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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
3q27 t(3;12)(q27;q13) Nodal marginal zone B-cell lymphoma    
9p13 t(9;14)(p13;q32) Nodal marginal zone B-cell lymphoma    
12q13 t(3;12)(q27;q13) Nodal marginal zone B-cell lymphoma    
14q32 t(14;18)(q32;q21) Nodal marginal zone B-cell lymphoma    
14q32 t(14;19)(q32;q13) Nodal marginal zone B-cell lymphoma   13  IGH/BCL3
14q32 t(9;14)(p13;q32) Nodal marginal zone B-cell lymphoma    
18q21 t(14;18)(q32;q21) Nodal marginal zone B-cell lymphoma    
19q13 t(14;19)(q32;q13) Nodal marginal zone B-cell lymphoma   13  IGH/BCL3

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p36 add(1)(p36) Nodal marginal zone B-cell lymphoma    
1p36 der(1)t(1;1)(p36;q21) Nodal marginal zone B-cell lymphoma    
1q21 der(1)t(1;1)(p36;q21) Nodal marginal zone B-cell lymphoma    
1q21 der(18)t(1;18)(q21;p11) Nodal marginal zone B-cell lymphoma    
3p13 del(3)(p13) Nodal marginal zone B-cell lymphoma    
3p25 add(3)(p25) Nodal marginal zone B-cell lymphoma    
3q11 add(3)(q11) Nodal marginal zone B-cell lymphoma    
3q27 der(3)t(3;12)(q27;q13) Nodal marginal zone B-cell lymphoma    
6q13 del(6)(q13q16) Nodal marginal zone B-cell lymphoma    
6q15 del(6)(q15) Nodal marginal zone B-cell lymphoma    
6q16 del(6)(q13q16) Nodal marginal zone B-cell lymphoma    
8q24 add(8)(q24) Nodal marginal zone B-cell lymphoma    
11q24 del(11)(q24) Nodal marginal zone B-cell lymphoma    
12p13 add(12)(p13) Nodal marginal zone B-cell lymphoma    
12q13 der(3)t(3;12)(q27;q13) Nodal marginal zone B-cell lymphoma    
13q12 del(13)(q12q14) Nodal marginal zone B-cell lymphoma    
13q14 del(13)(q12q14) Nodal marginal zone B-cell lymphoma    
14p11 add(14)(p11) Nodal marginal zone B-cell lymphoma    
14q32 add(14)(q32) Nodal marginal zone B-cell lymphoma    
16p13 add(16)(p13) Nodal marginal zone B-cell lymphoma    
17p11 del(17)(p11) Nodal marginal zone B-cell lymphoma    
18p11 der(18)t(1;18)(q21;p11) Nodal marginal zone B-cell lymphoma    
18q10 i(18)(q10) Nodal marginal zone B-cell lymphoma    
19q13 add(19)(q13) Nodal marginal zone B-cell lymphoma    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+2 Nodal marginal zone B-cell lymphoma    
+3 Nodal marginal zone B-cell lymphoma   19   
+6 Nodal marginal zone B-cell lymphoma    
+7 Nodal marginal zone B-cell lymphoma    
+8 Nodal marginal zone B-cell lymphoma    
+10 Nodal marginal zone B-cell lymphoma    
+11 Nodal marginal zone B-cell lymphoma    
+12 Nodal marginal zone B-cell lymphoma    
+13 Nodal marginal zone B-cell lymphoma    
+15 Nodal marginal zone B-cell lymphoma    
+18 Nodal marginal zone B-cell lymphoma   23   
+21 Nodal marginal zone B-cell lymphoma    
+22 Nodal marginal zone B-cell lymphoma    
+X Nodal marginal zone B-cell lymphoma   10   

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Nodal marginal zone B-cell lymphoma    
-2 Nodal marginal zone B-cell lymphoma    
-6 Nodal marginal zone B-cell lymphoma    
-7 Nodal marginal zone B-cell lymphoma    
-9 Nodal marginal zone B-cell lymphoma    
-13 Nodal marginal zone B-cell lymphoma    
-15 Nodal marginal zone B-cell lymphoma    
-16 Nodal marginal zone B-cell lymphoma    
-18 Nodal marginal zone B-cell lymphoma    
-20 Nodal marginal zone B-cell lymphoma    
-21 Nodal marginal zone B-cell lymphoma    
-22 Nodal marginal zone B-cell lymphoma    
-X Nodal marginal zone B-cell lymphoma    
-Y Nodal marginal zone B-cell lymphoma