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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
6p21 t(6;14)(p21;q32) Plasma cell leukemia   IGH/CCND3
8q24 t(8;14)(q24;q32) Plasma cell leukemia   IGH/MYC
11q13 t(11;14)(q13;q32) Plasma cell leukemia   24  IGH/CCND1,IGH+
11q23 t(11;14)(q23;q32) Plasma cell leukemia    
14q32 t(11;14)(q13;q32) Plasma cell leukemia   24  IGH/CCND1,IGH+
14q32 t(11;14)(q23;q32) Plasma cell leukemia    
14q32 t(14;16)(q32;q23) Plasma cell leukemia    
14q32 t(6;14)(p21;q32) Plasma cell leukemia   IGH/CCND3
14q32 t(8;14)(q24;q32) Plasma cell leukemia   IGH/MYC
16q23 t(14;16)(q32;q23) Plasma cell leukemia    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p11 add(1)(p11) Plasma cell leukemia    
1p13 del(1)(p13) Plasma cell leukemia    
1p13 del(1)(p13p31) Plasma cell leukemia    
1p31 del(1)(p13p31) Plasma cell leukemia    
1p32 add(1)(p32) Plasma cell leukemia    
1p32 del(1)(p32) Plasma cell leukemia    
1q10 der(1;16)(q10;p10) Plasma cell leukemia    
1q10 der(1;17)(q10;q10) Plasma cell leukemia    
1q10 der(1;8)(q10;q10) Plasma cell leukemia    
1q10 i(1)(q10) Plasma cell leukemia    
1q21 del(1)(q21) Plasma cell leukemia    
1q21 dup(1)(q21q32) Plasma cell leukemia    
1q32 dup(1)(q21q32) Plasma cell leukemia    
2q37 add(2)(q37) Plasma cell leukemia    
5p13 del(5)(p13) Plasma cell leukemia    
5q31 add(5)(q31) Plasma cell leukemia    
6q15 del(6)(q15) Plasma cell leukemia    
6q21 del(6)(q21) Plasma cell leukemia    
6q22 del(6)(q22) Plasma cell leukemia    
7p22 add(7)(p22) Plasma cell leukemia    
8q10 der(1;8)(q10;q10) Plasma cell leukemia    
8q10 i(8)(q10) Plasma cell leukemia    
8q11 add(8)(q11) Plasma cell leukemia    
9p24 add(9)(p24) Plasma cell leukemia    
11p15 add(11)(p15) Plasma cell leukemia    
11q13 del(11)(q13) Plasma cell leukemia    
11q13 der(11)t(11;14)(q13;q32) Plasma cell leukemia    
11q13 der(14)t(11;14)(q13;q32) Plasma cell leukemia    
12p13 add(12)(p13) Plasma cell leukemia    
13q13 del(13)(q13) Plasma cell leukemia    
13q14 del(13)(q14) Plasma cell leukemia    
14q32 add(14)(q32) Plasma cell leukemia   15   
14q32 der(11)t(11;14)(q13;q32) Plasma cell leukemia    
14q32 der(14)t(11;14)(q13;q32) Plasma cell leukemia    
15q26 add(15)(q26) Plasma cell leukemia    
16p10 der(1;16)(q10;p10) Plasma cell leukemia    
16q22 add(16)(q22) Plasma cell leukemia    
16q22 del(16)(q22) Plasma cell leukemia    
17p12 del(17)(p12) Plasma cell leukemia    
17q10 der(1;17)(q10;q10) Plasma cell leukemia    
17q10 i(17)(q10) Plasma cell leukemia    
17q25 add(17)(q25) Plasma cell leukemia    
18q23 add(18)(q23) Plasma cell leukemia    
19q13 add(19)(q13) Plasma cell leukemia    
20q13 add(20)(q13) Plasma cell leukemia    
22q11 del(22)(q11) Plasma cell leukemia    
22q13 add(22)(q13) Plasma cell leukemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Plasma cell leukemia    
+2 Plasma cell leukemia    
+3 Plasma cell leukemia   16   
+4 Plasma cell leukemia    
+5 Plasma cell leukemia    
+6 Plasma cell leukemia    
+7 Plasma cell leukemia   15   
+8 Plasma cell leukemia    
+9 Plasma cell leukemia   10   
+10 Plasma cell leukemia    
+11 Plasma cell leukemia   13   
+12 Plasma cell leukemia    
+13 Plasma cell leukemia    
+14 Plasma cell leukemia    
+15 Plasma cell leukemia    
+17 Plasma cell leukemia    
+18 Plasma cell leukemia   13   
+19 Plasma cell leukemia   14   
+20 Plasma cell leukemia    
+21 Plasma cell leukemia   18   
+22 Plasma cell leukemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Plasma cell leukemia   17   
-2 Plasma cell leukemia    
-3 Plasma cell leukemia    
-4 Plasma cell leukemia   10   
-5 Plasma cell leukemia   10   
-6 Plasma cell leukemia    
-7 Plasma cell leukemia    
-8 Plasma cell leukemia   27   
-9 Plasma cell leukemia    
-10 Plasma cell leukemia   14   
-11 Plasma cell leukemia   10   
-12 Plasma cell leukemia   10   
-13 Plasma cell leukemia   68   
-14 Plasma cell leukemia   26   
-15 Plasma cell leukemia   18   
-16 Plasma cell leukemia   28   
-17 Plasma cell leukemia   18   
-18 Plasma cell leukemia   18   
-19 Plasma cell leukemia    
-20 Plasma cell leukemia   18   
-21 Plasma cell leukemia   16   
-22 Plasma cell leukemia   23   
-X Plasma cell leukemia   30   
-Y Plasma cell leukemia   17