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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
2q11 t(2;11;22)(q11;q24;q12) Ewing sarcoma Skeleton  
7p22 t(7;22)(p22;q12) Ewing sarcoma Skeleton  
11q23 t(11;22)(q23;q11) Ewing sarcoma Unknown site  
11q23 t(11;22)(q23;q11) Ewing sarcoma Skeleton  
11q24 t(11;22)(q24;q11) Ewing sarcoma Skeleton  
11q24 t(11;22)(q24;q11) Ewing sarcoma Soft tissue  
11q24 t(11;22)(q24;q12) Ewing sarcoma Lung EWSR1/FLI1
11q24 t(11;22)(q24;q12) Ewing sarcoma Unknown site EWSR1/FLI1,EWSR1+
11q24 t(11;22)(q24;q12) Ewing sarcoma Intraabdominal  
11q24 t(11;22)(q24;q12) Ewing sarcoma Brain EWSR1/FLI1
11q24 t(11;22)(q24;q12) Ewing sarcoma Pancreas EWSR1/FLI1
11q24 t(11;22)(q24;q12) Ewing sarcoma Intrathoracal  
11q24 t(11;22)(q24;q12) Ewing sarcoma Kidney EWSR1/FLI1
11q24 t(11;22)(q24;q12) Ewing sarcoma Soft tissue 26  EWSR1/FLI1,EWSR1+
11q24 t(11;22)(q24;q12) Ewing sarcoma Skeleton 229  EWSR1/FLI1,EWSR1+
11q24 t(11;22)(q24;q13) Ewing sarcoma Skeleton  
11q24 t(2;11;22)(q11;q24;q12) Ewing sarcoma Skeleton  
16p11 t(16;21)(p11;q22) Ewing sarcoma Skeleton FUS/ERG
21q22 ins(21;22)(q22;q12q12) Ewing sarcoma Skeleton EWSR1/ERG
21q22 t(16;21)(p11;q22) Ewing sarcoma Skeleton FUS/ERG
22q11 t(11;22)(q23;q11) Ewing sarcoma Unknown site  
22q11 t(11;22)(q23;q11) Ewing sarcoma Skeleton  
22q11 t(11;22)(q24;q11) Ewing sarcoma Skeleton  
22q11 t(11;22)(q24;q11) Ewing sarcoma Soft tissue  
22q12 ins(21;22)(q22;q12q12) Ewing sarcoma Skeleton EWSR1/ERG
22q12 ins(21;22)(q22;q12q12) Ewing sarcoma Skeleton EWSR1/ERG
22q12 t(11;22)(q24;q12) Ewing sarcoma Unknown site EWSR1/FLI1,EWSR1+
22q12 t(11;22)(q24;q12) Ewing sarcoma Soft tissue 26  EWSR1/FLI1,EWSR1+
22q12 t(11;22)(q24;q12) Ewing sarcoma Skeleton 229  EWSR1/FLI1,EWSR1+
22q12 t(11;22)(q24;q12) Ewing sarcoma Brain EWSR1/FLI1
22q12 t(11;22)(q24;q12) Ewing sarcoma Kidney EWSR1/FLI1
22q12 t(11;22)(q24;q12) Ewing sarcoma Intraabdominal  
22q12 t(11;22)(q24;q12) Ewing sarcoma Lung EWSR1/FLI1
22q12 t(11;22)(q24;q12) Ewing sarcoma Intrathoracal  
22q12 t(11;22)(q24;q12) Ewing sarcoma Pancreas EWSR1/FLI1
22q12 t(2;11;22)(q11;q24;q12) Ewing sarcoma Skeleton  
22q12 t(7;22)(p22;q12) Ewing sarcoma Skeleton  
22q13 t(11;22)(q24;q13) Ewing sarcoma Skeleton  

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p21 del(1)(p21) Ewing sarcoma Skeleton  
1p31 del(1)(p31) Ewing sarcoma Skeleton  
1p34 add(1)(p34) Ewing sarcoma Skeleton  
1p36 del(1)(p36) Ewing sarcoma Skeleton  
1q10 i(1)(q10) Ewing sarcoma Soft tissue  
1q10 i(1)(q10) Ewing sarcoma Skeleton  
1q10 i(1)(q10) Ewing sarcoma Kidney  
1q11 der(16)t(1;16)(q11;q11) Ewing sarcoma Skeleton  
1q12 der(16)t(1;16)(q12;q11) Ewing sarcoma Skeleton 10   
