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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
8q24 t(8;22)(q24;q11) Acute undifferentiated leukemia    
9q34 t(9;22)(q34;q11) Acute undifferentiated leukemia   BCR/ABL1,BCR+
11q23 t(11;19)(q23;p13) Acute undifferentiated leukemia   KMT2A+
19p13 t(11;19)(q23;p13) Acute undifferentiated leukemia   KMT2A+
22q11 t(8;22)(q24;q11) Acute undifferentiated leukemia    
22q11 t(9;22)(q34;q11) Acute undifferentiated leukemia   BCR/ABL1,BCR+

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
5q12 del(5)(q12q31) Acute undifferentiated leukemia    
5q13 del(5)(q13) Acute undifferentiated leukemia    
5q13 del(5)(q13q31) Acute undifferentiated leukemia    
5q13 del(5)(q13q33) Acute undifferentiated leukemia    
5q31 del(5)(q12q31) Acute undifferentiated leukemia    
5q31 del(5)(q13q31) Acute undifferentiated leukemia    
5q33 del(5)(q13q33) Acute undifferentiated leukemia    
7q10 i(7)(q10) Acute undifferentiated leukemia    
20q12 del(20)(q12) Acute undifferentiated leukemia    

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+4 Acute undifferentiated leukemia    
+6 Acute undifferentiated leukemia    
+7 Acute undifferentiated leukemia    
+8 Acute undifferentiated leukemia   13   
+9 Acute undifferentiated leukemia    
+10 Acute undifferentiated leukemia    
+12 Acute undifferentiated leukemia    
+13 Acute undifferentiated leukemia   12   
+19 Acute undifferentiated leukemia    
+21 Acute undifferentiated leukemia    
+22 Acute undifferentiated leukemia    
+X Acute undifferentiated leukemia    

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-4 Acute undifferentiated leukemia    
-7 Acute undifferentiated leukemia    
-9 Acute undifferentiated leukemia    
-11 Acute undifferentiated leukemia    
-14 Acute undifferentiated leukemia    
-17 Acute undifferentiated leukemia    
-19 Acute undifferentiated leukemia    
-20 Acute undifferentiated leukemia    
-21 Acute undifferentiated leukemia    
-22 Acute undifferentiated leukemia    
-X Acute undifferentiated leukemia    
-Y Acute undifferentiated leukemia