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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
2p13 t(2;19)(p13;q13) Nonneoplastic epithelial disorder/lesion Thyroid  
2q13 t(2;3)(q13;p25) Adenocarcinoma Thyroid PAX8/PPARG
2q13 t(2;3)(q13;p25) Adenoma Thyroid PAX8/PPARG
3p25 t(2;3)(q13;p25) Adenocarcinoma Thyroid PAX8/PPARG
3p25 t(2;3)(q13;p25) Adenoma Thyroid PAX8/PPARG
5q13 t(5;19)(q13;q13) Adenoma Thyroid ZNF331+
5q13 t(5;19)(q13;q13) Nonneoplastic epithelial disorder/lesion Thyroid  
7q35 t(7;10)(q35;q21) Adenocarcinoma Thyroid  
10q11 inv(10)(q11q21) Adenocarcinoma Thyroid CCDC6/RET
10q21 inv(10)(q11q21) Adenocarcinoma Thyroid CCDC6/RET
10q21 t(7;10)(q35;q21) Adenocarcinoma Thyroid  
14p13 tas(14;21)(p13;p13) Nonneoplastic epithelial disorder/lesion Thyroid  
15p13 tas(15;22)(p13;p13) Nonneoplastic epithelial disorder/lesion Thyroid  
19q13 t(2;19)(p13;q13) Nonneoplastic epithelial disorder/lesion Thyroid  
19q13 t(5;19)(q13;q13) Adenoma Thyroid ZNF331+
19q13 t(5;19)(q13;q13) Nonneoplastic epithelial disorder/lesion Thyroid  
21p13 tas(14;21)(p13;p13) Nonneoplastic epithelial disorder/lesion Thyroid  
22p13 tas(15;22)(p13;p13) Nonneoplastic epithelial disorder/lesion Thyroid  

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q31 del(1)(q31) Undifferentiated carcinoma Thyroid  
9p22 add(9)(p22) Adenocarcinoma Thyroid  
10p13 add(10)(p13) Adenocarcinoma Thyroid  
11p15 add(11)(p15) Hyperplasia Thyroid  
11q13 del(11)(q13q13) Adenoma Thyroid  
11q13 del(11)(q13q13) Adenoma Thyroid  
12p11 del(12)(p11) Adenocarcinoma Thyroid  
12q24 add(12)(q24) Adenocarcinoma Thyroid  
13q10 i(13)(q10) Undifferentiated carcinoma Thyroid  
18p11 del(18)(p11) Hyperplasia Thyroid  
19q13 add(19)(q13) Nonneoplastic epithelial disorder/lesion Thyroid  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+2 Adenocarcinoma Thyroid  
+3 Extranodal marginal zone B-cell lymphoma Thyroid  
+4 Adenoma Thyroid 12   
+5 Adenocarcinoma Thyroid  
+5 Adenoma Thyroid 20   
+5 Hyperplasia Thyroid  
+6 Adenocarcinoma Thyroid  
+6 Adenoma Thyroid  
+7 Adenocarcinoma Thyroid 23   
+7 Adenoma Thyroid 34   
+7 Hyperplasia Thyroid  
+7 Nonneoplastic epithelial disorder/lesion Thyroid 12   
+8 Adenoma Thyroid  
+8 Hyperplasia Thyroid  
+9 Adenocarcinoma Thyroid  
+9 Adenoma Thyroid 12   
+9 Hyperplasia Thyroid  
+10 Nonneoplastic epithelial disorder/lesion Thyroid  
+11 Adenoma Thyroid  
+12 Adenocarcinoma Thyroid  
+12 Adenoma Thyroid 29   
+12 Hyperplasia Thyroid  
+13 Adenocarcinoma Thyroid  
+13 Adenoma Thyroid  
+14 Adenocarcinoma Thyroid  
+14 Adenoma Thyroid  
+15 Hyperplasia Thyroid  
+16 Adenocarcinoma Thyroid  
+16 Adenoma Thyroid 14   
+16 Hyperplasia Thyroid  
+16 Nonneoplastic epithelial disorder/lesion Thyroid  
+17 Adenocarcinoma Thyroid  
+17 Adenoma Thyroid 16   
+17 Nonneoplastic epithelial disorder/lesion Thyroid  
+18 Adenocarcinoma Thyroid  
+18 Adenoma Thyroid  
+18 Hyperplasia Thyroid  
+19 Adenocarcinoma Thyroid  
+19 Adenoma Thyroid  
+20 Adenocarcinoma Thyroid 10   
+20 Adenoma Thyroid 13   
+20 Hyperplasia Thyroid  
+21 Adenocarcinoma Thyroid  
+21 Adenoma Thyroid  
+22 Adenoma Thyroid  
+X Adenocarcinoma Thyroid  
+X Adenoma Thyroid  
+Y Adenocarcinoma Thyroid  

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Adenocarcinoma Thyroid  
-1 Adenoma Thyroid  
-2 Adenocarcinoma Thyroid  
-2 Adenoma Thyroid  
-2 Nonneoplastic epithelial disorder/lesion Thyroid  
-3 Adenocarcinoma Thyroid  
-3 Nonneoplastic epithelial disorder/lesion Thyroid  
-4 Adenocarcinoma Thyroid  
-5 Adenocarcinoma Thyroid  
-6 Adenocarcinoma Thyroid  
-6 Adenoma Thyroid  
-6 Extranodal marginal zone B-cell lymphoma Thyroid  
-7 Adenocarcinoma Thyroid  
-8 Adenocarcinoma Thyroid 11   
-8 Adenoma Thyroid  
-9 Adenocarcinoma Thyroid  
-10 Adenocarcinoma Thyroid  
-10 Adenoma Thyroid  
-11 Adenocarcinoma Thyroid 11   
-11 Adenoma Thyroid  
-12 Adenocarcinoma Thyroid  
-13 Adenocarcinoma Thyroid 11   
-13 Adenoma Thyroid  
-13 Nonneoplastic epithelial disorder/lesion Thyroid  
-13 Undifferentiated carcinoma Thyroid  
-14 Adenocarcinoma Thyroid  
-14 Undifferentiated carcinoma Thyroid  
-15 Adenocarcinoma Thyroid  
-15 Adenoma Thyroid  
-16 Adenocarcinoma Thyroid  
-16 Adenoma Thyroid  
-16 Undifferentiated carcinoma Thyroid  
-17 Adenocarcinoma Thyroid 11   
-17 Adenoma Thyroid  
-17 Undifferentiated carcinoma Thyroid  
-18 Adenocarcinoma Thyroid 12   
-18 Adenoma Thyroid  
-19 Adenocarcinoma Thyroid  
-19 Adenoma Thyroid  
-19 Undifferentiated carcinoma Thyroid  
-20 Adenocarcinoma Thyroid  
-20 Adenoma Thyroid  
-20 Extranodal marginal zone B-cell lymphoma Thyroid  
-20 Nonneoplastic epithelial disorder/lesion Thyroid  
-21 Adenocarcinoma Thyroid 11   
-21 Adenoma Thyroid  
-21 Nonneoplastic epithelial disorder/lesion Thyroid  
-22 Adenocarcinoma Thyroid 12   
-22 Adenoma Thyroid 14   
-22 Nonneoplastic epithelial disorder/lesion Thyroid  
-22 Undifferentiated carcinoma Thyroid  
-X Adenocarcinoma Thyroid  
-X Adenoma Thyroid  
-X Undifferentiated carcinoma Thyroid  
-Y Adenocarcinoma Thyroid 13