Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Chromosomes
  • Tools
  • Genetic and Physical SNP Maps
  • SNP500Cancer
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p13 t(1;22)(p13;q13) Acute megakaryoblastic leukemia (FAB type M7)   47  RBM15/MKL1
2p12 t(2;7)(p12;p22) Acute megakaryoblastic leukemia (FAB type M7)    
3q21 inv(3)(q21q26) Acute megakaryoblastic leukemia (FAB type M7)   23  MECOM+
3q21 t(3;22;5)(q21;q13;q31) Acute megakaryoblastic leukemia (FAB type M7)    
3q21 t(3;3)(q21;q26) Acute megakaryoblastic leukemia (FAB type M7)   11   
3q26 inv(3)(q21q26) Acute megakaryoblastic leukemia (FAB type M7)   23  MECOM+
3q26 t(3;3)(q21;q26) Acute megakaryoblastic leukemia (FAB type M7)   11   
4q21 t(4;11)(q21;q23) Acute megakaryoblastic leukemia (FAB type M7)   KMT2A/AFF1
5q31 t(3;22;5)(q21;q13;q31) Acute megakaryoblastic leukemia (FAB type M7)    
7p22 t(2;7)(p12;p22) Acute megakaryoblastic leukemia (FAB type M7)    
9p21 t(9;11)(p21;q23) Acute megakaryoblastic leukemia (FAB type M7)   KMT2A/MLLT3,KMT2A+
9p22 t(9;11)(p22;q23) Acute megakaryoblastic leukemia (FAB type M7)    
9q34 t(9;22)(q34;q11) Acute megakaryoblastic leukemia (FAB type M7)   19  BCR/ABL1
11p15 t(11;17)(p15;q23) Acute megakaryoblastic leukemia (FAB type M7)   NUP98+
11q23 t(4;11)(q21;q23) Acute megakaryoblastic leukemia (FAB type M7)   KMT2A/AFF1
11q23 t(9;11)(p21;q23) Acute megakaryoblastic leukemia (FAB type M7)   KMT2A/MLLT3,KMT2A+
11q23 t(9;11)(p22;q23) Acute megakaryoblastic leukemia (FAB type M7)    
16p11 t(16;21)(p11;q22) Acute megakaryoblastic leukemia (FAB type M7)   FUS/ERG
16p13 inv(16)(p13q22) Acute megakaryoblastic leukemia (FAB type M7)    
16p13 inv(16)(p13q24) Acute megakaryoblastic leukemia (FAB type M7)   CBFA2T3/GLIS2
16q22 inv(16)(p13q22) Acute megakaryoblastic leukemia (FAB type M7)    
16q24 inv(16)(p13q24) Acute megakaryoblastic leukemia (FAB type M7)   CBFA2T3/GLIS2
17q23 t(11;17)(p15;q23) Acute megakaryoblastic leukemia (FAB type M7)   NUP98+
21q22 t(16;21)(p11;q22) Acute megakaryoblastic leukemia (FAB type M7)   FUS/ERG
22q11 t(9;22)(q34;q11) Acute megakaryoblastic leukemia (FAB type M7)   19  BCR/ABL1
22q13 t(1;22)(p13;q13) Acute megakaryoblastic leukemia (FAB type M7)   47  RBM15/MKL1
22q13 t(3;22;5)(q21;q13;q31) Acute megakaryoblastic leukemia (FAB type M7)    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p13 add(1)(p13) Acute megakaryoblastic leukemia (FAB type M7)    
1p13 der(1)t(1;22)(p13;q13) Acute megakaryoblastic leukemia (FAB type M7)   10   
1p36 add(1)(p36) Acute megakaryoblastic leukemia (FAB type M7)    
1q10 der(1;7)(q10;p10) Acute megakaryoblastic leukemia (FAB type M7)    
1q10 i(1)(q10) Acute megakaryoblastic leukemia (FAB type M7)    
1q11 add(1)(q11) Acute megakaryoblastic leukemia (FAB type M7)    
1q21 der(16)t(1;16)(q21;p13) Acute megakaryoblastic leukemia (FAB type M7)    
1q23 der(2)t(1;2)(q23;q35) Acute megakaryoblastic leukemia (FAB type M7)    
1q25 der(X)t(X;1)(q28;q25) Acute megakaryoblastic leukemia (FAB type M7)    
1q32 dup(1)(q32q44) Acute megakaryoblastic leukemia (FAB type M7)    
