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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
3q21 inv(3)(q21q26) Idiopathic myelofibrosis    
3q21 t(3;21)(q21;q22) Idiopathic myelofibrosis    
3q26 inv(3)(q21q26) Idiopathic myelofibrosis    
21q22 t(3;21)(q21;q22) Idiopathic myelofibrosis    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p11 der(1)t(1;7)(p11;p11) Idiopathic myelofibrosis    
1p13 der(1)t(1;19)(p13;p13) Idiopathic myelofibrosis    
1q10 der(1;7)(q10;p10) Idiopathic myelofibrosis    
1q10 der(1;9)(q10;p10) Idiopathic myelofibrosis    
1q21 del(1)(q21) Idiopathic myelofibrosis    
1q21 dup(1)(q21q32) Idiopathic myelofibrosis    
1q21 dup(1)(q21q42) Idiopathic myelofibrosis    
1q32 dup(1)(q21q32) Idiopathic myelofibrosis    
1q42 dup(1)(q21q42) Idiopathic myelofibrosis    
5q13 del(5)(q13q31) Idiopathic myelofibrosis    
5q31 del(5)(q13q31) Idiopathic myelofibrosis    
6p21 del(6)(p21p23) Idiopathic myelofibrosis    
6p23 del(6)(p21p23) Idiopathic myelofibrosis    
7p10 der(1;7)(q10;p10) Idiopathic myelofibrosis    
7p11 der(1)t(1;7)(p11;p11) Idiopathic myelofibrosis    
7p15 del(7)(p15) Idiopathic myelofibrosis    
7q22 del(7)(q22) Idiopathic myelofibrosis    
7q22 del(7)(q22q32) Idiopathic myelofibrosis    
7q32 del(7)(q22q32) Idiopathic myelofibrosis    
9p10 der(1;9)(q10;p10) Idiopathic myelofibrosis    
11q13 del(11)(q13q21) Idiopathic myelofibrosis    
11q14 del(11)(q14) Idiopathic myelofibrosis    
11q21 del(11)(q13q21) Idiopathic myelofibrosis    
12p11 del(12)(p11) Idiopathic myelofibrosis    
12p11 del(12)(p11p13) Idiopathic myelofibrosis    
12p13 del(12)(p11p13) Idiopathic myelofibrosis    
13q12 del(13)(q12q14) Idiopathic myelofibrosis   13   
13q12 del(13)(q12q21) Idiopathic myelofibrosis    
13q12 del(13)(q12q22) Idiopathic myelofibrosis    
13q13 del(13)(q13q21) Idiopathic myelofibrosis    
13q13 del(13)(q13q31) Idiopathic myelofibrosis    
13q13 del(13)(q13q32) Idiopathic myelofibrosis    
13q14 del(13)(q12q14) Idiopathic myelofibrosis   13   
13q14 del(13)(q14q21) Idiopathic myelofibrosis    
13q21 del(13)(q12q21) Idiopathic myelofibrosis    
13q21 del(13)(q13q21) Idiopathic myelofibrosis    
13q21 del(13)(q14q21) Idiopathic myelofibrosis    
13q22 del(13)(q12q22) Idiopathic myelofibrosis    
13q31 del(13)(q13q31) Idiopathic myelofibrosis    
13q32 del(13)(q13q32) Idiopathic myelofibrosis    
17q10 i(17)(q10) Idiopathic myelofibrosis    
18p11 add(18)(p11) Idiopathic myelofibrosis    
19p13 der(1)t(1;19)(p13;p13) Idiopathic myelofibrosis    
20q11 del(20)(q11) Idiopathic myelofibrosis   33   
20q11 del(20)(q11q13) Idiopathic myelofibrosis    
20q12 del(20)(q12) Idiopathic myelofibrosis    
20q13 del(20)(q11q13) Idiopathic myelofibrosis    
21q22 add(21)(q22) Idiopathic myelofibrosis    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Idiopathic myelofibrosis   11   
+2 Idiopathic myelofibrosis    
+5 Idiopathic myelofibrosis    
+6 Idiopathic myelofibrosis    
+8 Idiopathic myelofibrosis   44   
+9 Idiopathic myelofibrosis   19   
+10 Idiopathic myelofibrosis    
+11 Idiopathic myelofibrosis    
+12 Idiopathic myelofibrosis    
+13 Idiopathic myelofibrosis    
+17 Idiopathic myelofibrosis    
+19 Idiopathic myelofibrosis    
+20 Idiopathic myelofibrosis    
+21 Idiopathic myelofibrosis   15   
+Y Idiopathic myelofibrosis    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-3 Idiopathic myelofibrosis    
-5 Idiopathic myelofibrosis    
-6 Idiopathic myelofibrosis    
-7 Idiopathic myelofibrosis   19   
-8 Idiopathic myelofibrosis    
-9 Idiopathic myelofibrosis    
-10 Idiopathic myelofibrosis    
-11 Idiopathic myelofibrosis    
-12 Idiopathic myelofibrosis    
-13 Idiopathic myelofibrosis    
-14 Idiopathic myelofibrosis    
-15 Idiopathic myelofibrosis    
-17 Idiopathic myelofibrosis    
-19 Idiopathic myelofibrosis    
-20 Idiopathic myelofibrosis    
-Y Idiopathic myelofibrosis