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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p36 t(1;17)(p36;q21) Acute promyelocytic leukemia (FAB type M3)    
1p36 t(1;3)(p36;q21) Acute promyelocytic leukemia (FAB type M3)    
3p25 t(3;17)(p25;q21) Acute promyelocytic leukemia (FAB type M3)   RARA+
3q21 t(1;3)(p36;q21) Acute promyelocytic leukemia (FAB type M3)    
3q26 t(3;17)(q26;q21) Acute promyelocytic leukemia (FAB type M3)   FNDC3B/RARA,TBL1XR1/RARA
4q12 t(4;17)(q12;q21) Acute promyelocytic leukemia (FAB type M3)   FIP1L1/RARA
4q31 t(4;9)(q31;q34) Acute promyelocytic leukemia (FAB type M3)    
5q35 t(5;17)(q35;q21) Acute promyelocytic leukemia (FAB type M3)   NPM1/RARA
8q22 t(8;21)(q22;q22) Acute promyelocytic leukemia (FAB type M3)   RUNX1/RUNX1T1
9q34 t(4;9)(q31;q34) Acute promyelocytic leukemia (FAB type M3)    
9q34 t(9;22)(q34;q11) Acute promyelocytic leukemia (FAB type M3)   BCR/ABL1
11q13 t(11;15;17)(q13;q22;q12) Acute promyelocytic leukemia (FAB type M3)    
11q23 t(11;17)(q23;q21) Acute promyelocytic leukemia (FAB type M3)   12  ZBTB16/RARA
15q12 t(15;17)(q12;q21) Acute promyelocytic leukemia (FAB type M3)    
15q21 t(15;17)(q21;q12) Acute promyelocytic leukemia (FAB type M3)    
15q22 ins(15;17)(q22;q21q21) Acute promyelocytic leukemia (FAB type M3)   PML/CDC6/RARA,PML/RARA,PML/ADAMTS17/RARA
15q22 ins(17;15)(q12;q22q22) Acute promyelocytic leukemia (FAB type M3)    
15q22 ins(17;15)(q12;q22q22) Acute promyelocytic leukemia (FAB type M3)    
15q22 t(11;15;17)(q13;q22;q12) Acute promyelocytic leukemia (FAB type M3)    
15q22 t(15;17)(q22;q11) Acute promyelocytic leukemia (FAB type M3)   109   
15q22 t(15;17)(q22;q12) Acute promyelocytic leukemia (FAB type M3)   266   
15q22 t(15;17)(q22;q21) Acute promyelocytic leukemia (FAB type M3)   624  PML/RARA,RARA+
15q22 t(15;17)(q22;q22) Acute promyelocytic leukemia (FAB type M3)    
15q24 t(15;17)(q24;q21) Acute promyelocytic leukemia (FAB type M3)   60   
15q25 t(15;17)(q25;q22) Acute promyelocytic leukemia (FAB type M3)    
15q26 t(15;17)(q26;q22) Acute promyelocytic leukemia (FAB type M3)   12   
16p13 inv(16)(p13q22) Acute promyelocytic leukemia (FAB type M3)    
16q22 inv(16)(p13q22) Acute promyelocytic leukemia (FAB type M3)    
17q11 t(15;17)(q22;q11) Acute promyelocytic leukemia (FAB type M3)   109   
17q12 ins(17;15)(q12;q22q22) Acute promyelocytic leukemia (FAB type M3)    
17q12 t(11;15;17)(q13;q22;q12) Acute promyelocytic leukemia (FAB type M3)    
17q12 t(15;17)(q21;q12) Acute promyelocytic leukemia (FAB type M3)    
17q12 t(15;17)(q22;q12) Acute promyelocytic leukemia (FAB type M3)   266   
17q21 ins(15;17)(q22;q21q21) Acute promyelocytic leukemia (FAB type M3)   PML/CDC6/RARA,PML/RARA,PML/ADAMTS17/RARA
17q21 ins(15;17)(q22;q21q21) Acute promyelocytic leukemia (FAB type M3)   PML/CDC6/RARA,PML/RARA,PML/ADAMTS17/RARA
17q21 t(11;17)(q23;q21) Acute promyelocytic leukemia (FAB type M3)   12  ZBTB16/RARA
