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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p36 t(1;13)(p36;q14) Refractory anemia with excess blasts-2    
1p36 t(1;3)(p36;q21) Refractory anemia with excess blasts-2   RPN1/PRDM16
1p36 t(1;7)(p36;q32) Refractory anemia with excess blasts-2    
2p21 t(2;11)(p21;q23) Refractory anemia with excess blasts-2    
3q21 inv(3)(q21q26) Refractory anemia with excess blasts-2    
3q21 t(1;3)(p36;q21) Refractory anemia with excess blasts-2   RPN1/PRDM16
3q21 t(3;3)(q21;q26) Refractory anemia with excess blasts-2    
3q25 t(3;5)(q25;q35) Refractory anemia with excess blasts-2   NPM1/MLF1
3q26 inv(3)(q21q26) Refractory anemia with excess blasts-2    
3q26 t(3;21)(q26;q22) Refractory anemia with excess blasts-2    
3q26 t(3;3)(q21;q26) Refractory anemia with excess blasts-2    
5q35 t(3;5)(q25;q35) Refractory anemia with excess blasts-2   NPM1/MLF1
6p23 t(6;9)(p23;q34) Refractory anemia with excess blasts-2    
7q32 t(1;7)(p36;q32) Refractory anemia with excess blasts-2    
8q22 t(8;21)(q22;q22) Refractory anemia with excess blasts-2    
9q34 t(6;9)(p23;q34) Refractory anemia with excess blasts-2    
9q34 t(9;22)(q34;q11) Refractory anemia with excess blasts-2   BCR+
11q23 t(2;11)(p21;q23) Refractory anemia with excess blasts-2    
13q14 t(1;13)(p36;q14) Refractory anemia with excess blasts-2    
16p13 inv(16)(p13q22) Refractory anemia with excess blasts-2    
16q22 inv(16)(p13q22) Refractory anemia with excess blasts-2    
21q22 t(3;21)(q26;q22) Refractory anemia with excess blasts-2    
21q22 t(8;21)(q22;q22) Refractory anemia with excess blasts-2    
22q11 t(9;22)(q34;q11) Refractory anemia with excess blasts-2   BCR+

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p22 del(1)(p22) Refractory anemia with excess blasts-2    
1p36 add(1)(p36) Refractory anemia with excess blasts-2    
1q10 der(1;7)(q10;p10) Refractory anemia with excess blasts-2    
1q21 der(Y)t(Y;1)(q12;q21) Refractory anemia with excess blasts-2    
1q31 del(1)(q31) Refractory anemia with excess blasts-2    
2q21 add(2)(q21) Refractory anemia with excess blasts-2    
4p14 del(4)(p14) Refractory anemia with excess blasts-2    
4q21 add(4)(q21) Refractory anemia with excess blasts-2    
4q31 del(4)(q31) Refractory anemia with excess blasts-2    
5p10 der(5;17)(p10;q10) Refractory anemia with excess blasts-2    
5p14 add(5)(p14) Refractory anemia with excess blasts-2    
5q11 del(5)(q11q33) Refractory anemia with excess blasts-2    
5q12 del(5)(q12q33) Refractory anemia with excess blasts-2    
5q12 del(5)(q12q34) Refractory anemia with excess blasts-2    
5q13 del(5)(q13) Refractory anemia with excess blasts-2    
5q13 del(5)(q13q31) Refractory anemia with excess blasts-2    
5q13 del(5)(q13q33) Refractory anemia with excess blasts-2   19   
5q13 del(5)(q13q34) Refractory anemia with excess blasts-2    
5q14 del(5)(q14) Refractory anemia with excess blasts-2    
5q14 del(5)(q14q34) Refractory anemia with excess blasts-2    
5q15 del(5)(q15q33) Refractory anemia with excess blasts-2    
5q22 del(5)(q22q33) Refractory anemia with excess blasts-2    
5q23 del(5)(q23q33) Refractory anemia with excess blasts-2    
5q23 del(5)(q23q34) Refractory anemia with excess blasts-2    
5q31 del(5)(q13q31) Refractory anemia with excess blasts-2    
5q31 del(5)(q31q34) Refractory anemia with excess blasts-2    
5q33 del(5)(q11q33) Refractory anemia with excess blasts-2    
5q33 del(5)(q12q33) Refractory anemia with excess blasts-2    
5q33 del(5)(q13q33) Refractory anemia with excess blasts-2   19   
5q33 del(5)(q15q33) Refractory anemia with excess blasts-2    
5q33 del(5)(q22q33) Refractory anemia with excess blasts-2    
5q33 del(5)(q23q33) Refractory anemia with excess blasts-2    
5q34 del(5)(q12q34) Refractory anemia with excess blasts-2    
5q34 del(5)(q13q34) Refractory anemia with excess blasts-2    
5q34 del(5)(q14q34) Refractory anemia with excess blasts-2    
5q34 del(5)(q23q34) Refractory anemia with excess blasts-2    
