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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p11 t(1;7)(p11;p11) Refractory anemia    
2p21 t(2;11)(p21;q23) Refractory anemia    
3q21 inv(3)(q21q26) Refractory anemia    
3q21 t(3;12)(q21;p13) Refractory anemia    
3q26 inv(3)(q21q26) Refractory anemia    
7p11 t(1;7)(p11;p11) Refractory anemia    
9p22 t(9;11)(p22;q23) Refractory anemia    
9q34 t(9;22)(q34;q11) Refractory anemia   BCR/ABL1
11q23 t(2;11)(p21;q23) Refractory anemia    
11q23 t(9;11)(p22;q23) Refractory anemia    
12p13 t(3;12)(q21;p13) Refractory anemia    
12q15 inv(12)(q15q24) Refractory anemia    
12q24 inv(12)(q15q24) Refractory anemia    
18p11 t(18;22)(p11;q11) Refractory anemia    
22q11 t(18;22)(p11;q11) Refractory anemia    
22q11 t(9;22)(q34;q11) Refractory anemia   BCR/ABL1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p11 der(1)t(1;7)(p11;p11) Refractory anemia   15   
1p11 dic(1;7)(p11;q11) Refractory anemia    
1p13 del(1)(p13) Refractory anemia    
1q10 der(1;7)(q10;p10) Refractory anemia   89   
1q11 der(15)t(1;15)(q11;p11) Refractory anemia    
1q21 dup(1)(q21q42) Refractory anemia    
1q42 dup(1)(q21q42) Refractory anemia    
2q32 add(2)(q32) Refractory anemia    
4p16 add(4)(p16) Refractory anemia    
5p10 der(5;17)(p10;q10) Refractory anemia    
5q11 idic(5)(q11) Refractory anemia    
5q12 del(5)(q12) Refractory anemia    
5q12 del(5)(q12q31) Refractory anemia    
5q12 del(5)(q12q32) Refractory anemia    
5q12 del(5)(q12q33) Refractory anemia    
5q12 del(5)(q12q34) Refractory anemia    
5q13 del(5)(q13) Refractory anemia    
5q13 del(5)(q13q22) Refractory anemia    
5q13 del(5)(q13q23) Refractory anemia    
5q13 del(5)(q13q31) Refractory anemia   14   
5q13 del(5)(q13q33) Refractory anemia   125   
5q13 del(5)(q13q34) Refractory anemia    
5q13 del(5)(q13q35) Refractory anemia    
5q14 del(5)(q14) Refractory anemia    
5q14 del(5)(q14q32) Refractory anemia    
5q14 del(5)(q14q33) Refractory anemia   16   
5q14 del(5)(q14q34) Refractory anemia   27   
5q15 del(5)(q15q31) Refractory anemia    
5q15 del(5)(q15q33) Refractory anemia   15   
5q21 del(5)(q21) Refractory anemia    
5q21 del(5)(q21q33) Refractory anemia    
5q21 del(5)(q21q35) Refractory anemia    
5q22 del(5)(q13q22) Refractory anemia    
5q22 del(5)(q22q33) Refractory anemia   26   
5q22 del(5)(q22q35) Refractory anemia    
5q23 del(5)(q13q23) Refractory anemia    
5q23 del(5)(q23q32) Refractory anemia    
5q23 del(5)(q23q33) Refractory anemia    
5q23 del(5)(q23q34) Refractory anemia    
5q31 del(5)(q12q31) Refractory anemia    
5q31 del(5)(q13q31) Refractory anemia   14   
5q31 del(5)(q15q31) Refractory anemia    
5q31 del(5)(q31) Refractory anemia    
5q31 del(5)(q31q33) Refractory anemia    
5q31 del(5)(q31q35) Refractory anemia   11   
5q32 del(5)(q12q32) Refractory anemia    
5q32 del(5)(q14q32) Refractory anemia    
5q32 del(5)(q23q32) Refractory anemia    
5q33 del(5)(q12q33) Refractory anemia    
5q33 del(5)(q13q33) Refractory anemia   125   
5q33 del(5)(q14q33) Refractory anemia   16   
5q33 del(5)(q15q33) Refractory anemia   15   
5q33 del(5)(q21q33) Refractory anemia    
5q33 del(5)(q22q33) Refractory anemia   26   
5q33 del(5)(q23q33) Refractory anemia    
5q33 del(5)(q31q33) Refractory anemia    
5q34 del(5)(q12q34) Refractory anemia    
5q34 del(5)(q13q34) Refractory anemia    
5q34 del(5)(q14q34) Refractory anemia   27   
5q34 del(5)(q23q34) Refractory anemia    
5q35 del(5)(q13q35) Refractory anemia    
5q35 del(5)(q21q35) Refractory anemia    
5q35 del(5)(q22q35) Refractory anemia    
5q35 del(5)(q31q35) Refractory anemia   11   
6p10 i(6)(p10) Refractory anemia    
6q15 del(6)(q15q27) Refractory anemia    
6q21 del(6)(q21) Refractory anemia    
6q27 del(6)(q15q27) Refractory anemia    
7p10 der(1;7)(q10;p10) Refractory anemia   89   
7p11 der(1)t(1;7)(p11;p11) Refractory anemia   15   
7q11 del(7)(q11) Refractory anemia    
7q11 dic(1;7)(p11;q11) Refractory anemia    
7q22 del(7)(q22) Refractory anemia   16   
7q22 del(7)(q22q32) Refractory anemia    
7q22 del(7)(q22q34) Refractory anemia    
7q31 del(7)(q31) Refractory anemia    
7q31 del(7)(q31q33) Refractory anemia    
7q31 del(7)(q31q34) Refractory anemia    
7q31 del(7)(q31q36) Refractory anemia    
7q32 del(7)(q22q32) Refractory anemia    
7q32 del(7)(q32) Refractory anemia    
7q33 del(7)(q31q33) Refractory anemia    
7q34 del(7)(q22q34) Refractory anemia    
