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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p15 t(11;22)(p15;q11) Chronic myeloid leukemia, aberrant translocation   BCR+
11p15 t(9;11;22)(q34;p15;q11) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1
11p15 t(9;22;11)(q34;q11;p15) Chronic myeloid leukemia, aberrant translocation    
11q11 t(9;11)(q34;q11) Chronic myeloid leukemia, aberrant translocation    
11q12 t(9;22;11)(q34;q11;q12) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1
11q13 t(11;22)(q13;q11) Chronic myeloid leukemia, aberrant translocation    
11q13 t(9;11;22)(q34;q13;q11) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1,BCR+
11q13 t(9;22;11)(q34;q11;q13) Chronic myeloid leukemia, aberrant translocation   18  BCR/ABL1,BCR+,GSTP1+
11q23 t(11;19)(q23;p13) Chronic myeloid leukemia, aberrant translocation    
11q23 t(9;22;11)(q34;q11;q23) Chronic myeloid leukemia, aberrant translocation    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q13 del(11)(q13) Chronic myeloid leukemia, aberrant translocation    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+2 Chronic myeloid leukemia, aberrant translocation    
+3 Chronic myeloid leukemia, aberrant translocation    
+4 Chronic myeloid leukemia, aberrant translocation    
+5 Chronic myeloid leukemia, aberrant translocation    
+6 Chronic myeloid leukemia, aberrant translocation    
+8 Chronic myeloid leukemia, aberrant translocation   83   
+9 Chronic myeloid leukemia, aberrant translocation    
+10 Chronic myeloid leukemia, aberrant translocation   10   
+11 Chronic myeloid leukemia, aberrant translocation    
+12 Chronic myeloid leukemia, aberrant translocation    
+13 Chronic myeloid leukemia, aberrant translocation    
+14 Chronic myeloid leukemia, aberrant translocation    
+15 Chronic myeloid leukemia, aberrant translocation    
+17 Chronic myeloid leukemia, aberrant translocation    
+18 Chronic myeloid leukemia, aberrant translocation    
+19 Chronic myeloid leukemia, aberrant translocation   19   
+20 Chronic myeloid leukemia, aberrant translocation    
+21 Chronic myeloid leukemia, aberrant translocation   17   
+22 Chronic myeloid leukemia, aberrant translocation    
+X Chronic myeloid leukemia, aberrant translocation    
+Y Chronic myeloid leukemia, aberrant translocation    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Chronic myeloid leukemia, aberrant translocation    
-3 Chronic myeloid leukemia, aberrant translocation    
-4 Chronic myeloid leukemia, aberrant translocation    
-5 Chronic myeloid leukemia, aberrant translocation    
-7 Chronic myeloid leukemia, aberrant translocation    
-9 Chronic myeloid leukemia, aberrant translocation    
-10 Chronic myeloid leukemia, aberrant translocation    
-12 Chronic myeloid leukemia, aberrant translocation    
-14 Chronic myeloid leukemia, aberrant translocation    
-15 Chronic myeloid leukemia, aberrant translocation    
-16 Chronic myeloid leukemia, aberrant translocation    
-17 Chronic myeloid leukemia, aberrant translocation    
-18 Chronic myeloid leukemia, aberrant translocation   11   
-19 Chronic myeloid leukemia, aberrant translocation    
-20 Chronic myeloid leukemia, aberrant translocation    
-21 Chronic myeloid leukemia, aberrant translocation    
-22 Chronic myeloid leukemia, aberrant translocation    
-X Chronic myeloid leukemia, aberrant translocation    
-Y Chronic myeloid leukemia, aberrant translocation   22