1q44 dup(1)(q32q44) Acute megakaryoblastic leukemia (FAB type M7)    
2p11 add(2)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
2q11 del(2)(q11) Acute megakaryoblastic leukemia (FAB type M7)    
2q11 der(5)t(2;5)(q11;q22) Acute megakaryoblastic leukemia (FAB type M7)    
2q31 del(2)(q31) Acute megakaryoblastic leukemia (FAB type M7)    
2q35 der(2)t(1;2)(q23;q35) Acute megakaryoblastic leukemia (FAB type M7)    
3p11 add(3)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
3p12 del(3)(p12) Acute megakaryoblastic leukemia (FAB type M7)    
3q21 add(3)(q21) Acute megakaryoblastic leukemia (FAB type M7)    
3q21 der(11)t(3;11)(q21;p15) Acute megakaryoblastic leukemia (FAB type M7)    
3q21 dup(3)(q21q29) Acute megakaryoblastic leukemia (FAB type M7)    
3q26 add(3)(q26) Acute megakaryoblastic leukemia (FAB type M7)    
3q29 dup(3)(q21q29) Acute megakaryoblastic leukemia (FAB type M7)    
4q21 add(4)(q21) Acute megakaryoblastic leukemia (FAB type M7)    
4q31 add(4)(q31) Acute megakaryoblastic leukemia (FAB type M7)    
5p10 der(5;17)(p10;q10) Acute megakaryoblastic leukemia (FAB type M7)    
5p11 add(5)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
5p13 del(5)(p13) Acute megakaryoblastic leukemia (FAB type M7)    
5p13 del(5)(p13p14) Acute megakaryoblastic leukemia (FAB type M7)    
5p14 del(5)(p13p14) Acute megakaryoblastic leukemia (FAB type M7)    
5p15 add(5)(p15) Acute megakaryoblastic leukemia (FAB type M7)    
5q11 der(5)t(5;9)(q11;q13) Acute megakaryoblastic leukemia (FAB type M7)    
5q12 del(5)(q12) Acute megakaryoblastic leukemia (FAB type M7)    
5q13 del(5)(q13) Acute megakaryoblastic leukemia (FAB type M7)    
5q13 del(5)(q13q22) Acute megakaryoblastic leukemia (FAB type M7)    
5q13 del(5)(q13q31) Acute megakaryoblastic leukemia (FAB type M7)    
5q13 del(5)(q13q33) Acute megakaryoblastic leukemia (FAB type M7)    
5q13 dic(5;7)(q13;p22) Acute megakaryoblastic leukemia (FAB type M7)    
5q21 del(5)(q21q34) Acute megakaryoblastic leukemia (FAB type M7)    
5q22 del(5)(q13q22) Acute megakaryoblastic leukemia (FAB type M7)    
5q22 del(5)(q22q33) Acute megakaryoblastic leukemia (FAB type M7)    
5q22 der(5)t(2;5)(q11;q22) Acute megakaryoblastic leukemia (FAB type M7)    
5q31 del(5)(q13q31) Acute megakaryoblastic leukemia (FAB type M7)    
5q31 del(5)(q31q35) Acute megakaryoblastic leukemia (FAB type M7)    
5q33 del(5)(q13q33) Acute megakaryoblastic leukemia (FAB type M7)    
5q33 del(5)(q22q33) Acute megakaryoblastic leukemia (FAB type M7)    
5q34 del(5)(q21q34) Acute megakaryoblastic leukemia (FAB type M7)    
5q35 del(5)(q31q35) Acute megakaryoblastic leukemia (FAB type M7)    
6p25 add(6)(p25) Acute megakaryoblastic leukemia (FAB type M7)    
6q21 del(6)(q21q24) Acute megakaryoblastic leukemia (FAB type M7)    
6q21 del(6)(q21q25) Acute megakaryoblastic leukemia (FAB type M7)    
6q23 add(6)(q23) Acute megakaryoblastic leukemia (FAB type M7)    
6q24 del(6)(q21q24) Acute megakaryoblastic leukemia (FAB type M7)    
6q25 del(6)(q21q25) Acute megakaryoblastic leukemia (FAB type M7)    
