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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
8q24 t(8;14)(q24;q32) Lymphoplasmacytic lymphoma    
11q13 t(11;14)(q13;q32) Lymphoplasmacytic lymphoma   CCND1+,IGH+
14q32 t(11;14)(q13;q32) Lymphoplasmacytic lymphoma   CCND1+,IGH+
14q32 t(8;14)(q24;q32) Lymphoplasmacytic lymphoma    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
6p22 del(6)(p22) Lymphoplasmacytic lymphoma    
7q31 del(7)(q31q35) Lymphoplasmacytic lymphoma    
7q35 del(7)(q31q35) Lymphoplasmacytic lymphoma    
9p13 del(9)(p13) Lymphoplasmacytic lymphoma    
11q22 del(11)(q22) Lymphoplasmacytic lymphoma    
13q12 del(13)(q12) Lymphoplasmacytic lymphoma    
14q32 add(14)(q32) Lymphoplasmacytic lymphoma    
17p11 add(17)(p11) Lymphoplasmacytic lymphoma    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+3 Lymphoplasmacytic lymphoma    
+7 Lymphoplasmacytic lymphoma    
+8 Lymphoplasmacytic lymphoma    
+12 Lymphoplasmacytic lymphoma   20   
+18 Lymphoplasmacytic lymphoma    
+20 Lymphoplasmacytic lymphoma    
+21 Lymphoplasmacytic lymphoma    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-6 Lymphoplasmacytic lymphoma    
-8 Lymphoplasmacytic lymphoma    
-10 Lymphoplasmacytic lymphoma    
-15 Lymphoplasmacytic lymphoma    
-17 Lymphoplasmacytic lymphoma    
-19 Lymphoplasmacytic lymphoma    
-22 Lymphoplasmacytic lymphoma    
-Y Lymphoplasmacytic lymphoma