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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q13 ins(10;11)(p12;q23q13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT10
11q21 t(10;11)(p13;q21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 ins(10;11)(p12;q23q13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT10
11q23 t(10;11)(p12;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT10
11q23 t(11;17)(q23;q25) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/SEPT9
11q23 t(11;19)(q23;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT1,KMT2A+
11q23 t(2;11)(p21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A+
11q23 t(4;11)(q21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/AFF1
11q23 t(9;11)(p21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT3,KMT2A+
11q23 t(9;11)(p22;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p11 del(11)(p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11p11 dic(7;11)(q11;p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11p15 add(11)(p15) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q10 der(11;15)(q10;q10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q10 i(11)(q10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q13 del(11)(q13q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q13 der(17)t(11;17)(q13;p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q21 del(11)(q21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q21 del(11)(q21q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 add(11)(q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 del(11)(q13q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 del(11)(q21q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 del(11)(q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A+
11q25 add(11)(q25) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   13   
+2 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+3 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+4 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   26   
+5 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+6 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   11   
+7 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+8 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   72   
+9 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   10   
+10 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   12   
+11 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
+12 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+13 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   85   
+14 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   13   
+15 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+16 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+17 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+18 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+19 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   37   
+20 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   10   
+21 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   30   
+22 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
+X Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   11   
+Y Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-2 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-3 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   21   
-4 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-5 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   30   
-6 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-7 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   85   
-8 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-9 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-10 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-11 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-12 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   17   
-13 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   13   
-14 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   14   
-15 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   19   
-16 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
-17 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   41   
-18 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   19   
-19 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-20 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
-21 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
-22 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-X Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   15   
-Y Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   17