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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
8p12 t(8;8)(p12;q11) T-prolymphocytic leukemia    
8q11 t(8;8)(p12;q11) T-prolymphocytic leukemia    
11q21 t(11;14)(q21;q32) T-prolymphocytic leukemia    
14q11 inv(14)(q11q32) T-prolymphocytic leukemia   67  TCL1A+,TRA+
14q11 t(14;14)(q11;q32) T-prolymphocytic leukemia   IGH/TRA,TCL1A+,TRA+
14q11 t(X;14)(q28;q11) T-prolymphocytic leukemia   TRA/MTCP1,TRA+
14q32 inv(14)(q11q32) T-prolymphocytic leukemia   67  TCL1A+,TRA+
14q32 t(11;14)(q21;q32) T-prolymphocytic leukemia    
14q32 t(14;14)(q11;q32) T-prolymphocytic leukemia   IGH/TRA,TCL1A+,TRA+
Xq28 t(X;14)(q28;q11) T-prolymphocytic leukemia   TRA/MTCP1,TRA+

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p36 add(1)(p36) T-prolymphocytic leukemia    
1q21 add(1)(q21) T-prolymphocytic leukemia    
3p14 der(6)t(3;6)(p14;q21) T-prolymphocytic leukemia    
3q11 add(3)(q11) T-prolymphocytic leukemia    
5q31 der(10)t(5;10)(q31;q26) T-prolymphocytic leukemia    
6q21 del(6)(q21) T-prolymphocytic leukemia    
6q21 der(6)t(3;6)(p14;q21) T-prolymphocytic leukemia    
6q23 del(6)(q23) T-prolymphocytic leukemia    
7p15 del(7)(p15) T-prolymphocytic leukemia    
7p21 add(7)(p21) T-prolymphocytic leukemia    
7q10 i(7)(q10) T-prolymphocytic leukemia    
7q22 add(7)(q22) T-prolymphocytic leukemia    
8p11 add(8)(p11) T-prolymphocytic leukemia    
8p11 idic(8)(p11) T-prolymphocytic leukemia    
8p12 der(8)t(8;8)(p12;q11) T-prolymphocytic leukemia    
8p21 der(8)t(8;8)(p21;q11) T-prolymphocytic leukemia    
8p21 der(8)t(8;8)(p21;q21) T-prolymphocytic leukemia    
8q10 i(8)(q10) T-prolymphocytic leukemia   44   
8q11 der(8)t(8;8)(p12;q11) T-prolymphocytic leukemia    
8q11 der(8)t(8;8)(p21;q11) T-prolymphocytic leukemia    
8q21 der(8)t(8;8)(p21;q21) T-prolymphocytic leukemia    
9p11 add(9)(p11) T-prolymphocytic leukemia    
9p23 der(9)t(9;9)(p23;q34) T-prolymphocytic leukemia    
9q34 der(9)t(9;9)(p23;q34) T-prolymphocytic leukemia    
10p13 del(10)(p13) T-prolymphocytic leukemia    
10q23 del(10)(q23) T-prolymphocytic leukemia    
10q25 del(10)(q25) T-prolymphocytic leukemia    
10q26 der(10)t(5;10)(q31;q26) T-prolymphocytic leukemia    
11p13 add(11)(p13) T-prolymphocytic leukemia    
11q13 del(11)(q13) T-prolymphocytic leukemia    
11q14 del(11)(q14) T-prolymphocytic leukemia    
11q14 del(11)(q14q23) T-prolymphocytic leukemia    
11q21 del(11)(q21) T-prolymphocytic leukemia    
11q22 del(11)(q22q23) T-prolymphocytic leukemia    
11q23 add(11)(q23) T-prolymphocytic leukemia    
11q23 del(11)(q14q23) T-prolymphocytic leukemia    
11q23 del(11)(q22q23) T-prolymphocytic leukemia    
11q23 del(11)(q23) T-prolymphocytic leukemia    
12p13 add(12)(p13) T-prolymphocytic leukemia    
13q14 dup(13)(q21q14) T-prolymphocytic leukemia    
13q21 dup(13)(q21q14) T-prolymphocytic leukemia    
14p11 add(14)(p11) T-prolymphocytic leukemia    
14q11 del(14)(q11) T-prolymphocytic leukemia    
15p11 add(15)(p11) T-prolymphocytic leukemia    
15q26 add(15)(q26) T-prolymphocytic leukemia    
17p12 add(17)(p12) T-prolymphocytic leukemia    
17q25 add(17)(q25) T-prolymphocytic leukemia    
19p13 add(19)(p13) T-prolymphocytic leukemia    
20p12 dic(20;22)(p12;p11) T-prolymphocytic leukemia    
21p11 add(21)(p11) T-prolymphocytic leukemia    
21p11 der(21)t(21;21)(p11;q21) T-prolymphocytic leukemia    
21p13 add(21)(p13) T-prolymphocytic leukemia    
21q21 der(21)t(21;21)(p11;q21) T-prolymphocytic leukemia    
22p11 add(22)(p11) T-prolymphocytic leukemia    
22p11 dic(20;22)(p12;p11) T-prolymphocytic leukemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+2 T-prolymphocytic leukemia    
+3 T-prolymphocytic leukemia    
+5 T-prolymphocytic leukemia    
+6 T-prolymphocytic leukemia    
+7 T-prolymphocytic leukemia    
+8 T-prolymphocytic leukemia   17   
+10 T-prolymphocytic leukemia    
+12 T-prolymphocytic leukemia    
+13 T-prolymphocytic leukemia    
+14 T-prolymphocytic leukemia    
+15 T-prolymphocytic leukemia    
+18 T-prolymphocytic leukemia    
+20 T-prolymphocytic leukemia    
+21 T-prolymphocytic leukemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 T-prolymphocytic leukemia    
-2 T-prolymphocytic leukemia    
-3 T-prolymphocytic leukemia    
-4 T-prolymphocytic leukemia    
-5 T-prolymphocytic leukemia    
-6 T-prolymphocytic leukemia   13   
-7 T-prolymphocytic leukemia   11   
-8 T-prolymphocytic leukemia   17   
-9 T-prolymphocytic leukemia   13   
-10 T-prolymphocytic leukemia   18   
-11 T-prolymphocytic leukemia   30   
-12 T-prolymphocytic leukemia    
-13 T-prolymphocytic leukemia   22   
-14 T-prolymphocytic leukemia   27   
-15 T-prolymphocytic leukemia   15   
-16 T-prolymphocytic leukemia   13   
-17 T-prolymphocytic leukemia   18   
-18 T-prolymphocytic leukemia   17   
-19 T-prolymphocytic leukemia    
-20 T-prolymphocytic leukemia   12   
-21 T-prolymphocytic leukemia   17   
-22 T-prolymphocytic leukemia   31   
-X T-prolymphocytic leukemia   11   
-Y T-prolymphocytic leukemia   20