Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Chromosomes
  • Tools
  • Genetic and Physical SNP Maps
  • SNP500Cancer
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
2p23 t(2;8)(p23;q22) Adenoma Salivary gland  
2q13 t(2;3)(q13;p25) Adenoma Thyroid PAX8/PPARG
2q21 t(X;2)(q26;q21) Adenoma Salivary gland  
2q35 t(2;6)(q35;p21) Adenoma Uterus, corpus HMGA1+
3p21 t(3;5)(p21;p15) Adenoma Salivary gland  
3p21 t(3;8)(p21;q12) Adenoma Salivary gland 76  PLAG1+
3p21 t(3;8;9)(p21;q12;p21) Adenoma Salivary gland PLAG1+
3p23 t(3;8)(p23;q12) Adenoma Salivary gland  
3p25 t(2;3)(q13;p25) Adenoma Thyroid PAX8/PPARG
3p25 t(3;8)(p25;q21) Adenoma Salivary gland  
3q29 t(3;8)(q29;q13) Adenoma Salivary gland  
5p13 t(5;8)(p13;q12) Adenoma Salivary gland LIFR/PLAG1,PLAG1+
5p15 t(3;5)(p21;p15) Adenoma Salivary gland  
5p15 t(5;8)(p15;q12) Adenoma Salivary gland PLAG1+
5q13 t(5;19)(q13;q13) Adenoma Thyroid ZNF331+
6p21 t(2;6)(q35;p21) Adenoma Uterus, corpus HMGA1+
6p21 t(6;14)(p21;q24) Adenoma Uterus, corpus  
6p21 t(6;8)(p21;q12) Adenoma Salivary gland  
6q27 t(6;10)(q27;q24) Adenoma Large intestine  
8q12 t(3;8)(p21;q12) Adenoma Salivary gland 76  PLAG1+
8q12 t(3;8)(p23;q12) Adenoma Salivary gland  
8q12 t(3;8;9)(p21;q12;p21) Adenoma Salivary gland PLAG1+
8q12 t(5;8)(p13;q12) Adenoma Salivary gland LIFR/PLAG1,PLAG1+
8q12 t(5;8)(p15;q12) Adenoma Salivary gland PLAG1+
8q12 t(6;8)(p21;q12) Adenoma Salivary gland  
8q12 t(8;10)(q12;q22) Adenoma Salivary gland PLAG1+
8q12 t(8;12)(q12;p13) Adenoma Salivary gland  
8q12 t(8;15)(q12;q26) Adenoma Salivary gland PLAG1+
8q12 t(8;9)(q12;p22) Adenoma Salivary gland PLAG1+
8q12 t(8;9)(q12;p24) Adenoma Salivary gland  
8q13 t(3;8)(q29;q13) Adenoma Salivary gland  
8q21 t(3;8)(p25;q21) Adenoma Salivary gland  
8q22 t(2;8)(p23;q22) Adenoma Salivary gland  
9p21 t(3;8;9)(p21;q12;p21) Adenoma Salivary gland PLAG1+
9p22 t(8;9)(q12;p22) Adenoma Salivary gland PLAG1+
9p24 t(8;9)(q12;p24) Adenoma Salivary gland  
10q22 t(8;10)(q12;q22) Adenoma Salivary gland PLAG1+
10q24 t(6;10)(q27;q24) Adenoma Large intestine  
12p13 t(8;12)(q12;p13) Adenoma Salivary gland  
12q15 inv(12)(q15q24) Adenoma Salivary gland  
12q24 inv(12)(q15q24) Adenoma Salivary gland  
14q24 t(6;14)(p21;q24) Adenoma Uterus, corpus  
15q26 t(8;15)(q12;q26) Adenoma Salivary gland PLAG1+
19q13 t(5;19)(q13;q13) Adenoma Thyroid ZNF331+
Xq26 t(X;2)(q26;q21) Adenoma Salivary gland  

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p34 del(1)(p34) Adenoma Large intestine  
1p35 der(1)t(1;2)(p35;p21) Adenoma Salivary gland  
1p36 del(1)(p36) Adenoma Large intestine  
1q10 i(1)(q10) Adenoma Pituitary  
2p21 der(1)t(1;2)(p35;p21) Adenoma Salivary gland  
2p21 der(2)t(2;3)(p21;q21) Adenoma Salivary gland  
3p21 del(3)(p21) Adenoma Salivary gland  
3q21 der(2)t(2;3)(p21;q21) Adenoma Salivary gland  
3q21 der(3)t(3;8)(q21;q12) Adenoma Salivary gland  