7p10 add(7)(p10) Acute megakaryoblastic leukemia (FAB type M7)    
7p10 der(1;7)(q10;p10) Acute megakaryoblastic leukemia (FAB type M7)    
7p11 add(7)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
7p13 del(7)(p13) Acute megakaryoblastic leukemia (FAB type M7)    
7p15 del(7)(p15) Acute megakaryoblastic leukemia (FAB type M7)    
7p22 add(7)(p22) Acute megakaryoblastic leukemia (FAB type M7)    
7p22 dic(5;7)(q13;p22) Acute megakaryoblastic leukemia (FAB type M7)    
7p22 r(7)(p22q11) Acute megakaryoblastic leukemia (FAB type M7)    
7q10 i(7)(q10) Acute megakaryoblastic leukemia (FAB type M7)   16   
7q11 r(7)(p22q11) Acute megakaryoblastic leukemia (FAB type M7)    
7q22 add(7)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
7q22 del(7)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
7q22 del(7)(q22q36) Acute megakaryoblastic leukemia (FAB type M7)    
7q31 del(7)(q31) Acute megakaryoblastic leukemia (FAB type M7)    
7q32 del(7)(q32) Acute megakaryoblastic leukemia (FAB type M7)    
7q36 del(7)(q22q36) Acute megakaryoblastic leukemia (FAB type M7)    
8q10 i(8)(q10) Acute megakaryoblastic leukemia (FAB type M7)    
8q22 add(8)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
8q24 add(8)(q24) Acute megakaryoblastic leukemia (FAB type M7)    
9p11 add(9)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
9p13 add(9)(p13) Acute megakaryoblastic leukemia (FAB type M7)    
9p21 del(9)(p21) Acute megakaryoblastic leukemia (FAB type M7)    
9p22 del(9)(p22) Acute megakaryoblastic leukemia (FAB type M7)    
9p24 add(9)(p24) Acute megakaryoblastic leukemia (FAB type M7)    
9q13 der(5)t(5;9)(q11;q13) Acute megakaryoblastic leukemia (FAB type M7)    
9q22 del(9)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
9q34 add(9)(q34) Acute megakaryoblastic leukemia (FAB type M7)    
9q34 del(9)(q34) Acute megakaryoblastic leukemia (FAB type M7)    
10p13 del(10)(p13) Acute megakaryoblastic leukemia (FAB type M7)    
10q11 der(19)t(10;19)(q11;p13) Acute megakaryoblastic leukemia (FAB type M7)    
10q22 add(10)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
10q26 add(10)(q26) Acute megakaryoblastic leukemia (FAB type M7)    
11p11 add(11)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
11p11 del(11)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
11p15 add(11)(p15) Acute megakaryoblastic leukemia (FAB type M7)    
11p15 der(11)t(3;11)(q21;p15) Acute megakaryoblastic leukemia (FAB type M7)    
11q13 add(11)(q13) Acute megakaryoblastic leukemia (FAB type M7)    
11q13 del(11)(q13) Acute megakaryoblastic leukemia (FAB type M7)    
11q13 del(11)(q13q23) Acute megakaryoblastic leukemia (FAB type M7)    
11q21 add(11)(q21) Acute megakaryoblastic leukemia (FAB type M7)    
11q21 del(11)(q21) Acute megakaryoblastic leukemia (FAB type M7)    
11q22 add(11)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
11q23 add(11)(q23) Acute megakaryoblastic leukemia (FAB type M7)    
11q23 del(11)(q13q23) Acute megakaryoblastic leukemia (FAB type M7)    
