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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q23 t(2;11)(p21;q23) Refractory anemia    
11q23 t(9;11)(p22;q23) Refractory anemia    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q13 del(11)(q13q23) Refractory anemia    
11q14 del(11)(q14) Refractory anemia    
11q14 del(11)(q14q23) Refractory anemia    
11q21 del(11)(q21q23) Refractory anemia    
11q23 del(11)(q13q23) Refractory anemia    
11q23 del(11)(q14q23) Refractory anemia    
11q23 del(11)(q21q23) Refractory anemia    
11q23 del(11)(q23) Refractory anemia    
11q24 der(11)t(11;21)(q24;q11) Refractory anemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Refractory anemia   97   
+2 Refractory anemia    
+3 Refractory anemia    
+6 Refractory anemia    
+8 Refractory anemia   170   
+9 Refractory anemia    
+10 Refractory anemia    
+11 Refractory anemia    
+13 Refractory anemia    
+14 Refractory anemia    
+15 Refractory anemia   10   
+16 Refractory anemia    
+18 Refractory anemia    
+19 Refractory anemia   12   
+20 Refractory anemia    
+21 Refractory anemia   39   
+22 Refractory anemia    
+X Refractory anemia    
+Y Refractory anemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Refractory anemia    
-2 Refractory anemia    
-3 Refractory anemia    
-4 Refractory anemia    
-5 Refractory anemia   37   
-6 Refractory anemia    
-7 Refractory anemia   118   
-8 Refractory anemia    
-9 Refractory anemia    
-10 Refractory anemia    
-11 Refractory anemia    
-12 Refractory anemia   16   
-13 Refractory anemia   12   
-14 Refractory anemia   11   
-15 Refractory anemia    
-16 Refractory anemia    
-17 Refractory anemia   20   
-18 Refractory anemia   27   
-19 Refractory anemia    
-20 Refractory anemia   25   
-21 Refractory anemia   16   
-22 Refractory anemia   12   
-X Refractory anemia   11   
-Y Refractory anemia   46