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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p36 t(1;3)(p36;q21) Chronic myelomonocytic leukemia   RPN1/PRDM16
3q21 inv(3)(q21q26) Chronic myelomonocytic leukemia    
3q21 t(1;3)(p36;q21) Chronic myelomonocytic leukemia   RPN1/PRDM16
3q26 inv(3)(q21q26) Chronic myelomonocytic leukemia    
3q26 t(3;21)(q26;q22) Chronic myelomonocytic leukemia    
5q33 t(5;12)(q33;p13) Chronic myelomonocytic leukemia   11   
7p15 t(7;11)(p15;p15) Chronic myelomonocytic leukemia   NUP98/HOXA9
9p11 inv(9)(p11q13) Chronic myelomonocytic leukemia    
9p22 t(9;11)(p22;q23) Chronic myelomonocytic leukemia   KMT2A+
9q13 inv(9)(p11q13) Chronic myelomonocytic leukemia    
9q34 t(9;22)(q34;q11) Chronic myelomonocytic leukemia    
11p15 t(7;11)(p15;p15) Chronic myelomonocytic leukemia   NUP98/HOXA9
11q23 t(11;16)(q23;p13) Chronic myelomonocytic leukemia   KMT2A/CREBBP
11q23 t(11;19)(q23;p13) Chronic myelomonocytic leukemia   KMT2A/ELL,KMT2A+
11q23 t(9;11)(p22;q23) Chronic myelomonocytic leukemia   KMT2A+
12p13 t(5;12)(q33;p13) Chronic myelomonocytic leukemia   11   
16p13 t(11;16)(q23;p13) Chronic myelomonocytic leukemia   KMT2A/CREBBP
19p13 t(11;19)(q23;p13) Chronic myelomonocytic leukemia   KMT2A/ELL,KMT2A+
21q22 t(3;21)(q26;q22) Chronic myelomonocytic leukemia    
22q11 t(9;22)(q34;q11) Chronic myelomonocytic leukemia    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p11 der(1)t(1;7)(p11;p11) Chronic myelomonocytic leukemia    
1q10 der(1;7)(q10;p10) Chronic myelomonocytic leukemia    
4q21 del(4)(q21q26) Chronic myelomonocytic leukemia    
4q26 del(4)(q21q26) Chronic myelomonocytic leukemia    
5q13 del(5)(q13q33) Chronic myelomonocytic leukemia    
5q13 del(5)(q13q35) Chronic myelomonocytic leukemia    
5q15 del(5)(q15q33) Chronic myelomonocytic leukemia    
5q31 del(5)(q31) Chronic myelomonocytic leukemia    
5q33 del(5)(q13q33) Chronic myelomonocytic leukemia    
5q33 del(5)(q15q33) Chronic myelomonocytic leukemia    
5q35 del(5)(q13q35) Chronic myelomonocytic leukemia    
7p10 der(1;7)(q10;p10) Chronic myelomonocytic leukemia    
7p11 der(1)t(1;7)(p11;p11) Chronic myelomonocytic leukemia    
7q21 del(7)(q21q31) Chronic myelomonocytic leukemia    
7q22 del(7)(q22) Chronic myelomonocytic leukemia    
7q22 del(7)(q22q34) Chronic myelomonocytic leukemia    
7q22 del(7)(q22q36) Chronic myelomonocytic leukemia    
7q31 del(7)(q21q31) Chronic myelomonocytic leukemia    
7q34 del(7)(q22q34) Chronic myelomonocytic leukemia    
7q36 del(7)(q22q36) Chronic myelomonocytic leukemia    
8q10 i(8)(q10) Chronic myelomonocytic leukemia    
11q23 del(11)(q23) Chronic myelomonocytic leukemia    
12p11 del(12)(p11) Chronic myelomonocytic leukemia    
12p11 del(12)(p11p13) Chronic myelomonocytic leukemia    
12p12 del(12)(p12) Chronic myelomonocytic leukemia    
12p13 del(12)(p11p13) Chronic myelomonocytic leukemia    
13q12 del(13)(q12q22) Chronic myelomonocytic leukemia    
13q22 del(13)(q12q22) Chronic myelomonocytic leukemia    
14q10 i(14)(q10) Chronic myelomonocytic leukemia    
17p11 del(17)(p11) Chronic myelomonocytic leukemia    
17q10 i(17)(q10) Chronic myelomonocytic leukemia   13   
18q21 add(18)(q21) Chronic myelomonocytic leukemia    
20q11 del(20)(q11) Chronic myelomonocytic leukemia    
20q11 del(20)(q11q13) Chronic myelomonocytic leukemia   10   
20q12 del(20)(q12) Chronic myelomonocytic leukemia    
20q13 del(20)(q11q13) Chronic myelomonocytic leukemia   10   
21q21 del(21)(q21q22) Chronic myelomonocytic leukemia   USP16/RUNX1
21q22 add(21)(q22) Chronic myelomonocytic leukemia    
21q22 del(21)(q21q22) Chronic myelomonocytic leukemia   USP16/RUNX1
Xp10 i(X)(p10) Chronic myelomonocytic leukemia    
Xq13 idic(X)(q13) Chronic myelomonocytic leukemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Chronic myelomonocytic leukemia   11   
+2 Chronic myelomonocytic leukemia    
+4 Chronic myelomonocytic leukemia    
+5 Chronic myelomonocytic leukemia    
+6 Chronic myelomonocytic leukemia    
+7 Chronic myelomonocytic leukemia    
+8 Chronic myelomonocytic leukemia   92   
+9 Chronic myelomonocytic leukemia    
+10 Chronic myelomonocytic leukemia    
+11 Chronic myelomonocytic leukemia    
+12 Chronic myelomonocytic leukemia    
+13 Chronic myelomonocytic leukemia    
+14 Chronic myelomonocytic leukemia    
+19 Chronic myelomonocytic leukemia   11   
+20 Chronic myelomonocytic leukemia    
+21 Chronic myelomonocytic leukemia   24   
+22 Chronic myelomonocytic leukemia    
+Y Chronic myelomonocytic leukemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Chronic myelomonocytic leukemia    
-3 Chronic myelomonocytic leukemia    
-4 Chronic myelomonocytic leukemia    
-5 Chronic myelomonocytic leukemia    
-6 Chronic myelomonocytic leukemia    
-7 Chronic myelomonocytic leukemia   52   
-8 Chronic myelomonocytic leukemia    
-10 Chronic myelomonocytic leukemia    
-12 Chronic myelomonocytic leukemia    
-13 Chronic myelomonocytic leukemia    
-15 Chronic myelomonocytic leukemia    
-16 Chronic myelomonocytic leukemia    
-17 Chronic myelomonocytic leukemia   11   
-18 Chronic myelomonocytic leukemia    
-19 Chronic myelomonocytic leukemia    
-20 Chronic myelomonocytic leukemia    
-21 Chronic myelomonocytic leukemia    
-22 Chronic myelomonocytic leukemia    
-X Chronic myelomonocytic leukemia    
-Y Chronic myelomonocytic leukemia   32