11q23 del(11)(q23) Acute megakaryoblastic leukemia (FAB type M7)    
12p10 i(12)(p10) Acute megakaryoblastic leukemia (FAB type M7)    

Band Abnormality Morphology Topography Cases Genes
12p11 add(12)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
12p11 del(12)(p11p12) Acute megakaryoblastic leukemia (FAB type M7)    
12p12 del(12)(p11p12) Acute megakaryoblastic leukemia (FAB type M7)    
12p12 del(12)(p12) Acute megakaryoblastic leukemia (FAB type M7)    
12q24 add(12)(q24) Acute megakaryoblastic leukemia (FAB type M7)    
13q12 del(13)(q12q14) Acute megakaryoblastic leukemia (FAB type M7)   10   
13q12 del(13)(q12q22) Acute megakaryoblastic leukemia (FAB type M7)    
13q13 del(13)(q13q31) Acute megakaryoblastic leukemia (FAB type M7)    
13q13 del(13)(q13q32) Acute megakaryoblastic leukemia (FAB type M7)    
13q14 del(13)(q12q14) Acute megakaryoblastic leukemia (FAB type M7)   10   
13q14 del(13)(q14q32) Acute megakaryoblastic leukemia (FAB type M7)    
13q22 del(13)(q12q22) Acute megakaryoblastic leukemia (FAB type M7)    
13q31 del(13)(q13q31) Acute megakaryoblastic leukemia (FAB type M7)    
13q32 del(13)(q13q32) Acute megakaryoblastic leukemia (FAB type M7)    
13q32 del(13)(q14q32) Acute megakaryoblastic leukemia (FAB type M7)    
14p11 add(14)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
15p11 add(15)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
15q10 der(15;19)(q10;q10) Acute megakaryoblastic leukemia (FAB type M7)    
16p13 add(16)(p13) Acute megakaryoblastic leukemia (FAB type M7)    
16p13 der(16)t(1;16)(q21;p13) Acute megakaryoblastic leukemia (FAB type M7)    
16q24 add(16)(q24) Acute megakaryoblastic leukemia (FAB type M7)    
17p11 add(17)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
17p11 del(17)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
17q10 der(5;17)(p10;q10) Acute megakaryoblastic leukemia (FAB type M7)    
17q10 i(17)(q10) Acute megakaryoblastic leukemia (FAB type M7)    
17q22 del(17)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
17q25 add(17)(q25) Acute megakaryoblastic leukemia (FAB type M7)    
18p11 add(18)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
18q23 add(18)(q23) Acute megakaryoblastic leukemia (FAB type M7)    
19p13 add(19)(p13) Acute megakaryoblastic leukemia (FAB type M7)   11   
19p13 der(19)t(10;19)(q11;p13) Acute megakaryoblastic leukemia (FAB type M7)    
19q10 der(15;19)(q10;q10) Acute megakaryoblastic leukemia (FAB type M7)    
19q13 add(19)(q13) Acute megakaryoblastic leukemia (FAB type M7)    
20q11 del(20)(q11) Acute megakaryoblastic leukemia (FAB type M7)    
20q11 del(20)(q11q13) Acute megakaryoblastic leukemia (FAB type M7)    
20q12 del(20)(q12) Acute megakaryoblastic leukemia (FAB type M7)    
20q13 del(20)(q11q13) Acute megakaryoblastic leukemia (FAB type M7)    
21p11 add(21)(p11) Acute megakaryoblastic leukemia (FAB type M7)    
21q10 i(21)(q10) Acute megakaryoblastic leukemia (FAB type M7)    
21q22 add(21)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
22q11 add(22)(q11) Acute megakaryoblastic leukemia (FAB type M7)    