17q21 t(15;17)(q12;q21) Acute promyelocytic leukemia (FAB type M3)    
17q21 t(15;17)(q22;q21) Acute promyelocytic leukemia (FAB type M3)   624  PML/RARA,RARA+
17q21 t(15;17)(q24;q21) Acute promyelocytic leukemia (FAB type M3)   60   
17q21 t(17;17)(q21;q21) Acute promyelocytic leukemia (FAB type M3)   STAT3/RARA,STAT5B/RARA,PRKAR1A/RARA
17q21 t(17;17)(q21;q21) Acute promyelocytic leukemia (FAB type M3)   STAT3/RARA,STAT5B/RARA,PRKAR1A/RARA
17q21 t(1;17)(p36;q21) Acute promyelocytic leukemia (FAB type M3)    
17q21 t(3;17)(p25;q21) Acute promyelocytic leukemia (FAB type M3)   RARA+
17q21 t(3;17)(q26;q21) Acute promyelocytic leukemia (FAB type M3)   FNDC3B/RARA,TBL1XR1/RARA
17q21 t(4;17)(q12;q21) Acute promyelocytic leukemia (FAB type M3)   FIP1L1/RARA
17q21 t(5;17)(q35;q21) Acute promyelocytic leukemia (FAB type M3)   NPM1/RARA
17q22 t(15;17)(q22;q22) Acute promyelocytic leukemia (FAB type M3)    
17q22 t(15;17)(q25;q22) Acute promyelocytic leukemia (FAB type M3)    
17q22 t(15;17)(q26;q22) Acute promyelocytic leukemia (FAB type M3)   12   
21p11 t(21;21)(p11;q11) Acute promyelocytic leukemia (FAB type M3)    
21q11 t(21;21)(p11;q11) Acute promyelocytic leukemia (FAB type M3)    
21q22 t(8;21)(q22;q22) Acute promyelocytic leukemia (FAB type M3)   RUNX1/RUNX1T1
22q11 t(9;22)(q34;q11) Acute promyelocytic leukemia (FAB type M3)   BCR/ABL1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p36 add(1)(p36) Acute promyelocytic leukemia (FAB type M3)    
1q21 add(1)(q21) Acute promyelocytic leukemia (FAB type M3)    
1q21 del(1)(q21) Acute promyelocytic leukemia (FAB type M3)    
2q33 add(2)(q33) Acute promyelocytic leukemia (FAB type M3)    
2q37 add(2)(q37) Acute promyelocytic leukemia (FAB type M3)    
4p16 add(4)(p16) Acute promyelocytic leukemia (FAB type M3)    
5q13 del(5)(q13q33) Acute promyelocytic leukemia (FAB type M3)    
5q33 del(5)(q13q33) Acute promyelocytic leukemia (FAB type M3)    
5q35 add(5)(q35) Acute promyelocytic leukemia (FAB type M3)    
6p21 add(6)(p21) Acute promyelocytic leukemia (FAB type M3)    
6p22 add(6)(p22) Acute promyelocytic leukemia (FAB type M3)    
6p23 add(6)(p23) Acute promyelocytic leukemia (FAB type M3)    
6p25 add(6)(p25) Acute promyelocytic leukemia (FAB type M3)    
6q22 del(6)(q22) Acute promyelocytic leukemia (FAB type M3)    
7q10 i(7)(q10) Acute promyelocytic leukemia (FAB type M3)    
7q22 add(7)(q22) Acute promyelocytic leukemia (FAB type M3)    
7q22 del(7)(q22) Acute promyelocytic leukemia (FAB type M3)    
7q31 add(7)(q31) Acute promyelocytic leukemia (FAB type M3)    
7q32 add(7)(q32) Acute promyelocytic leukemia (FAB type M3)    
7q34 der(7)t(7;8)(q34;q21) Acute promyelocytic leukemia (FAB type M3)    
8p23 add(8)(p23) Acute promyelocytic leukemia (FAB type M3)    
8q10 i(8)(q10) Acute promyelocytic leukemia (FAB type M3)    