5q34 del(5)(q31q34) Refractory anemia with excess blasts-2    
7p10 der(1;7)(q10;p10) Refractory anemia with excess blasts-2    
7q21 del(7)(q21) Refractory anemia with excess blasts-2    
7q22 del(7)(q22) Refractory anemia with excess blasts-2    
11p15 add(11)(p15) Refractory anemia with excess blasts-2    
11q10 i(11)(q10) Refractory anemia with excess blasts-2    
11q14 del(11)(q14) Refractory anemia with excess blasts-2    
11q14 del(11)(q14q23) Refractory anemia with excess blasts-2    
11q23 del(11)(q14q23) Refractory anemia with excess blasts-2    
12p11 add(12)(p11) Refractory anemia with excess blasts-2    
12p12 del(12)(p12) Refractory anemia with excess blasts-2    
12p12 del(12)(p12p13) Refractory anemia with excess blasts-2    
12p13 del(12)(p12p13) Refractory anemia with excess blasts-2    
14q10 i(14)(q10) Refractory anemia with excess blasts-2    
15p11 add(15)(p11) Refractory anemia with excess blasts-2    
16p13 add(16)(p13) Refractory anemia with excess blasts-2    
17p11 add(17)(p11) Refractory anemia with excess blasts-2    
17p11 dic(17;20)(p11;q11) Refractory anemia with excess blasts-2    
17p13 add(17)(p13) Refractory anemia with excess blasts-2    
17p13 del(17)(p13) Refractory anemia with excess blasts-2    
17q10 der(5;17)(p10;q10) Refractory anemia with excess blasts-2    
17q10 i(17)(q10) Refractory anemia with excess blasts-2    
18q22 add(18)(q22) Refractory anemia with excess blasts-2    
19p13 add(19)(p13) Refractory anemia with excess blasts-2    
19q13 add(19)(q13) Refractory anemia with excess blasts-2    
20q11 del(20)(q11) Refractory anemia with excess blasts-2    
20q11 del(20)(q11q13) Refractory anemia with excess blasts-2    
20q11 dic(17;20)(p11;q11) Refractory anemia with excess blasts-2    
20q12 del(20)(q12) Refractory anemia with excess blasts-2    
20q13 del(20)(q11q13) Refractory anemia with excess blasts-2    
21q10 i(21)(q10) Refractory anemia with excess blasts-2    
21q22 add(21)(q22) Refractory anemia with excess blasts-2    
Yq12 der(Y)t(Y;1)(q12;q21) Refractory anemia with excess blasts-2    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Refractory anemia with excess blasts-2   12   
+4 Refractory anemia with excess blasts-2    
+6 Refractory anemia with excess blasts-2    
+8 Refractory anemia with excess blasts-2   54   
+9 Refractory anemia with excess blasts-2    
+10 Refractory anemia with excess blasts-2    
+11 Refractory anemia with excess blasts-2   21   
+12 Refractory anemia with excess blasts-2    
+13 Refractory anemia with excess blasts-2    
+14 Refractory anemia with excess blasts-2    
+15 Refractory anemia with excess blasts-2    
+19 Refractory anemia with excess blasts-2    
+20 Refractory anemia with excess blasts-2    
+21 Refractory anemia with excess blasts-2   12   
+22 Refractory anemia with excess blasts-2    
+Y Refractory anemia with excess blasts-2    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-2 Refractory anemia with excess blasts-2    
-3 Refractory anemia with excess blasts-2   12   
-4 Refractory anemia with excess blasts-2    
-5 Refractory anemia with excess blasts-2   25   
-6 Refractory anemia with excess blasts-2    
-7 Refractory anemia with excess blasts-2   59   
-8 Refractory anemia with excess blasts-2    
-9 Refractory anemia with excess blasts-2    
-10 Refractory anemia with excess blasts-2    
-11 Refractory anemia with excess blasts-2    
-12 Refractory anemia with excess blasts-2   10   
-13 Refractory anemia with excess blasts-2   15   
-14 Refractory anemia with excess blasts-2   11   
-15 Refractory anemia with excess blasts-2    
-16 Refractory anemia with excess blasts-2    
-17 Refractory anemia with excess blasts-2   23   
-18 Refractory anemia with excess blasts-2   23   
-19 Refractory anemia with excess blasts-2    
-20 Refractory anemia with excess blasts-2    
-21 Refractory anemia with excess blasts-2   11   
-22 Refractory anemia with excess blasts-2    
-X Refractory anemia with excess blasts-2    
-Y Refractory anemia with excess blasts-2   15