22q13 add(22)(q13) Acute megakaryoblastic leukemia (FAB type M7)    
22q13 der(1)t(1;22)(p13;q13) Acute megakaryoblastic leukemia (FAB type M7)   10   
Xq28 der(X)t(X;1)(q28;q25) Acute megakaryoblastic leukemia (FAB type M7)    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Acute megakaryoblastic leukemia (FAB type M7)   12   
+2 Acute megakaryoblastic leukemia (FAB type M7)   19   
+3 Acute megakaryoblastic leukemia (FAB type M7)   14   
+4 Acute megakaryoblastic leukemia (FAB type M7)    
+5 Acute megakaryoblastic leukemia (FAB type M7)    
+6 Acute megakaryoblastic leukemia (FAB type M7)   55   
+7 Acute megakaryoblastic leukemia (FAB type M7)   17   
+8 Acute megakaryoblastic leukemia (FAB type M7)   119   
+9 Acute megakaryoblastic leukemia (FAB type M7)    
+10 Acute megakaryoblastic leukemia (FAB type M7)   20   
+11 Acute megakaryoblastic leukemia (FAB type M7)   23   
+12 Acute megakaryoblastic leukemia (FAB type M7)   10   
+13 Acute megakaryoblastic leukemia (FAB type M7)   15   
+14 Acute megakaryoblastic leukemia (FAB type M7)   19   
+15 Acute megakaryoblastic leukemia (FAB type M7)   13   
+16 Acute megakaryoblastic leukemia (FAB type M7)    
+17 Acute megakaryoblastic leukemia (FAB type M7)    
+18 Acute megakaryoblastic leukemia (FAB type M7)   16   
+19 Acute megakaryoblastic leukemia (FAB type M7)   81   
+20 Acute megakaryoblastic leukemia (FAB type M7)   25   
+21 Acute megakaryoblastic leukemia (FAB type M7)   155   
+22 Acute megakaryoblastic leukemia (FAB type M7)   36   
+X Acute megakaryoblastic leukemia (FAB type M7)   12   
+Y Acute megakaryoblastic leukemia (FAB type M7)    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Acute megakaryoblastic leukemia (FAB type M7)    
-2 Acute megakaryoblastic leukemia (FAB type M7)   10   
-3 Acute megakaryoblastic leukemia (FAB type M7)   25   
-4 Acute megakaryoblastic leukemia (FAB type M7)   21   
-5 Acute megakaryoblastic leukemia (FAB type M7)   40   
-6 Acute megakaryoblastic leukemia (FAB type M7)    
-7 Acute megakaryoblastic leukemia (FAB type M7)   92   
-8 Acute megakaryoblastic leukemia (FAB type M7)    
-9 Acute megakaryoblastic leukemia (FAB type M7)   35   
-10 Acute megakaryoblastic leukemia (FAB type M7)   14   
-11 Acute megakaryoblastic leukemia (FAB type M7)   28   
-12 Acute megakaryoblastic leukemia (FAB type M7)   25   
-13 Acute megakaryoblastic leukemia (FAB type M7)   30   
-14 Acute megakaryoblastic leukemia (FAB type M7)   20   
-15 Acute megakaryoblastic leukemia (FAB type M7)   25   
-16 Acute megakaryoblastic leukemia (FAB type M7)   32   
-17 Acute megakaryoblastic leukemia (FAB type M7)   31   
-18 Acute megakaryoblastic leukemia (FAB type M7)   30   
-19 Acute megakaryoblastic leukemia (FAB type M7)   13   
-20 Acute megakaryoblastic leukemia (FAB type M7)   19   
-21 Acute megakaryoblastic leukemia (FAB type M7)   28   
-22 Acute megakaryoblastic leukemia (FAB type M7)   25   
-X Acute megakaryoblastic leukemia (FAB type M7)   20   
-Y Acute megakaryoblastic leukemia (FAB type M7)