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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
2q13 t(2;3)(q13;p25) Adenocarcinoma Thyroid PAX8/PPARG
3p25 t(2;3)(q13;p25) Adenocarcinoma Thyroid PAX8/PPARG
7q35 t(7;10)(q35;q21) Adenocarcinoma Thyroid  
10q11 inv(10)(q11q21) Adenocarcinoma Thyroid CCDC6/RET
10q21 inv(10)(q11q21) Adenocarcinoma Thyroid CCDC6/RET
10q21 t(7;10)(q35;q21) Adenocarcinoma Thyroid  

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
9p22 add(9)(p22) Adenocarcinoma Thyroid  
10p13 add(10)(p13) Adenocarcinoma Thyroid  
12p11 del(12)(p11) Adenocarcinoma Thyroid  
12q24 add(12)(q24) Adenocarcinoma Thyroid  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+2 Adenocarcinoma Thyroid  
+5 Adenocarcinoma Thyroid  
+6 Adenocarcinoma Thyroid  
+7 Adenocarcinoma Thyroid 23   
+9 Adenocarcinoma Thyroid  
+12 Adenocarcinoma Thyroid  
+13 Adenocarcinoma Thyroid  
+14 Adenocarcinoma Thyroid  
+16 Adenocarcinoma Thyroid  
+17 Adenocarcinoma Thyroid  
+18 Adenocarcinoma Thyroid  
+19 Adenocarcinoma Thyroid  
+20 Adenocarcinoma Thyroid 10   
+21 Adenocarcinoma Thyroid  
+X Adenocarcinoma Thyroid  
+Y Adenocarcinoma Thyroid  

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Adenocarcinoma Thyroid  
-2 Adenocarcinoma Thyroid  
-3 Adenocarcinoma Thyroid  
-4 Adenocarcinoma Thyroid  
-5 Adenocarcinoma Thyroid  
-6 Adenocarcinoma Thyroid  
-7 Adenocarcinoma Thyroid  
-8 Adenocarcinoma Thyroid 11   
-9 Adenocarcinoma Thyroid  
-10 Adenocarcinoma Thyroid  
-11 Adenocarcinoma Thyroid 11   
-12 Adenocarcinoma Thyroid  
-13 Adenocarcinoma Thyroid 11   
-14 Adenocarcinoma Thyroid  
-15 Adenocarcinoma Thyroid  
-16 Adenocarcinoma Thyroid  
-17 Adenocarcinoma Thyroid 11   
-18 Adenocarcinoma Thyroid 12   
-19 Adenocarcinoma Thyroid  
-20 Adenocarcinoma Thyroid  
-21 Adenocarcinoma Thyroid 11   
-22 Adenocarcinoma Thyroid 12   
-X Adenocarcinoma Thyroid  
-Y Adenocarcinoma Thyroid 13