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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p15 t(7;11)(p15;p15) Chronic myelomonocytic leukemia   NUP98/HOXA9
11q23 t(11;16)(q23;p13) Chronic myelomonocytic leukemia   KMT2A/CREBBP
11q23 t(11;19)(q23;p13) Chronic myelomonocytic leukemia   KMT2A/ELL,KMT2A+
11q23 t(9;11)(p22;q23) Chronic myelomonocytic leukemia   KMT2A+

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q23 del(11)(q23) Chronic myelomonocytic leukemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Chronic myelomonocytic leukemia   11   
+2 Chronic myelomonocytic leukemia    
+4 Chronic myelomonocytic leukemia    
+5 Chronic myelomonocytic leukemia    
+6 Chronic myelomonocytic leukemia    
+7 Chronic myelomonocytic leukemia    
+8 Chronic myelomonocytic leukemia   92   
+9 Chronic myelomonocytic leukemia    
+10 Chronic myelomonocytic leukemia    
+11 Chronic myelomonocytic leukemia    
+12 Chronic myelomonocytic leukemia    
+13 Chronic myelomonocytic leukemia    
+14 Chronic myelomonocytic leukemia    
+19 Chronic myelomonocytic leukemia   11   
+20 Chronic myelomonocytic leukemia    
+21 Chronic myelomonocytic leukemia   24   
+22 Chronic myelomonocytic leukemia    
+Y Chronic myelomonocytic leukemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Chronic myelomonocytic leukemia    
-3 Chronic myelomonocytic leukemia    
-4 Chronic myelomonocytic leukemia    
-5 Chronic myelomonocytic leukemia    
-6 Chronic myelomonocytic leukemia    
-7 Chronic myelomonocytic leukemia   52   
-8 Chronic myelomonocytic leukemia    
-10 Chronic myelomonocytic leukemia    
-12 Chronic myelomonocytic leukemia    
-13 Chronic myelomonocytic leukemia    
-15 Chronic myelomonocytic leukemia    
-16 Chronic myelomonocytic leukemia    
-17 Chronic myelomonocytic leukemia   11   
-18 Chronic myelomonocytic leukemia    
-19 Chronic myelomonocytic leukemia    
-20 Chronic myelomonocytic leukemia    
-21 Chronic myelomonocytic leukemia    
-22 Chronic myelomonocytic leukemia    
-X Chronic myelomonocytic leukemia    
-Y Chronic myelomonocytic leukemia   32