   475   
-21 Acute lymphoblastic leukemia/lymphoblastic lymphoma   258   
-22 Acute lymphoblastic leukemia/lymphoblastic lymphoma   263   
-X Acute lymphoblastic leukemia/lymphoblastic lymphoma   294   
-Y Acute lymphoblastic leukemia/lymphoblastic lymphoma   223