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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p15 inv(11)(p15q22) Acute myeloid leukemia, NOS   NUP98/DDX10,NUP98+
11p15 inv(11)(p15q23) Acute myeloid leukemia, NOS    
11p15 t(11;11)(p15;q22) Acute myeloid leukemia, NOS    
11p15 t(11;12)(p15;q13) Acute myeloid leukemia, NOS    
11p15 t(11;17)(p15;q21) Acute myeloid leukemia, NOS   NUP98+
11p15 t(11;20)(p15;q11) Acute myeloid leukemia, NOS    
11p15 t(11;20)(p15;q12) Acute myeloid leukemia, NOS   NUP98/TOP1
11p15 t(2;11)(q31;p15) Acute myeloid leukemia, NOS    
11p15 t(3;11)(q12;p15) Acute myeloid leukemia, NOS    
11p15 t(5;11)(q35;p15) Acute myeloid leukemia, NOS   NUP98/NSD1
11p15 t(7;11)(p15;p15) Acute myeloid leukemia, NOS   NUP98/HOXA9
11p15 t(8;11)(p11;p15) Acute myeloid leukemia, NOS   FGFR1+
11q13 ins(10;11)(p13;q23q13) Acute myeloid leukemia, NOS   KMT2A+
11q13 t(10;11)(p13;q13) Acute myeloid leukemia, NOS    
11q13 t(7;11)(q22;q13) Acute myeloid leukemia, NOS    
11q13 t(9;11)(p22;q13) Acute myeloid leukemia, NOS    
11q14 t(10;11)(p13;q14) Acute myeloid leukemia, NOS    
11q21 t(10;11)(p13;q21) Acute myeloid leukemia, NOS    
11q22 inv(11)(p15q22) Acute myeloid leukemia, NOS   NUP98/DDX10,NUP98+
11q22 t(11;11)(p15;q22) Acute myeloid leukemia, NOS    
11q23 ins(10;11)(p13;q23q13) Acute myeloid leukemia, NOS   KMT2A+
11q23 inv(11)(p15q23) Acute myeloid leukemia, NOS    
11q23 t(10;11)(p11;q23) Acute myeloid leukemia, NOS   KMT2A+
11q23 t(11;15)(q23;q14) Acute myeloid leukemia, NOS   KMT2A+
11q23 t(11;16)(q23;p13) Acute myeloid leukemia, NOS   KMT2A/CREBBP,KMT2A/MYH11,KMT2A+
11q23 t(11;17)(q23;q21) Acute myeloid leukemia, NOS   KMT2A+,ZBTB16/RARA
11q23 t(11;17)(q23;q25) Acute myeloid leukemia, NOS   KMT2A/SEPT9,KMT2A+
11q23 t(11;19)(q23;p13) Acute myeloid leukemia, NOS   48  KMT2A/ELL,KMT2A/MLLT1,KMT2A/MYO1F,KMT2A/SH3GL1,KMT2A/VAV1,KMT2A+
11q23 t(11;22)(q23;q11) Acute myeloid leukemia, NOS   KMT2A/SEPT5,KMT2A+
11q23 t(11;22)(q23;q13) Acute myeloid leukemia, NOS   KMT2A/EP300
11q23 t(1;11)(q21;q23) Acute myeloid leukemia, NOS   KMT2A/MLLT11,KMT2A+
11q23 t(2;11)(p21;q23) Acute myeloid leukemia, NOS   KMT2A+
11q23 t(4;11)(q21;q23) Acute myeloid leukemia, NOS   KMT2A/AFF1,KMT2A/SEPT11
11q23 t(6;11)(q21;q23) Acute myeloid leukemia, NOS    
11q23 t(6;11)(q27;q23) Acute myeloid leukemia, NOS   15  KMT2A/MLLT4,KMT2A+
11q23 t(9;11)(p21;q23) Acute myeloid leukemia, NOS   KMT2A/MLLT3,KMT2A+
11q23 t(9;11)(p22;q23) Acute myeloid leukemia, NOS   51   

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11p11 add(11)(p11) Acute myeloid leukemia, NOS   10   
11p11 del(11)(p11) Acute myeloid leukemia, NOS    
11p11 del(11)(p11p13) Acute myeloid leukemia, NOS    
11p11 del(11)(p11p14) Acute myeloid leukemia, NOS    
11p11 del(11)(p11p15) Acute myeloid leukemia, NOS    
11p11 idic(11)(p11) Acute myeloid leukemia, NOS    
11p12 add(11)(p12) Acute myeloid leukemia, NOS    
11p12 del(11)(p12) Acute myeloid leukemia, NOS    
11p13 del(11)(p11p13) Acute myeloid leukemia, NOS    
11p13 del(11)(p13) Acute myeloid leukemia, NOS    
11p14 add(11)(p14) Acute myeloid leukemia, NOS    
11p14 del(11)(p11p14) Acute myeloid leukemia, NOS    
11p14 del(11)(p14) Acute myeloid leukemia, NOS    
11p15 add(11)(p15) Acute myeloid leukemia, NOS   23  NUP98+
11p15 del(11)(p11p15) Acute myeloid leukemia, NOS    
11p15 der(11)t(11;11)(p15;q13) Acute myeloid leukemia, NOS    
11q10 i(11)(q10) Acute myeloid leukemia, NOS   15   
11q11 del(11)(q11) Acute myeloid leukemia, NOS    
11q12 dup(11)(q12q13) Acute myeloid leukemia, NOS    
11q13 add(11)(q13) Acute myeloid leukemia, NOS    
11q13 del(11)(q13) Acute myeloid leukemia, NOS    
11q13 del(11)(q13q23) Acute myeloid leukemia, NOS    