8q21 der(7)t(7;8)(q34;q21) Acute promyelocytic leukemia (FAB type M3)    
8q24 add(8)(q24) Acute promyelocytic leukemia (FAB type M3)    
9p22 add(9)(p22) Acute promyelocytic leukemia (FAB type M3)    
9q12 del(9)(q12q22) Acute promyelocytic leukemia (FAB type M3)    
9q12 del(9)(q12q32) Acute promyelocytic leukemia (FAB type M3)    
9q13 del(9)(q13q22) Acute promyelocytic leukemia (FAB type M3)    
9q22 del(9)(q12q22) Acute promyelocytic leukemia (FAB type M3)    
9q22 del(9)(q13q22) Acute promyelocytic leukemia (FAB type M3)    
9q22 del(9)(q22) Acute promyelocytic leukemia (FAB type M3)    
9q32 del(9)(q12q32) Acute promyelocytic leukemia (FAB type M3)    
10q24 del(10)(q24) Acute promyelocytic leukemia (FAB type M3)    
10q26 add(10)(q26) Acute promyelocytic leukemia (FAB type M3)    
11p12 del(11)(p12) Acute promyelocytic leukemia (FAB type M3)    
11p14 del(11)(p14) Acute promyelocytic leukemia (FAB type M3)    
11q23 del(11)(q23) Acute promyelocytic leukemia (FAB type M3)    
12p13 add(12)(p13) Acute promyelocytic leukemia (FAB type M3)    
12p13 del(12)(p13) Acute promyelocytic leukemia (FAB type M3)    
12q12 del(12)(q12q21) Acute promyelocytic leukemia (FAB type M3)    
12q21 del(12)(q12q21) Acute promyelocytic leukemia (FAB type M3)    
13q12 del(13)(q12q14) Acute promyelocytic leukemia (FAB type M3)    
13q14 del(13)(q12q14) Acute promyelocytic leukemia (FAB type M3)    
15p11 add(15)(p11) Acute promyelocytic leukemia (FAB type M3)    
15q22 add(15)(q22) Acute promyelocytic leukemia (FAB type M3)    
15q22 del(15)(q22q26) Acute promyelocytic leukemia (FAB type M3)    
15q22 der(15)t(15;17)(q22;q11) Acute promyelocytic leukemia (FAB type M3)    
15q22 der(15)t(15;17)(q22;q12) Acute promyelocytic leukemia (FAB type M3)   10   
15q22 der(15)t(15;17)(q22;q21) Acute promyelocytic leukemia (FAB type M3)   23   
15q24 der(15)t(15;17)(q24;q21) Acute promyelocytic leukemia (FAB type M3)    
15q26 del(15)(q22q26) Acute promyelocytic leukemia (FAB type M3)    
16p13 add(16)(p13) Acute promyelocytic leukemia (FAB type M3)    
16q13 del(16)(q13) Acute promyelocytic leukemia (FAB type M3)    
16q22 del(16)(q22) Acute promyelocytic leukemia (FAB type M3)    
17p12 del(17)(p12) Acute promyelocytic leukemia (FAB type M3)    
17p13 add(17)(p13) Acute promyelocytic leukemia (FAB type M3)    
17q10 i(17)(q10) Acute promyelocytic leukemia (FAB type M3)   18   
17q10 ider(17)(q10)t(15;17) Acute promyelocytic leukemia (FAB type M3)   53   
17q11 del(17)(q11q21) Acute promyelocytic leukemia (FAB type M3)    
17q11 der(15)t(15;17)(q22;q11) Acute promyelocytic leukemia (FAB type M3)    
17q12 add(17)(q12) Acute promyelocytic leukemia (FAB type M3)    
17q12 der(15)t(15;17)(q22;q12) Acute promyelocytic leukemia (FAB type M3)   10   
17q21 del(17)(q11q21) Acute promyelocytic leukemia (FAB type M3)    
17q21 der(15)t(15;17)(q22;q21) Acute promyelocytic leukemia (FAB type M3)   23   