5p10 i(5)(p10) Adenoma Large intestine  
5p14 r(5)(p14q21) Adenoma Salivary gland  
5p15 r(5)(p15q12) Adenoma Salivary gland  
5q12 r(5)(p15q12) Adenoma Salivary gland  
5q21 r(5)(p14q21) Adenoma Salivary gland  
6q25 del(6)(q25) Adenoma Ovary 10   
6q26 del(6)(q26) Adenoma Ovary 11   
6q27 del(6)(q27) Adenoma Ovary  
7p22 add(7)(p22) Adenoma Pituitary  
8p12 add(8)(p12) Adenoma Large intestine  
8p12 del(8)(p12) Adenoma Salivary gland  
8p12 r(8)(p12q12) Adenoma Salivary gland  
8p12 r(8)(p12q12)x1-2 Adenoma Salivary gland  
8p21 del(8)(p21) Adenoma Large intestine  
8p23 r(8)(p23q12) Adenoma Salivary gland  
8q12 der(3)t(3;8)(q21;q12) Adenoma Salivary gland  
8q12 r(8)(p12q12) Adenoma Salivary gland  
8q12 r(8)(p12q12)x1-2 Adenoma Salivary gland  
8q12 r(8)(p23q12) Adenoma Salivary gland  
11q13 del(11)(q13q13) Adenoma Thyroid  
11q13 del(11)(q13q13) Adenoma Thyroid  
12p13 add(12)(p13) Adenoma Pituitary  
12q13 del(12)(q13q14) Adenoma Salivary gland  
12q13 del(12)(q13q15) Adenoma Salivary gland  
12q14 del(12)(q13q14) Adenoma Salivary gland  
12q15 del(12)(q13q15) Adenoma Salivary gland  
13q10 der(13;15)(q10;q10) Adenoma Salivary gland  
13q10 der(13;17)(q10;q10) Adenoma Large intestine  
15q10 der(13;15)(q10;q10) Adenoma Salivary gland  
15q22 del(15)(q22) Adenoma Salivary gland  
17q10 der(13;17)(q10;q10) Adenoma Large intestine  
17q10 i(17)(q10) Adenoma Large intestine  
18p10 i(18)(p10) Adenoma Large intestine  
19q13 add(19)(q13) Adenoma Salivary gland  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Adenoma Ovary  
+1 Adenoma Large intestine  
+2 Adenoma Large intestine 10   
+2 Adenoma Ovary  
+3 Adenoma Salivary gland  
+3 Adenoma Large intestine 12   
+3 Adenoma Kidney  
+3 Adenoma Ovary  
+3 Adenoma Pituitary  
+4 Adenoma Large intestine  
+4 Adenoma Ovary  
+4 Adenoma Pituitary  
+4 Adenoma Thyroid 12   
+5 Adenoma Salivary gland  
+5 Adenoma Large intestine 10   
+5 Adenoma Ovary  
+5 Adenoma Pituitary  
+5 Adenoma Thyroid 20   
+6 Adenoma Thyroid  
+6 Adenoma Ovary  
+6 Adenoma Large intestine 10   
+7 Adenoma Salivary gland  
+7 Adenoma Large intestine 69   
+7 Adenoma Kidney 13   
+7 Adenoma Ovary  
+7 Adenoma Pituitary 11   
+7 Adenoma Thyroid 34   
+8 Adenoma Salivary gland 14   
+8 Adenoma Large intestine 15   
+8 Adenoma Ovary  
+8 Adenoma Pituitary  
+8 Adenoma Thyroid  
+9 Adenoma Large intestine 15   
+9 Adenoma Pituitary  
+9 Adenoma Thyroid 12   
+10 Adenoma Ovary  
+10 Adenoma Large intestine  
+11 Adenoma Thyroid  
+11 Adenoma Pituitary  
+11 Adenoma Ovary  
+11 Adenoma Large intestine  
+12 Adenoma Large intestine  
+12 Adenoma Kidney  
+12 Adenoma Ovary 11   
+12 Adenoma Pituitary  
+12 Adenoma Thyroid 29   
+13 Adenoma Large intestine 44   
+13 Adenoma Ovary  
+13 Adenoma Pituitary  
+13 Adenoma Thyroid  
+14 Adenoma Large intestine 12   
+14 Adenoma Ovary  
+14 Adenoma Pituitary  
+14 Adenoma Thyroid  
