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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
2p21 t(2;11)(p21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A+
3q21 inv(3)(q21q26) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18  MECOM+
3q21 t(3;3)(q21;q26) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   RPN1/EVI1,RPN1/MECOM
3q26 inv(3)(q21q26) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18  MECOM+
3q26 t(3;12)(q26;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   ETV6/MECOM
3q26 t(3;3)(q21;q26) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   RPN1/EVI1,RPN1/MECOM
4q11 t(4;12)(q11;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
4q12 t(4;12)(q12;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   CHIC2/ETV6
4q21 t(4;11)(q21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/AFF1
7p22 t(7;21)(p22;q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   RUNX1/USP42
7q36 t(7;12)(q36;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   ETV6+,MNX1/ETV6
8q22 t(8;21)(q22;q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   RUNX1/RUNX1T1
8q24 t(8;14)(q24;q32) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
9p21 t(9;11)(p21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT3,KMT2A+
9p22 t(9;11)(p22;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
9q34 t(9;22)(q34;11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
9q34 t(9;22)(q34;q11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   11  BCR/ABL1
10p12 ins(10;11)(p12;q23q13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT10
10p12 t(10;11)(p12;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT10
10p13 t(10;11)(p13;q21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
10p15 t(10;17)(p15;q21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   MBTD1/ZMYND11,ZMYND11/MBTD1
11q13 ins(10;11)(p12;q23q13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT10
11q21 t(10;11)(p13;q21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 ins(10;11)(p12;q23q13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT10
11q23 t(10;11)(p12;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT10
11q23 t(11;17)(q23;q25) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/SEPT9
11q23 t(11;19)(q23;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT1,KMT2A+
11q23 t(2;11)(p21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A+
11q23 t(4;11)(q21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/AFF1
11q23 t(9;11)(p21;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT3,KMT2A+
11q23 t(9;11)(p22;q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p13 t(12;22)(p13;q12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   MN1/ETV6
12p13 t(3;12)(q26;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   ETV6/MECOM
12p13 t(4;12)(q11;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p13 t(4;12)(q12;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   CHIC2/ETV6
12p13 t(7;12)(q36;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   ETV6+,MNX1/ETV6
14q32 t(8;14)(q24;q32) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
16p13 inv(16)(p13q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   CBFB/MYH11
16q22 inv(16)(p13q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   CBFB/MYH11
17q21 t(10;17)(p15;q21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   MBTD1/ZMYND11,ZMYND11/MBTD1
17q25 t(11;17)(q23;q25) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/SEPT9
19p13 t(11;19)(q23;p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A/MLLT1,KMT2A+
21q22 t(7;21)(p22;q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   RUNX1/USP42
21q22 t(8;21)(q22;q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   RUNX1/RUNX1T1
22q11 t(9;22)(q34;q11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   11  BCR/ABL1
22q12 t(12;22)(p13;q12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   MN1/ETV6

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p13 del(1)(p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
1p36 add(1)(p36) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
1q10 der(1;7)(q10;p10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
1q32 del(1)(q32) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
3p11 del(3)(p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
3p21 del(3)(p21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
3p25 add(3)(p25) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
3q21 del(3)(q21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
3q21 del(3)(q21q26) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
3q26 del(3)(q21q26) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q11 idic(5)(q11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q12 del(5)(q12q34) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q13 del(5)(q13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q13 del(5)(q13q31) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   10   
5q13 del(5)(q13q33) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   14   
5q13 del(5)(q13q34) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q14 del(5)(q14q32) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q15 del(5)(q15) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q15 del(5)(q15q33) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q21 del(5)(q21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q22 del(5)(q22q33) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q31 del(5)(q13q31) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   10   
5q31 del(5)(q31q33) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q32 del(5)(q14q32) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q33 del(5)(q13q33) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   14   
5q33 del(5)(q15q33) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q33 del(5)(q22q33) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q33 del(5)(q31q33) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q34 del(5)(q12q34) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
5q34 del(5)(q13q34) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
6p21 add(6)(p21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
6p22 del(6)(p22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
6p22 der(9)t(6;9)(p22;q34) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7p10 der(1;7)(q10;p10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7p22 add(7)(p22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q10 i(7)(q10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q11 add(7)(q11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q11 del(7)(q11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q11 dic(7;11)(q11;p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q22 add(7)(q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q22 del(7)(q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q22 del(7)(q22q31) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q22 del(7)(q22q36) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q31 del(7)(q22q31) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q31 del(7)(q31) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q32 del(7)(q32) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q36 del(7)(q22q36) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
8q10 i(8)(q10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
9q34 der(9)t(6;9)(p22;q34) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11p11 del(11)(p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11p11 dic(7;11)(q11;p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11p15 add(11)(p15) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q10 der(11;15)(q10;q10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q10 i(11)(q10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q13 del(11)(q13q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q13 der(17)t(11;17)(q13;p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q21 del(11)(q21) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q21 del(11)(q21q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 add(11)(q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 del(11)(q13q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 del(11)(q21q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
11q23 del(11)(q23) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   KMT2A+
11q25 add(11)(q25) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p11 add(12)(p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p11 del(12)(p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p12 add(12)(p12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p12 del(12)(p12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p12 del(12)(p12p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p13 add(12)(p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p13 del(12)(p12p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
12p13 del(12)(p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
13q12 del(13)(q12q14) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
13q14 del(13)(q12q14) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
13q34 add(13)(q34) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
15q10 der(11;15)(q10;q10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
16p11 der(16)del(16)(p11)del(16)(q12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
16q12 del(16)(q12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
16q12 der(16)del(16)(p11)del(16)(q12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
17p11 add(17)(p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
17p11 del(17)(p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
17p11 der(17)t(11;17)(q13;p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
17p13 add(17)(p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
17q10 i(17)(q10) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   12   
17q25 add(17)(q25) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
18p11 add(18)(p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
20p13 add(20)(p13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
20q11 del(20)(q11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
20q12 del(20)(q12) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
20q13 del(20)(q13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
21q22 del(21)(q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
22q13 add(22)(q13) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   13   
+2 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+3 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+4 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   26   
+5 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+6 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   11   
+7 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+8 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   72   
+9 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   10   
+10 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   12   
+11 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
+12 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+13 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   85   
+14 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   13   
+15 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+16 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+17 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+18 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
+19 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   37   
+20 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   10   
+21 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   30   
+22 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
+X Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   11   
+Y Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-2 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-3 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   21   
-4 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-5 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   30   
-6 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-7 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   85   
-8 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-9 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-10 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-11 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-12 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   17   
-13 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   13   
-14 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   14   
-15 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   19   
-16 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
-17 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   41   
-18 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   19   
-19 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-20 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
-21 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   18   
-22 Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
-X Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   15   
-Y Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   17