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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q23 t(11;19)(q23;p13) Bilineage or biphenotypic leukemia   17  KMT2A/ELL,KMT2A/MLLT1
11q23 t(1;11)(p32;q23) Bilineage or biphenotypic leukemia   KMT2A/EPS15
11q23 t(4;11)(q21;q23) Bilineage or biphenotypic leukemia   27  KMT2A/AFF1,KMT2A+
11q23 t(9;11)(p21;q23) Bilineage or biphenotypic leukemia   KMT2A+
11q23 t(9;11)(p22;q23) Bilineage or biphenotypic leukemia    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
11q14 del(11)(q14) Bilineage or biphenotypic leukemia    
11q23 del(11)(q23) Bilineage or biphenotypic leukemia    
11q23 der(11)t(1;11)(q21;q23) Bilineage or biphenotypic leukemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Bilineage or biphenotypic leukemia   10   
+2 Bilineage or biphenotypic leukemia    
+3 Bilineage or biphenotypic leukemia    
+4 Bilineage or biphenotypic leukemia   21   
+5 Bilineage or biphenotypic leukemia    
+6 Bilineage or biphenotypic leukemia   20   
+7 Bilineage or biphenotypic leukemia    
+8 Bilineage or biphenotypic leukemia   34   
+9 Bilineage or biphenotypic leukemia    
+10 Bilineage or biphenotypic leukemia   10   
+11 Bilineage or biphenotypic leukemia    
+12 Bilineage or biphenotypic leukemia    
+13 Bilineage or biphenotypic leukemia   13   
+14 Bilineage or biphenotypic leukemia    
+15 Bilineage or biphenotypic leukemia    
+17 Bilineage or biphenotypic leukemia    
+18 Bilineage or biphenotypic leukemia   10   
+19 Bilineage or biphenotypic leukemia   21   
+20 Bilineage or biphenotypic leukemia    
+21 Bilineage or biphenotypic leukemia   32   
+22 Bilineage or biphenotypic leukemia   11   
+X Bilineage or biphenotypic leukemia   12   
+Y Bilineage or biphenotypic leukemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Bilineage or biphenotypic leukemia    
-2 Bilineage or biphenotypic leukemia    
-3 Bilineage or biphenotypic leukemia    
-4 Bilineage or biphenotypic leukemia    
-5 Bilineage or biphenotypic leukemia   11   
-6 Bilineage or biphenotypic leukemia    
-7 Bilineage or biphenotypic leukemia   50   
-8 Bilineage or biphenotypic leukemia    
-9 Bilineage or biphenotypic leukemia    
-10 Bilineage or biphenotypic leukemia    
-11 Bilineage or biphenotypic leukemia    
-12 Bilineage or biphenotypic leukemia   11   
-13 Bilineage or biphenotypic leukemia   13   
-14 Bilineage or biphenotypic leukemia    
-15 Bilineage or biphenotypic leukemia    
-16 Bilineage or biphenotypic leukemia    
-17 Bilineage or biphenotypic leukemia   14   
-18 Bilineage or biphenotypic leukemia    
-19 Bilineage or biphenotypic leukemia    
-20 Bilineage or biphenotypic leukemia    
-21 Bilineage or biphenotypic leukemia    
-22 Bilineage or biphenotypic leukemia    
-X Bilineage or biphenotypic leukemia   12   
-Y Bilineage or biphenotypic leukemia