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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
2p12 t(2;8)(p12;q24) B-prolymphocytic leukemia    
6q15 t(6;12)(q15;p13) B-prolymphocytic leukemia    
8q24 t(2;8)(p12;q24) B-prolymphocytic leukemia    
8q24 t(8;14)(q24;q32) B-prolymphocytic leukemia   IGH/MYC
8q24 t(8;22)(q24;q11) B-prolymphocytic leukemia    
11q13 t(11;14)(q13;q32) B-prolymphocytic leukemia   16  IGH/CCND1
12p13 t(6;12)(q15;p13) B-prolymphocytic leukemia    
14q32 t(11;14)(q13;q32) B-prolymphocytic leukemia   16  IGH/CCND1
14q32 t(8;14)(q24;q32) B-prolymphocytic leukemia   IGH/MYC
22q11 t(8;22)(q24;q11) B-prolymphocytic leukemia    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p36 add(1)(p36) B-prolymphocytic leukemia    
1q32 del(1)(q32) B-prolymphocytic leukemia    
2q37 add(2)(q37) B-prolymphocytic leukemia    
3p13 del(3)(p13) B-prolymphocytic leukemia    
3q11 add(3)(q11) B-prolymphocytic leukemia    
6q21 del(6)(q21) B-prolymphocytic leukemia    
7p22 add(7)(p22) B-prolymphocytic leukemia    
7q31 del(7)(q31) B-prolymphocytic leukemia    
7q32 del(7)(q32) B-prolymphocytic leukemia    
8p11 add(8)(p11) B-prolymphocytic leukemia    
10q24 add(10)(q24) B-prolymphocytic leukemia    
10q26 add(10)(q26) B-prolymphocytic leukemia    
11p15 add(11)(p15) B-prolymphocytic leukemia    
12p12 add(12)(p12) B-prolymphocytic leukemia    
12p13 del(12)(p13) B-prolymphocytic leukemia    
13q14 del(13)(q14) B-prolymphocytic leukemia    
14q32 add(14)(q32) B-prolymphocytic leukemia    
15p13 add(15)(p13) B-prolymphocytic leukemia    
16p13 add(16)(p13) B-prolymphocytic leukemia    
17p11 del(17)(p11) B-prolymphocytic leukemia    
17p12 add(17)(p12) B-prolymphocytic leukemia    
17p13 add(17)(p13) B-prolymphocytic leukemia    
18q23 add(18)(q23) B-prolymphocytic leukemia    
19p13 add(19)(p13) B-prolymphocytic leukemia    
20q13 add(20)(q13) B-prolymphocytic leukemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+3 B-prolymphocytic leukemia   11   
+5 B-prolymphocytic leukemia    
+12 B-prolymphocytic leukemia   19   
+15 B-prolymphocytic leukemia    
+18 B-prolymphocytic leukemia    
+20 B-prolymphocytic leukemia    
+21 B-prolymphocytic leukemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-2 B-prolymphocytic leukemia    
-3 B-prolymphocytic leukemia    
-6 B-prolymphocytic leukemia    
-7 B-prolymphocytic leukemia    
-8 B-prolymphocytic leukemia    
-9 B-prolymphocytic leukemia    
-10 B-prolymphocytic leukemia    
-11 B-prolymphocytic leukemia    
-12 B-prolymphocytic leukemia    
-13 B-prolymphocytic leukemia    
-14 B-prolymphocytic leukemia    
-15 B-prolymphocytic leukemia    
-17 B-prolymphocytic leukemia   21   
-18 B-prolymphocytic leukemia    
-19 B-prolymphocytic leukemia    
-20 B-prolymphocytic leukemia    
-21 B-prolymphocytic leukemia    
-22 B-prolymphocytic leukemia    
-X B-prolymphocytic leukemia    
-Y B-prolymphocytic leukemia   14