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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p15 t(11;20)(p15;q11) Acute monoblastic leukemia (FAB type M5)    
11p15 t(5;11)(q35;p15) Acute monoblastic leukemia (FAB type M5)   10  NUP98/NSD1
11q13 ins(10;11)(p11;q23q13) Acute monoblastic leukemia (FAB type M5)   KMT2A+
11q13 ins(10;11)(p12;q23q13) Acute monoblastic leukemia (FAB type M5)   KMT2A/MLLT10,KMT2A+
11q13 t(9;11)(p22;q13) Acute monoblastic leukemia (FAB type M5)    
11q21 ins(10;11)(p13;q23q21) Acute monoblastic leukemia (FAB type M5)    
11q21 t(10;11)(p12;q21) Acute monoblastic leukemia (FAB type M5)    
11q21 t(10;11)(p13;q21) Acute monoblastic leukemia (FAB type M5)    
11q21 t(10;11)(p14;q21) Acute monoblastic leukemia (FAB type M5)    
11q23 ins(10;11)(p11;q23q13) Acute monoblastic leukemia (FAB type M5)   KMT2A+
11q23 ins(10;11)(p12;q23q13) Acute monoblastic leukemia (FAB type M5)   KMT2A/MLLT10,KMT2A+
11q23 ins(10;11)(p12;q23q23) Acute monoblastic leukemia (FAB type M5)   KMT2A/MLLT10,MLLT10/CLP1,KMT2A+
11q23 ins(10;11)(p12;q23q23) Acute monoblastic leukemia (FAB type M5)   KMT2A/MLLT10,MLLT10/CLP1,KMT2A+
11q23 ins(10;11)(p13;q23q21) Acute monoblastic leukemia (FAB type M5)    
11q23 t(10;11)(p11;q23) Acute monoblastic leukemia (FAB type M5)    
11q23 t(10;11)(p12;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A/MLLT10,KMT2A+,MLLT10/CEP164,MLLT10/KMT2A,MLLT10/PPP2R1B
11q23 t(10;11)(p13;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A+
11q23 t(10;11)(p15;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A+
11q23 t(11;16)(q23;p13) Acute monoblastic leukemia (FAB type M5)    
11q23 t(11;17)(q23;q21) Acute monoblastic leukemia (FAB type M5)   KMT2A+,RARA+
11q23 t(11;17)(q23;q25) Acute monoblastic leukemia (FAB type M5)   KMT2A/SEPT9
11q23 t(11;19)(q23;p13) Acute monoblastic leukemia (FAB type M5)   28  KMT2A/ELL,KMT2A/MLLT1,KMT2A/MYO1F
11q23 t(1;11)(q21;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A/MLLT11
11q23 t(1;11;10)(p32;q23;q24) Acute monoblastic leukemia (FAB type M5)   KMT2A/EPS15,NT5C2/KMT2A
11q23 t(1;19;11)(p36;p13;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A/ELL
11q23 t(4;11)(q21;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A/AFF1
11q23 t(5;11)(q31;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A/ARHGAP26
11q23 t(6;11)(q27;q23) Acute monoblastic leukemia (FAB type M5)   15  KMT2A/MLLT4,KMT2A+
11q23 t(9;11)(p21;q23) Acute monoblastic leukemia (FAB type M5)   56  KMT2A/MLLT3,KMT2A+
11q23 t(9;11)(p22;q23) Acute monoblastic leukemia (FAB type M5)   102   
11q23 t(9;11)(q21;q23) Acute monoblastic leukemia (FAB type M5)    
11q23 t(9;11)(q22;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A+
11q24 t(9;11)(p22;q24) Acute monoblastic leukemia (FAB type M5)    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p11 add(11)(p11) Acute monoblastic leukemia (FAB type M5)    
11p13 add(11)(p13) Acute monoblastic leukemia (FAB type M5)    
11p13 del(11)(p13) Acute monoblastic leukemia (FAB type M5)    
11q10 i(11)(q10) Acute monoblastic leukemia (FAB type M5)    
11q13 del(11)(q13) Acute monoblastic leukemia (FAB type M5)    
11q13 del(11)(q13q23) Acute monoblastic leukemia (FAB type M5)    
11q13 der(10)t(10;11)(p12;q23)inv(11)(q13q23) Acute monoblastic leukemia (FAB type M5)    
11q13 der(11)t(10;11)(p12;q13) Acute monoblastic leukemia (FAB type M5)    
11q14 del(11)(q14) Acute monoblastic leukemia (FAB type M5)    
11q21 del(11)(q21) Acute monoblastic leukemia (FAB type M5)    
11q21 del(11)(q21q23) Acute monoblastic leukemia (FAB type M5)    
11q22 del(11)(q22) Acute monoblastic leukemia (FAB type M5)    
