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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q11 t(1;6)(q11;q11) Malignant melanoma Skin  
1q12 t(1;19)(q12;p13) Malignant melanoma Skin  
1q21 t(1;14)(q21;q32) Malignant melanoma Skin  
6q11 t(1;6)(q11;q11) Malignant melanoma Skin  
14q32 t(1;14)(q21;q32) Malignant melanoma Skin  
19p13 t(1;19)(q12;p13) Malignant melanoma Skin  

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p11 del(1)(p11) Malignant melanoma Skin  
1p13 del(1)(p13) Malignant melanoma Skin  
1p22 del(1)(p22) Malignant melanoma Skin  
1q10 i(1)(q10) Malignant melanoma Skin  
1q11 del(1)(q11) Malignant melanoma Skin  
1q32 del(1)(q32) Malignant melanoma Skin  
1q42 del(1)(q42) Malignant melanoma Skin  
2p11 del(2)(p11) Malignant melanoma Skin  
2p21 del(2)(p21) Malignant melanoma Skin  
2q11 del(2)(q11) Malignant melanoma Skin  
3p14 del(3)(p14p22) Malignant melanoma Skin  
3p22 del(3)(p14p22) Malignant melanoma Skin  
3p25 add(3)(p25) Malignant melanoma Skin  
4q21 del(4)(q21) Malignant melanoma Skin  
6p10 i(6)(p10) Malignant melanoma Skin  
6p21 del(6)(p21) Malignant melanoma Skin  
6q13 del(6)(q13) Malignant melanoma Skin  
6q14 del(6)(q14) Malignant melanoma Skin  
6q15 del(6)(q15) Malignant melanoma Skin  
6q21 del(6)(q21) Malignant melanoma Skin  
6q23 add(6)(q23) Malignant melanoma Skin  
7p11 der(7)t(7;9)(p11;q11) Malignant melanoma Skin  
7q10 i(7)(q10) Malignant melanoma Skin  
8p21 del(8)(p21) Malignant melanoma Skin  
8q10 i(8)(q10) Malignant melanoma Skin  
9p11 del(9)(p11) Malignant melanoma Skin  
9p11 der(9)del(9)(p11)del(9)(q22) Malignant melanoma Skin  
9p21 del(9)(p21) Malignant melanoma Skin MTAP/CDKN2B-AS1
9p22 del(9)(p22) Malignant melanoma Skin  
9q11 der(7)t(7;9)(p11;q11) Malignant melanoma Skin  
9q22 der(9)del(9)(p11)del(9)(q22) Malignant melanoma Skin  
11p15 add(11)(p15) Malignant melanoma Skin  
11q23 del(11)(q23) Malignant melanoma Skin  
12q21 add(12)(q21) Malignant melanoma Skin  
16q24 del(16)(q24) Malignant melanoma Skin  
17p13 del(17)(p13) Malignant melanoma Skin  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Malignant melanoma Skin  
+2 Malignant melanoma Skin  
+3 Malignant melanoma Skin  
+4 Malignant melanoma Skin  
+5 Malignant melanoma Skin  
+6 Malignant melanoma Skin 11   
+7 Malignant melanoma Skin 21   
+8 Malignant melanoma Skin 13   
+9 Malignant melanoma Skin  
+10 Malignant melanoma Skin  
+11 Malignant melanoma Skin  
+12 Malignant melanoma Skin  
+13 Malignant melanoma Skin  
+14 Malignant melanoma Skin  
+15 Malignant melanoma Skin  
+16 Malignant melanoma Skin  
+17 Malignant melanoma Skin  
+18 Malignant melanoma Skin  
+19 Malignant melanoma Skin 12   
+20 Malignant melanoma Skin 23   
+21 Malignant melanoma Skin  
+22 Malignant melanoma Skin 11   
+X Malignant melanoma Skin  
+Y Malignant melanoma Skin  

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Malignant melanoma Skin  
-2 Malignant melanoma Skin 14   
-3 Malignant melanoma Skin 11   
-4 Malignant melanoma Skin 20   
-5 Malignant melanoma Skin 14   
-6 Malignant melanoma Skin 14   
-7 Malignant melanoma Skin  
-8 Malignant melanoma Skin 15   
-9 Malignant melanoma Skin 16   
-10 Malignant melanoma Skin 36   
-11 Malignant melanoma Skin 19   
-12 Malignant melanoma Skin 21   
-13 Malignant melanoma Skin 19   
-14 Malignant melanoma Skin 20   
-15 Malignant melanoma Skin 22   
-16 Malignant melanoma Skin 22   
-17 Malignant melanoma Skin 17   
-18 Malignant melanoma Skin 16   
-19 Malignant melanoma Skin 14   
-20 Malignant melanoma Skin 14   
-21 Malignant melanoma Skin 24   
-22 Malignant melanoma Skin 19   
-X Malignant melanoma Skin 19   
-Y Malignant melanoma Skin 14