7q34 del(7)(q31q34) Refractory anemia    
7q36 del(7)(q31q36) Refractory anemia    
9q11 del(9)(q11q22) Refractory anemia    
9q12 del(9)(q12q22) Refractory anemia    
9q22 del(9)(q11q22) Refractory anemia    
9q22 del(9)(q12q22) Refractory anemia    
11q13 del(11)(q13q23) Refractory anemia    
11q14 del(11)(q14) Refractory anemia    
11q14 del(11)(q14q23) Refractory anemia    
11q21 del(11)(q21q23) Refractory anemia    
11q23 del(11)(q13q23) Refractory anemia    
11q23 del(11)(q14q23) Refractory anemia    
11q23 del(11)(q21q23) Refractory anemia    
11q23 del(11)(q23) Refractory anemia    
11q24 der(11)t(11;21)(q24;q11) Refractory anemia    
12p11 del(12)(p11) Refractory anemia    
12p11 del(12)(p11p12) Refractory anemia    

Band Abnormality Morphology Topography Cases Genes
12p12 del(12)(p11p12) Refractory anemia    
12p12 del(12)(p12) Refractory anemia    
12p13 add(12)(p13) Refractory anemia    
12q21 del(12)(q21q23) Refractory anemia    
12q23 del(12)(q21q23) Refractory anemia    
13p11 add(13)(p11) Refractory anemia    
13q12 del(13)(q12q14) Refractory anemia   10   
13q13 del(13)(q13q22) Refractory anemia    
13q14 del(13)(q12q14) Refractory anemia   10   
13q22 del(13)(q13q22) Refractory anemia    
13q32 add(13)(q32) Refractory anemia    
14p11 add(14)(p11) Refractory anemia    
14q10 i(14)(q10) Refractory anemia    
14q32 add(14)(q32) Refractory anemia    
15p11 der(15)t(1;15)(q11;p11) Refractory anemia    
16q22 del(16)(q22) Refractory anemia    
16q24 add(16)(q24) Refractory anemia    
17p11 add(17)(p11) Refractory anemia    
17p11 del(17)(p11) Refractory anemia    
17p11 del(17)(p11p13) Refractory anemia    
17p12 del(17)(p12) Refractory anemia    
17p13 add(17)(p13) Refractory anemia    
17p13 del(17)(p11p13) Refractory anemia    
17q10 der(5;17)(p10;q10) Refractory anemia    
17q10 i(17)(q10) Refractory anemia    
18p11 add(18)(p11) Refractory anemia    
19p13 add(19)(p13) Refractory anemia    
20p11 der(20;20)t(20;20)(p11;p11)del(20)(q11q13)del(20) Refractory anemia    
20p11 der(20;20)t(20;20)(p11;p11)del(20)(q11q13)del(20) Refractory anemia    
20q10 ider(20)(q10)del(20)(q11) Refractory anemia    
20q10 ider(20)(q10)del(20)(q11q13) Refractory anemia    
20q11 del(20)(q11) Refractory anemia   52   
20q11 del(20)(q11q13) Refractory anemia   17   
20q11 der(20;20)t(20;20)(p11;p11)del(20)(q11q13)del(20) Refractory anemia    
20q11 ider(20)(q10)del(20)(q11) Refractory anemia    
20q11 ider(20)(q10)del(20)(q11q13) Refractory anemia    
20q12 del(20)(q12) Refractory anemia   17   
20q12 del(20)(q12q13) Refractory anemia    
20q13 del(20)(q11q13) Refractory anemia   17   
20q13 del(20)(q12q13) Refractory anemia    
20q13 der(20;20)t(20;20)(p11;p11)del(20)(q11q13)del(20) Refractory anemia    
20q13 ider(20)(q10)del(20)(q11q13) Refractory anemia    
21p11 add(21)(p11) Refractory anemia    
21q10 i(21)(q10) Refractory anemia    
21q11 der(11)t(11;21)(q24;q11) Refractory anemia    
21q22 add(21)(q22) Refractory anemia    
22p11 add(22)(p11) Refractory anemia    
22q12 add(22)(q12) Refractory anemia    
Xp10 i(X)(p10) Refractory anemia    
Xq13 idic(X)(q13) Refractory anemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Refractory anemia   97   
+2 Refractory anemia    
+3 Refractory anemia    
+6 Refractory anemia    
+8 Refractory anemia   170   
+9 Refractory anemia    
+10 Refractory anemia    
+11 Refractory anemia    
+13 Refractory anemia    
+14 Refractory anemia    
+15 Refractory anemia   10   
+16 Refractory anemia    
+18 Refractory anemia    
+19 Refractory anemia   12   
+20 Refractory anemia    
+21 Refractory anemia   39   
+22 Refractory anemia    
+X Refractory anemia    
+Y Refractory anemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Refractory anemia    
-2 Refractory anemia    
-3 Refractory anemia    
-4 Refractory anemia    
-5 Refractory anemia   37   
-6 Refractory anemia    
-7 Refractory anemia   118   
-8 Refractory anemia    
-9 Refractory anemia    
-10 Refractory anemia    
-11 Refractory anemia    
-12 Refractory anemia   16   
-13 Refractory anemia   12   
-14 Refractory anemia   11   
-15 Refractory anemia    
-16 Refractory anemia    
-17 Refractory anemia   20   
-18 Refractory anemia   27   
-19 Refractory anemia    
-20 Refractory anemia   25   
-21 Refractory anemia   16   
-22 Refractory anemia   12   
-X Refractory anemia   11   
-Y Refractory anemia   46