1q12 der(16)t(1;16)(q12;q12) Ewing sarcoma Skeleton  
1q21 del(1)(q21) Ewing sarcoma Skeleton  
1q21 der(16)t(1;16)(q21;q13) Ewing sarcoma Skeleton 11   
1q32 del(1)(q32) Ewing sarcoma Skeleton  
3q21 del(3)(q21) Ewing sarcoma Skeleton  
4q31 del(4)(q31) Ewing sarcoma Skeleton  
5q14 der(19)t(5;19)(q14;p13) Ewing sarcoma Unknown site  
5q15 del(5)(q15q33) Ewing sarcoma Skeleton  
5q33 del(5)(q15q33) Ewing sarcoma Skeleton  
6q23 del(6)(q23) Ewing sarcoma Skeleton  
8p21 del(8)(p21) Ewing sarcoma Skeleton  
8q10 i(8)(q10) Ewing sarcoma Skeleton  
8q24 add(8)(q24) Ewing sarcoma Skeleton  
9p11 add(9)(p11) Ewing sarcoma Skeleton  
9p21 del(9)(p21) Ewing sarcoma Skeleton  
11q21 del(11)(q21) Ewing sarcoma Skeleton  
11q23 del(11)(q23) Ewing sarcoma Skeleton  
11q24 add(11)(q24) Ewing sarcoma Skeleton  
11q24 der(11)t(11;22)(q24;q12) Ewing sarcoma Skeleton  
13p11 add(13)(p11) Ewing sarcoma Skeleton  
15p11 add(15)(p11) Ewing sarcoma Skeleton  
15q26 add(15)(q26) Ewing sarcoma Skeleton  
16q11 der(16)t(1;16)(q11;q11) Ewing sarcoma Skeleton  
16q11 der(16)t(1;16)(q12;q11) Ewing sarcoma Skeleton 10   
16q12 add(16)(q12) Ewing sarcoma Skeleton  
16q12 der(16)t(1;16)(q12;q12) Ewing sarcoma Skeleton  
16q13 der(16)t(1;16)(q21;q13) Ewing sarcoma Skeleton 11   
17p13 add(17)(p13) Ewing sarcoma Skeleton  
17q10 i(17)(q10) Ewing sarcoma Skeleton  
19p13 add(19)(p13) Ewing sarcoma Skeleton  
19p13 der(19)t(5;19)(q14;p13) Ewing sarcoma Unknown site  
19q13 add(19)(q13) Ewing sarcoma Skeleton  
21p11 add(21)(p11) Ewing sarcoma Skeleton  
21q21 add(21)(q21) Ewing sarcoma Skeleton  
21q22 add(21)(q22) Ewing sarcoma Soft tissue  
22q11 del(22)(q11) Ewing sarcoma Unknown site  
22q11 del(22)(q11) Ewing sarcoma Skeleton  
22q12 add(22)(q12) Ewing sarcoma Skeleton  
22q12 del(22)(q12) Ewing sarcoma Soft tissue  
22q12 del(22)(q12) Ewing sarcoma Skeleton  
22q12 der(11)t(11;22)(q24;q12) Ewing sarcoma Skeleton  
Xp11 add(X)(p11) Ewing sarcoma Skeleton  
Xp22 add(X)(p22) Ewing sarcoma Skeleton  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Ewing sarcoma Skeleton 15   
+1 Ewing sarcoma Unknown site  
+2 Ewing sarcoma Intraabdominal  
+2 Ewing sarcoma Skeleton 41   
+2 Ewing sarcoma Soft tissue  
+2 Ewing sarcoma Unknown site  
+3 Ewing sarcoma Skeleton 11   
+4 Ewing sarcoma Lung  
+4 Ewing sarcoma Skeleton 26   
+4 Ewing sarcoma Unknown site  
+5 Ewing sarcoma Intrathoracal  
+5 Ewing sarcoma Skeleton 29   
+5 Ewing sarcoma Soft tissue  
+5 Ewing sarcoma Unknown site  
+6 Ewing sarcoma Skeleton 13   
+6 Ewing sarcoma Soft tissue  
+7 Ewing sarcoma Unknown site  
+7 Ewing sarcoma Skeleton 29   
+8 Ewing sarcoma Lung  
+8 Ewing sarcoma Intrathoracal  
+8 Ewing sarcoma Intraabdominal  
+8 Ewing sarcoma Kidney  