+15 Adenoma Ovary  
+15 Adenoma Large intestine  
+16 Adenoma Large intestine 10   
+16 Adenoma Kidney  
+16 Adenoma Ovary  
+16 Adenoma Thyroid 14   
+17 Adenoma Large intestine  
+17 Adenoma Kidney 13   
+17 Adenoma Ovary  
+17 Adenoma Pituitary  
+17 Adenoma Thyroid 16   
+18 Adenoma Thyroid  
+19 Adenoma Thyroid  
+19 Adenoma Pituitary  
+19 Adenoma Ovary  
+19 Adenoma Large intestine  
+20 Adenoma Large intestine 31   
+20 Adenoma Ovary  
+20 Adenoma Pituitary  
+20 Adenoma Thyroid 13   
+21 Adenoma Large intestine  
+21 Adenoma Thyroid  
+21 Adenoma Ovary  
+22 Adenoma Thyroid  
+22 Adenoma Pituitary  
+22 Adenoma Ovary  
+22 Adenoma Large intestine  
+X Adenoma Large intestine  
+X Adenoma Ovary  
+X Adenoma Pituitary  
+X Adenoma Thyroid  
+Y Adenoma Large intestine  

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Adenoma Pituitary  
-1 Adenoma Thyroid  
-1 Adenoma Large intestine  
-2 Adenoma Thyroid  
-3 Adenoma Pituitary  
-4 Adenoma Large intestine  
-4 Adenoma Pituitary  
-5 Adenoma Salivary gland  
-5 Adenoma Large intestine  
-5 Adenoma Pituitary  
-6 Adenoma Pituitary  
-6 Adenoma Ovary  
-6 Adenoma Thyroid  
-6 Adenoma Large intestine  
-7 Adenoma Large intestine  
-7 Adenoma Ovary  
-7 Adenoma Pituitary  
-8 Adenoma Salivary gland  
-8 Adenoma Large intestine  
-8 Adenoma Ovary  
-8 Adenoma Pituitary  
-8 Adenoma Thyroid  
-9 Adenoma Ovary  
-9 Adenoma Pituitary  
-10 Adenoma Ovary  
-10 Adenoma Pituitary  
-10 Adenoma Thyroid  
-10 Adenoma Salivary gland  
-10 Adenoma Large intestine  
-11 Adenoma Pituitary  
-11 Adenoma Ovary  
-11 Adenoma Large intestine  
-11 Adenoma Thyroid  
-11 Adenoma Salivary gland  
-12 Adenoma Ovary  
-13 Adenoma Salivary gland  
-13 Adenoma Pituitary  
-13 Adenoma Thyroid  
-14 Adenoma Large intestine  
-14 Adenoma Pituitary  
-15 Adenoma Salivary gland  
-15 Adenoma Large intestine  
-15 Adenoma Ovary  
-15 Adenoma Pituitary  
-15 Adenoma Thyroid  
-16 Adenoma Ovary  
-16 Adenoma Pituitary  
-16 Adenoma Thyroid  
-17 Adenoma Large intestine  
-17 Adenoma Ovary  
-17 Adenoma Pituitary  
-17 Adenoma Thyroid  
-18 Adenoma Thyroid  
-18 Adenoma Pituitary  
-18 Adenoma Salivary gland  
-18 Adenoma Large intestine 21   
-19 Adenoma Pituitary  
-19 Adenoma Ovary  
-19 Adenoma Large intestine  
-19 Adenoma Thyroid  
-19 Adenoma Salivary gland  
-20 Adenoma Large intestine  
-20 Adenoma Ovary 12   
-20 Adenoma Thyroid  
-21 Adenoma Pituitary  
-21 Adenoma Ovary  
-21 Adenoma Large intestine  
-21 Adenoma Thyroid  
-21 Adenoma Salivary gland  
-22 Adenoma Pituitary  
-22 Adenoma Ovary  
-22 Adenoma Large intestine  
-22 Adenoma Thyroid 14   
-22 Adenoma Salivary gland  
-X Adenoma Salivary gland  
-X Adenoma Ovary  
-X Adenoma Pituitary  
-X Adenoma Thyroid  
-Y Adenoma Adrenal  
-Y Adenoma Kidney 10   
-Y Adenoma Pituitary  
-Y Adenoma Salivary gland  
-Y Adenoma Large intestine 10