Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Chromosomes
  • Tools
  • Genetic and Physical SNP Maps
  • SNP500Cancer
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p22 t(1;14)(p22;q32) Extranodal marginal zone B-cell lymphoma Unknown site IGH/BCL10
11q21 t(11;18)(q21;q21) Extranodal marginal zone B-cell lymphoma Unknown site  
11q23 t(11;22)(q23;q11) Ewing sarcoma Unknown site  
11q24 t(11;22)(q24;q12) Ewing sarcoma Unknown site EWSR1/FLI1,EWSR1+
14q32 t(1;14)(p22;q32) Extranodal marginal zone B-cell lymphoma Unknown site IGH/BCL10
18q11 t(X;18)(p11;q11) Synovial sarcoma Unknown site  
18q21 t(11;18)(q21;q21) Extranodal marginal zone B-cell lymphoma Unknown site  
22q11 t(11;22)(q23;q11) Ewing sarcoma Unknown site  
22q12 t(11;22)(q24;q12) Ewing sarcoma Unknown site EWSR1/FLI1,EWSR1+
Xp11 t(X;18)(p11;q11) Synovial sarcoma Unknown site  

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p13 del(1)(p13) Malignant melanoma Unknown site  
1p22 del(1)(p22) Malignant melanoma Unknown site  
1p31 del(1)(p31) Malignant melanoma Unknown site  
1p36 add(1)(p36) Malignant melanoma Unknown site  
1q10 i(1)(q10) Malignant melanoma Unknown site  
1q11 add(1)(q11) Malignant melanoma Unknown site  
1q11 der(6)t(1;6)(q11;q11) Malignant melanoma Unknown site  
3p11 add(3)(p11) Malignant melanoma Unknown site  
5p10 i(5)(p10) Malignant melanoma Unknown site  
5p15 add(5)(p15) Malignant melanoma Unknown site  
5q14 der(19)t(5;19)(q14;p13) Ewing sarcoma Unknown site  
6p10 i(6)(p10) Malignant melanoma Unknown site  
6q11 add(6)(q11) Malignant melanoma Unknown site  
6q11 der(6)t(1;6)(q11;q11) Malignant melanoma Unknown site  
6q15 del(6)(q15) Adenocarcinoma Unknown site  
6q21 del(6)(q21) Malignant melanoma Unknown site  
7p11 del(7)(p11) Malignant melanoma Unknown site  
7q10 i(7)(q10) Malignant melanoma Unknown site  
8p23 add(8)(p23) Malignant melanoma Unknown site  
8q10 i(8)(q10) Malignant melanoma Unknown site  
9p22 del(9)(p22) Malignant melanoma Unknown site  
10q24 del(10)(q24) Malignant melanoma Unknown site  
11q23 del(11)(q23) Malignant melanoma Unknown site  
12p11 add(12)(p11) Malignant melanoma Unknown site  
12q24 add(12)(q24) Malignant melanoma Unknown site  
13p11 add(13)(p11) Malignant melanoma Unknown site  
13p13 add(13)(p13) Malignant melanoma Unknown site  
13q10 i(13)(q10) Malignant melanoma Unknown site  
13q22 del(13)(q22) Adenocarcinoma Unknown site  
15p13 add(15)(p13) Malignant melanoma Unknown site  
16p13 add(16)(p13) Malignant melanoma Unknown site  
17q10 i(17)(q10) Primitive neuroectodermal tumor/Medulloblastoma Unknown site  
19p13 der(19)t(5;19)(q14;p13) Ewing sarcoma Unknown site  
19q13 add(19)(q13) Malignant melanoma Unknown site  
21p13 add(21)(p13) Malignant melanoma Unknown site  
21q22 add(21)(q22) Neuroblastoma Unknown site  
22q11 del(22)(q11) Ewing sarcoma Unknown site  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Ewing sarcoma Unknown site  
+1 Malignant melanoma Unknown site  
+2 Ewing sarcoma Unknown site  
+2 Malignant melanoma Unknown site  
+3 Extranodal marginal zone B-cell lymphoma Unknown site  