+8 Ewing sarcoma Brain  
+8 Ewing sarcoma Skeleton 121   
+8 Ewing sarcoma Soft tissue 17   
+8 Ewing sarcoma Unknown site  
+9 Ewing sarcoma Skeleton 18   
+9 Ewing sarcoma Soft tissue  
+9 Ewing sarcoma Unknown site  
+10 Ewing sarcoma Skeleton 16   
+10 Ewing sarcoma Soft tissue  
+11 Ewing sarcoma Soft tissue  
+11 Ewing sarcoma Skeleton 11   
+12 Ewing sarcoma Lung  
+12 Ewing sarcoma Intrathoracal  
+12 Ewing sarcoma Kidney  
+12 Ewing sarcoma Brain  
+12 Ewing sarcoma Skeleton 66   
+12 Ewing sarcoma Soft tissue  
+12 Ewing sarcoma Unknown site  
+13 Ewing sarcoma Skeleton 14   
+14 Ewing sarcoma Lung  
+14 Ewing sarcoma Skeleton 23   
+14 Ewing sarcoma Soft tissue  
+14 Ewing sarcoma Unknown site  
+15 Ewing sarcoma Skeleton 23   
+15 Ewing sarcoma Soft tissue  
+15 Ewing sarcoma Unknown site  
+16 Ewing sarcoma Skeleton  
+16 Ewing sarcoma Soft tissue  
+17 Ewing sarcoma Skeleton  
+17 Ewing sarcoma Soft tissue  
+18 Ewing sarcoma Lung  
+18 Ewing sarcoma Kidney  
+18 Ewing sarcoma Skeleton 31   
+18 Ewing sarcoma Soft tissue  
+18 Ewing sarcoma Unknown site  
+19 Ewing sarcoma Skeleton  
+20 Ewing sarcoma Unknown site  
+20 Ewing sarcoma Soft tissue  
+20 Ewing sarcoma Skeleton 36   
+20 Ewing sarcoma Lung  
+21 Ewing sarcoma Soft tissue  
+21 Ewing sarcoma Skeleton 28   
+22 Ewing sarcoma Skeleton  
+X Ewing sarcoma Skeleton 10   
+Y Ewing sarcoma Skeleton  

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Ewing sarcoma Skeleton  
-2 Ewing sarcoma Skeleton  
-3 Ewing sarcoma Skeleton 10   
-4 Ewing sarcoma Skeleton 10   
-4 Ewing sarcoma Unknown site  
-5 Ewing sarcoma Skeleton 12   
-5 Ewing sarcoma Unknown site  
-6 Ewing sarcoma Skeleton 11   
-7 Ewing sarcoma Soft tissue  
-7 Ewing sarcoma Unknown site  
-7 Ewing sarcoma Skeleton 13   
-8 Ewing sarcoma Skeleton  
-9 Ewing sarcoma Skeleton 19   
-9 Ewing sarcoma Soft tissue  
-10 Ewing sarcoma Skeleton 25   
-11 Ewing sarcoma Soft tissue  
-11 Ewing sarcoma Unknown site  
-11 Ewing sarcoma Skeleton 11   
-12 Ewing sarcoma Skeleton  
-13 Ewing sarcoma Skeleton 12   
-14 Ewing sarcoma Skeleton 13   
-14 Ewing sarcoma Soft tissue  
-15 Ewing sarcoma Skeleton  
-15 Ewing sarcoma Soft tissue  
-15 Ewing sarcoma Unknown site  
-16 Ewing sarcoma Skeleton 22   
-17 Ewing sarcoma Skeleton 20   
-17 Ewing sarcoma Soft tissue  
-18 Ewing sarcoma Skeleton 11   
-18 Ewing sarcoma Soft tissue  
-19 Ewing sarcoma Skeleton 12   
-20 Ewing sarcoma Unknown site  
-20 Ewing sarcoma Skeleton  
-21 Ewing sarcoma Skeleton 12   
-22 Ewing sarcoma Soft tissue  
-22 Ewing sarcoma Unknown site  
-22 Ewing sarcoma Skeleton 17   
-X Ewing sarcoma Skeleton 11   
-X Ewing sarcoma Soft tissue  
-Y Ewing sarcoma Skeleton