11q22 del(11)(q22q24) Acute monoblastic leukemia (FAB type M5)    
11q23 add(11)(q23) Acute monoblastic leukemia (FAB type M5)   KMT2A+
11q23 del(11)(q13q23) Acute monoblastic leukemia (FAB type M5)    
11q23 del(11)(q21q23) Acute monoblastic leukemia (FAB type M5)    
11q23 del(11)(q23) Acute monoblastic leukemia (FAB type M5)   27  KMT2A+
11q23 der(10)ins(10;11)(p12;q23q23) Acute monoblastic leukemia (FAB type M5)    
11q23 der(10)ins(10;11)(p12;q23q23) Acute monoblastic leukemia (FAB type M5)    
11q23 der(10)t(10;11)(p12;q23) Acute monoblastic leukemia (FAB type M5)    
11q23 der(10)t(10;11)(p12;q23)inv(11)(q13q23) Acute monoblastic leukemia (FAB type M5)    
11q23 der(10)t(10;11)(p12;q23)inv(11)(q13q23) Acute monoblastic leukemia (FAB type M5)    
11q23 der(11)t(9;11)(p22;q23) Acute monoblastic leukemia (FAB type M5)    
11q23 der(9)t(9;11)(p21;q23) Acute monoblastic leukemia (FAB type M5)    
11q23 der(9)t(9;11)(p22;q23) Acute monoblastic leukemia (FAB type M5)    
11q24 del(11)(q22q24) Acute monoblastic leukemia (FAB type M5)    
11q25 add(11)(q25) Acute monoblastic leukemia (FAB type M5)    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Acute monoblastic leukemia (FAB type M5)   15   
+2 Acute monoblastic leukemia (FAB type M5)    
+3 Acute monoblastic leukemia (FAB type M5)   10   
+4 Acute monoblastic leukemia (FAB type M5)   20   
+5 Acute monoblastic leukemia (FAB type M5)   12   
+6 Acute monoblastic leukemia (FAB type M5)   27   
+7 Acute monoblastic leukemia (FAB type M5)    
+8 Acute monoblastic leukemia (FAB type M5)   217   
+9 Acute monoblastic leukemia (FAB type M5)   14   
+10 Acute monoblastic leukemia (FAB type M5)   18   
+11 Acute monoblastic leukemia (FAB type M5)   25   
+12 Acute monoblastic leukemia (FAB type M5)   11   
+13 Acute monoblastic leukemia (FAB type M5)   32   
+14 Acute monoblastic leukemia (FAB type M5)   14   
+15 Acute monoblastic leukemia (FAB type M5)    
+16 Acute monoblastic leukemia (FAB type M5)    
+17 Acute monoblastic leukemia (FAB type M5)    
+18 Acute monoblastic leukemia (FAB type M5)    
+19 Acute monoblastic leukemia (FAB type M5)   43   
+20 Acute monoblastic leukemia (FAB type M5)   10   
+21 Acute monoblastic leukemia (FAB type M5)   57   
+22 Acute monoblastic leukemia (FAB type M5)   13   
+X Acute monoblastic leukemia (FAB type M5)   10   
+Y Acute monoblastic leukemia (FAB type M5)    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-2 Acute monoblastic leukemia (FAB type M5)    
-3 Acute monoblastic leukemia (FAB type M5)    
-4 Acute monoblastic leukemia (FAB type M5)    
-5 Acute monoblastic leukemia (FAB type M5)   16   
-6 Acute monoblastic leukemia (FAB type M5)    
-7 Acute monoblastic leukemia (FAB type M5)   57   
-8 Acute monoblastic leukemia (FAB type M5)   10   
-9 Acute monoblastic leukemia (FAB type M5)    
-10 Acute monoblastic leukemia (FAB type M5)   17   
-11 Acute monoblastic leukemia (FAB type M5)   10   
-12 Acute monoblastic leukemia (FAB type M5)   14   
-13 Acute monoblastic leukemia (FAB type M5)   10   
-14 Acute monoblastic leukemia (FAB type M5)   12   
-15 Acute monoblastic leukemia (FAB type M5)   12   
-16 Acute monoblastic leukemia (FAB type M5)    
-17 Acute monoblastic leukemia (FAB type M5)   30   
-18 Acute monoblastic leukemia (FAB type M5)   18   
-19 Acute monoblastic leukemia (FAB type M5)    
-20 Acute monoblastic leukemia (FAB type M5)   10   
-21 Acute monoblastic leukemia (FAB type M5)   15   
-22 Acute monoblastic leukemia (FAB type M5)    
-X Acute monoblastic leukemia (FAB type M5)   17   
-Y Acute monoblastic leukemia (FAB type M5)   18