17q21 der(15)t(15;17)(q24;q21) Acute promyelocytic leukemia (FAB type M3)    
18q23 add(18)(q23) Acute promyelocytic leukemia (FAB type M3)    
19q13 add(19)(q13) Acute promyelocytic leukemia (FAB type M3)    
20q11 del(20)(q11) Acute promyelocytic leukemia (FAB type M3)    
20q11 del(20)(q11q13) Acute promyelocytic leukemia (FAB type M3)    
20q13 del(20)(q11q13) Acute promyelocytic leukemia (FAB type M3)    
20q13 del(20)(q13) Acute promyelocytic leukemia (FAB type M3)    
21p11 add(21)(p11) Acute promyelocytic leukemia (FAB type M3)    
21q10 i(21)(q10) Acute promyelocytic leukemia (FAB type M3)    
21q22 add(21)(q22) Acute promyelocytic leukemia (FAB type M3)    
22p11 add(22)(p11) Acute promyelocytic leukemia (FAB type M3)    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+4 Acute promyelocytic leukemia (FAB type M3)    
+6 Acute promyelocytic leukemia (FAB type M3)    
+7 Acute promyelocytic leukemia (FAB type M3)    
+8 Acute promyelocytic leukemia (FAB type M3)   208   
+9 Acute promyelocytic leukemia (FAB type M3)    
+10 Acute promyelocytic leukemia (FAB type M3)    
+11 Acute promyelocytic leukemia (FAB type M3)    
+13 Acute promyelocytic leukemia (FAB type M3)    
+15 Acute promyelocytic leukemia (FAB type M3)    
+16 Acute promyelocytic leukemia (FAB type M3)    
+17 Acute promyelocytic leukemia (FAB type M3)    
+18 Acute promyelocytic leukemia (FAB type M3)    
+19 Acute promyelocytic leukemia (FAB type M3)    
+21 Acute promyelocytic leukemia (FAB type M3)   26   
+22 Acute promyelocytic leukemia (FAB type M3)    
+X Acute promyelocytic leukemia (FAB type M3)    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Acute promyelocytic leukemia (FAB type M3)    
-2 Acute promyelocytic leukemia (FAB type M3)    
-3 Acute promyelocytic leukemia (FAB type M3)    
-4 Acute promyelocytic leukemia (FAB type M3)    
-5 Acute promyelocytic leukemia (FAB type M3)    
-6 Acute promyelocytic leukemia (FAB type M3)    
-7 Acute promyelocytic leukemia (FAB type M3)   19   
-8 Acute promyelocytic leukemia (FAB type M3)    
-9 Acute promyelocytic leukemia (FAB type M3)   11   
-10 Acute promyelocytic leukemia (FAB type M3)    
-11 Acute promyelocytic leukemia (FAB type M3)    
-12 Acute promyelocytic leukemia (FAB type M3)    
-13 Acute promyelocytic leukemia (FAB type M3)    
-14 Acute promyelocytic leukemia (FAB type M3)    
-15 Acute promyelocytic leukemia (FAB type M3)    
-16 Acute promyelocytic leukemia (FAB type M3)   12   
-17 Acute promyelocytic leukemia (FAB type M3)   11   
-18 Acute promyelocytic leukemia (FAB type M3)   13   
-19 Acute promyelocytic leukemia (FAB type M3)    
-20 Acute promyelocytic leukemia (FAB type M3)    
-21 Acute promyelocytic leukemia (FAB type M3)   10   
-22 Acute promyelocytic leukemia (FAB type M3)    
-X Acute promyelocytic leukemia (FAB type M3)    
-Y Acute promyelocytic leukemia (FAB type M3)   27