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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p36 t(1;3)(p36;q21) Refractory anemia with ringed sideroblasts   RPN1/PRDM16
3q21 t(1;3)(p36;q21) Refractory anemia with ringed sideroblasts   RPN1/PRDM16
16p13 inv(16)(p13q22) Refractory anemia with ringed sideroblasts   CBFB/MYH11
16q22 inv(16)(p13q22) Refractory anemia with ringed sideroblasts   CBFB/MYH11

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p11 der(1)t(1;7)(p11;p11) Refractory anemia with ringed sideroblasts    
1p13 der(1)t(1;19)(p13;p13) Refractory anemia with ringed sideroblasts    
1q12 der(15)t(1;15)(q12;p11) Refractory anemia with ringed sideroblasts    
5q13 del(5)(q13q31) Refractory anemia with ringed sideroblasts    
5q13 del(5)(q13q33) Refractory anemia with ringed sideroblasts   13   
5q13 del(5)(q13q35) Refractory anemia with ringed sideroblasts    
5q14 del(5)(q14q32) Refractory anemia with ringed sideroblasts    
5q14 del(5)(q14q33) Refractory anemia with ringed sideroblasts    
5q15 del(5)(q15q33) Refractory anemia with ringed sideroblasts    
5q22 del(5)(q22q33) Refractory anemia with ringed sideroblasts    
5q31 del(5)(q13q31) Refractory anemia with ringed sideroblasts    
5q31 del(5)(q31) Refractory anemia with ringed sideroblasts    
5q32 del(5)(q14q32) Refractory anemia with ringed sideroblasts    
5q33 del(5)(q13q33) Refractory anemia with ringed sideroblasts   13   
5q33 del(5)(q14q33) Refractory anemia with ringed sideroblasts    
5q33 del(5)(q15q33) Refractory anemia with ringed sideroblasts    
5q33 del(5)(q22q33) Refractory anemia with ringed sideroblasts    
5q35 del(5)(q13q35) Refractory anemia with ringed sideroblasts    
7p11 der(1)t(1;7)(p11;p11) Refractory anemia with ringed sideroblasts    
7q10 i(7)(q10) Refractory anemia with ringed sideroblasts    
7q21 del(7)(q21q31) Refractory anemia with ringed sideroblasts    
7q22 del(7)(q22) Refractory anemia with ringed sideroblasts    
7q31 del(7)(q21q31) Refractory anemia with ringed sideroblasts    
7q32 del(7)(q32) Refractory anemia with ringed sideroblasts    
11q13 del(11)(q13q24) Refractory anemia with ringed sideroblasts    
11q14 del(11)(q14) Refractory anemia with ringed sideroblasts    
11q14 del(11)(q14q23) Refractory anemia with ringed sideroblasts    
11q21 del(11)(q21) Refractory anemia with ringed sideroblasts    
11q22 del(11)(q22) Refractory anemia with ringed sideroblasts    
11q23 del(11)(q14q23) Refractory anemia with ringed sideroblasts    
11q23 del(11)(q23) Refractory anemia with ringed sideroblasts    
11q24 del(11)(q13q24) Refractory anemia with ringed sideroblasts    
12p11 del(12)(p11) Refractory anemia with ringed sideroblasts    
12p12 del(12)(p12) Refractory anemia with ringed sideroblasts    
12p13 add(12)(p13) Refractory anemia with ringed sideroblasts    
13q12 del(13)(q12q14) Refractory anemia with ringed sideroblasts    
13q13 del(13)(q13q21) Refractory anemia with ringed sideroblasts    
13q14 del(13)(q12q14) Refractory anemia with ringed sideroblasts    
13q21 del(13)(q13q21) Refractory anemia with ringed sideroblasts    
15p11 add(15)(p11) Refractory anemia with ringed sideroblasts    
15p11 der(15)t(1;15)(q12;p11) Refractory anemia with ringed sideroblasts    
17p11 add(17)(p11) Refractory anemia with ringed sideroblasts    
17q10 i(17)(q10) Refractory anemia with ringed sideroblasts    
18q23 add(18)(q23) Refractory anemia with ringed sideroblasts    
19p13 add(19)(p13) Refractory anemia with ringed sideroblasts    
19p13 der(1)t(1;19)(p13;p13) Refractory anemia with ringed sideroblasts    
20q11 del(20)(q11) Refractory anemia with ringed sideroblasts   12   
20q11 del(20)(q11q13) Refractory anemia with ringed sideroblasts   13   
20q12 del(20)(q12) Refractory anemia with ringed sideroblasts    
20q12 del(20)(q12q13) Refractory anemia with ringed sideroblasts    
20q13 del(20)(q11q13) Refractory anemia with ringed sideroblasts   13   
20q13 del(20)(q12q13) Refractory anemia with ringed sideroblasts    
Xq13 idic(X)(q13) Refractory anemia with ringed sideroblasts    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Refractory anemia with ringed sideroblasts    
+6 Refractory anemia with ringed sideroblasts    
+8 Refractory anemia with ringed sideroblasts   58   
+9 Refractory anemia with ringed sideroblasts    
+11 Refractory anemia with ringed sideroblasts    
+14 Refractory anemia with ringed sideroblasts    
+15 Refractory anemia with ringed sideroblasts    
+16 Refractory anemia with ringed sideroblasts    
+18 Refractory anemia with ringed sideroblasts    
+19 Refractory anemia with ringed sideroblasts    
+21 Refractory anemia with ringed sideroblasts   12   
+X Refractory anemia with ringed sideroblasts    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-3 Refractory anemia with ringed sideroblasts    
-4 Refractory anemia with ringed sideroblasts    
-5 Refractory anemia with ringed sideroblasts   13   
-7 Refractory anemia with ringed sideroblasts   30   
-8 Refractory anemia with ringed sideroblasts    
-9 Refractory anemia with ringed sideroblasts    
-10 Refractory anemia with ringed sideroblasts    
-12 Refractory anemia with ringed sideroblasts    
-13 Refractory anemia with ringed sideroblasts    
-14 Refractory anemia with ringed sideroblasts    
-15 Refractory anemia with ringed sideroblasts    
-16 Refractory anemia with ringed sideroblasts    
-17 Refractory anemia with ringed sideroblasts   13   
-18 Refractory anemia with ringed sideroblasts    
-19 Refractory anemia with ringed sideroblasts    
-20 Refractory anemia with ringed sideroblasts    
-21 Refractory anemia with ringed sideroblasts    
-22 Refractory anemia with ringed sideroblasts    
-X Refractory anemia with ringed sideroblasts    
-Y Refractory anemia with ringed sideroblasts   19