+3 Malignant melanoma Unknown site  
+3 Neuroblastoma Unknown site  
+4 Ewing sarcoma Unknown site  
+5 Ewing sarcoma Unknown site  
+5 Malignant melanoma Unknown site  
+6 Malignant melanoma Unknown site  
+7 Adenocarcinoma Unknown site  
+7 Ewing sarcoma Unknown site  
+7 Malignant melanoma Unknown site 17   
+8 Ewing sarcoma Unknown site  
+8 Malignant melanoma Unknown site  
+9 Ewing sarcoma Unknown site  
+12 Ewing sarcoma Unknown site  
+12 Malignant melanoma Unknown site  
+12 Neuroblastoma Unknown site  
+13 Malignant melanoma Unknown site  
+14 Ewing sarcoma Unknown site  
+15 Ewing sarcoma Unknown site  
+15 Malignant melanoma Unknown site  
+16 Malignant melanoma Unknown site  
+17 Malignant melanoma Unknown site  
+17 Neuroblastoma Unknown site  
+18 Ewing sarcoma Unknown site  
+18 Extranodal marginal zone B-cell lymphoma Unknown site  
+18 Malignant melanoma Unknown site  
+18 Neuroblastoma Unknown site  
+19 Malignant melanoma Unknown site  
+20 Ewing sarcoma Unknown site  
+20 Malignant melanoma Unknown site 11   
+21 Malignant melanoma Unknown site  
+22 Malignant melanoma Unknown site  
+X Malignant melanoma Unknown site  

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Malignant melanoma Unknown site  
-2 Malignant melanoma Unknown site 12   
-3 Malignant melanoma Unknown site  
-4 Ewing sarcoma Unknown site  
-4 Malignant melanoma Unknown site 12   
-5 Ewing sarcoma Unknown site  
-5 Malignant melanoma Unknown site 11   
-6 Malignant melanoma Unknown site  
-6 Osteosarcoma, NOS Unknown site  
-7 Ewing sarcoma Unknown site  
-8 Adenocarcinoma Unknown site  
-8 Malignant melanoma Unknown site 13   
-9 Adenocarcinoma Unknown site  
-9 Malignant melanoma Unknown site 21   
-10 Malignant melanoma Unknown site 34   
-10 Neuroblastoma Unknown site  
-10 Osteosarcoma, NOS Unknown site  
-11 Ewing sarcoma Unknown site  
-11 Malignant melanoma Unknown site 18   
-12 Malignant melanoma Unknown site  
-13 Malignant melanoma Unknown site 14   
-13 Neuroblastoma Unknown site  
-13 Osteosarcoma, NOS Unknown site  
-14 Adenocarcinoma Unknown site  
-14 Malignant melanoma Unknown site 13   
-14 Neuroblastoma Unknown site  
-14 Synovial sarcoma Unknown site  
-15 Ewing sarcoma Unknown site  
-15 Malignant melanoma Unknown site 11   
-16 Adenocarcinoma Unknown site  
-16 Malignant melanoma Unknown site 15   
-16 Osteosarcoma, NOS Unknown site  
-17 Malignant melanoma Unknown site 12   
-18 Adenocarcinoma Unknown site  
-18 Malignant melanoma Unknown site 12   
-19 Malignant melanoma Unknown site 13   
-20 Ewing sarcoma Unknown site  
-20 Malignant melanoma Unknown site  
-21 Adenocarcinoma Unknown site  
-21 Extranodal marginal zone B-cell lymphoma Unknown site  
-21 Malignant melanoma Unknown site 13   
-22 Ewing sarcoma Unknown site  
-22 Malignant melanoma Unknown site 20   
-22 Meningioma Unknown site  
-22 Neuroblastoma Unknown site  
-22 Schwannoma Unknown site  
-X Malignant melanoma Unknown site 12   
-Y Adenocarcinoma Unknown site  
-Y Malignant melanoma Unknown site 16   
-Y Neuroblastoma Unknown site