11q13 der(11)t(11;11)(p15;q13) Acute myeloid leukemia, NOS    
11q13 der(17)t(11;17)(q13;p13) Acute myeloid leukemia, NOS    
11q13 der(20)t(11;20)(q13;p13) Acute myeloid leukemia, NOS    
11q13 der(5)t(5;11)(q15;q13) Acute myeloid leukemia, NOS    
11q13 der(7)t(7;11)(q11;q13) Acute myeloid leukemia, NOS    
11q13 dup(11)(q12q13) Acute myeloid leukemia, NOS    
11q14 del(11)(q14) Acute myeloid leukemia, NOS   KMT2A+
11q14 del(11)(q14q23) Acute myeloid leukemia, NOS   KMT2A+
11q21 del(11)(q21) Acute myeloid leukemia, NOS    
11q21 del(11)(q21q23) Acute myeloid leukemia, NOS    
11q21 del(11)(q21q25) Acute myeloid leukemia, NOS    
11q22 add(11)(q22) Acute myeloid leukemia, NOS    
11q22 del(11)(q22) Acute myeloid leukemia, NOS    
11q23 add(11)(q23) Acute myeloid leukemia, NOS   30  +KMT2A,KMT2A+
11q23 del(11)(q13q23) Acute myeloid leukemia, NOS    
11q23 del(11)(q14q23) Acute myeloid leukemia, NOS   KMT2A+
11q23 del(11)(q21q23) Acute myeloid leukemia, NOS    
11q23 del(11)(q23) Acute myeloid leukemia, NOS   32  KMT2A+,KMT2A/DCPS,KMT2A/TIRAP
11q23 del(11)(q23q25) Acute myeloid leukemia, NOS    
11q23 der(11)t(1;11)(q21;q23) Acute myeloid leukemia, NOS    
11q23 der(6)t(6;11)(q27;q23) Acute myeloid leukemia, NOS    
11q23 der(9)t(9;11)(p22;q23) Acute myeloid leukemia, NOS    
11q23 dup(11)(q23q23) Acute myeloid leukemia, NOS    
11q23 dup(11)(q23q23) Acute myeloid leukemia, NOS    
11q23 hsr(11)(q23) Acute myeloid leukemia, NOS   +KMT2A
11q24 add(11)(q24) Acute myeloid leukemia, NOS    
11q24 del(11)(q24) Acute myeloid leukemia, NOS   KMT2A/DCPS,KMT2A/TIRAP
11q25 add(11)(q25) Acute myeloid leukemia, NOS    
11q25 del(11)(q21q25) Acute myeloid leukemia, NOS    
11q25 del(11)(q23q25) Acute myeloid leukemia, NOS    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Acute myeloid leukemia, NOS   106   
+2 Acute myeloid leukemia, NOS   56   
+3 Acute myeloid leukemia, NOS   39   
+4 Acute myeloid leukemia, NOS   77   
+5 Acute myeloid leukemia, NOS   24   
+6 Acute myeloid leukemia, NOS   101   
+7 Acute myeloid leukemia, NOS   24   
+8 Acute myeloid leukemia, NOS   829   
+9 Acute myeloid leukemia, NOS   116   
+10 Acute myeloid leukemia, NOS   79   
+11 Acute myeloid leukemia, NOS   173   
+12 Acute myeloid leukemia, NOS   30   
+13 Acute myeloid leukemia, NOS   182   
+14 Acute myeloid leukemia, NOS   105   
+15 Acute myeloid leukemia, NOS   76   
+16 Acute myeloid leukemia, NOS   28   
+17 Acute myeloid leukemia, NOS   16   
+18 Acute myeloid leukemia, NOS   51   
+19 Acute myeloid leukemia, NOS   154   
+20 Acute myeloid leukemia, NOS   79   
+21 Acute myeloid leukemia, NOS   302   
+22 Acute myeloid leukemia, NOS   157   
+X Acute myeloid leukemia, NOS   34   
+Y Acute myeloid leukemia, NOS   35   

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Acute myeloid leukemia, NOS   38   
-2 Acute myeloid leukemia, NOS   55   
-3 Acute myeloid leukemia, NOS   185   
-4 Acute myeloid leukemia, NOS   118   
-5 Acute myeloid leukemia, NOS   367   
-6 Acute myeloid leukemia, NOS   90   
-7 Acute myeloid leukemia, NOS   1011   
-8 Acute myeloid leukemia, NOS   84   
-9 Acute myeloid leukemia, NOS   112   
-10 Acute myeloid leukemia, NOS   71   
-11 Acute myeloid leukemia, NOS   116   
-12 Acute myeloid leukemia, NOS   204   
-13 Acute myeloid leukemia, NOS   160   
-14 Acute myeloid leukemia, NOS   102   
-15 Acute myeloid leukemia, NOS   152   
-16 Acute myeloid leukemia, NOS   232   
-17 Acute myeloid leukemia, NOS   410   
-18 Acute myeloid leukemia, NOS   301   
-19 Acute myeloid leukemia, NOS   98   
-20 Acute myeloid leukemia, NOS   166   
-21 Acute myeloid leukemia, NOS   184   
-22 Acute myeloid leukemia, NOS   144   
-X Acute myeloid leukemia, NOS   157   
-Y Acute myeloid leukemia, NOS   277