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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
2q35 t(2;13)(q35;q14) Alveolar rhabdomyosarcoma Intraabdominal  
11p13 t(11;22)(p13;q12) Desmoplastic small round cell tumor Intraabdominal EWSR1/WT1
11q23 t(11;22)(q23;q11) Peripheral neuroepithelioma Intraabdominal  
11q24 t(11;22)(q24;q12) Ewing sarcoma Intraabdominal  
11q24 t(11;22)(q24;q12) Peripheral neuroepithelioma Intraabdominal  
12q13 t(12;16)(q13;p11) Liposarcoma, myxoid/round cell Intraabdominal  
13q14 t(2;13)(q35;q14) Alveolar rhabdomyosarcoma Intraabdominal  
16p11 t(12;16)(q13;p11) Liposarcoma, myxoid/round cell Intraabdominal  
18q11 t(X;18)(p11;q11) Synovial sarcoma Intraabdominal SS18/SSX1
22q11 t(11;22)(q23;q11) Peripheral neuroepithelioma Intraabdominal  
22q12 t(11;22)(p13;q12) Desmoplastic small round cell tumor Intraabdominal EWSR1/WT1
22q12 t(11;22)(q24;q12) Ewing sarcoma Intraabdominal  
22q12 t(11;22)(q24;q12) Peripheral neuroepithelioma Intraabdominal  
Xp11 t(X;18)(p11;q11) Synovial sarcoma Intraabdominal SS18/SSX1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p22 add(1)(p22) Neuroblastoma Intraabdominal  
1p22 del(1)(p22) Teratoma (mature and immature) Intraabdominal  
1q21 add(1)(q21) Liposarcoma, dedifferentiated Intraabdominal  
1q42 add(1)(q42) Liposarcoma, dedifferentiated Intraabdominal  
3p23 del(3)(p23) Neuroblastoma Intraabdominal  
5p15 add(5)(p15) Liposarcoma, pleomorphic Intraabdominal  
7p22 add(7)(p22) Liposarcoma, dedifferentiated Intraabdominal  
8q10 i(8)(q10) Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
9p22 add(9)(p22) Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
11p15 add(11)(p15) Atypical lipomatous tumor/atypical lipoma/well-differentiated liposarcoma Intraabdominal  
11p15 add(11)(p15) Liposarcoma, dedifferentiated Intraabdominal  
12p11 add(12)(p11) Lipoma Intraabdominal  
12p13 add(12)(p13) Leiomyosarcoma Intraabdominal  
13q32 add(13)(q32) Lipoma Intraabdominal  
14p11 add(14)(p11) Leiomyosarcoma Intraabdominal  
15p11 add(15)(p11) Leiomyosarcoma Intraabdominal  
15p11 add(15)(p11) Seminoma/Dysgerminoma Intraabdominal  
16q24 del(16)(q24) Liposarcoma, dedifferentiated Intraabdominal  
17p11 add(17)(p11) Leiomyosarcoma Intraabdominal  
17p11 add(17)(p11) Liposarcoma, dedifferentiated Intraabdominal  
19q13 add(19)(q13) Inflammatory myofibroblastic tumor/myofibroblastic sarcoma Intraabdominal  
19q13 add(19)(q13) Liposarcoma, dedifferentiated Intraabdominal  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Desmoplastic small round cell tumor Intraabdominal  
+1 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
+1 Teratoma (mature and immature) Intraabdominal  
+2 Alveolar rhabdomyosarcoma Intraabdominal  
+2 Embryonal rhabdomyosarcoma Intraabdominal  
+2 Ewing sarcoma Intraabdominal  
+2 Neuroblastoma Intraabdominal  
+2 Soft tissue tumor, special type Intraabdominal  
+3 Leiomyosarcoma Intraabdominal  
+3 Liposarcoma, myxoid/round cell Intraabdominal  
+3 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
+3 Neuroblastoma Intraabdominal  
+4 Neuroblastoma Intraabdominal  
+5 Desmoplastic small round cell tumor Intraabdominal  
+5 Neuroblastoma Intraabdominal  
+5 Solitary fibrous tumor Intraabdominal  
+6 Gastrointestinal stromal tumor Intraabdominal  
+6 Neuroblastoma Intraabdominal  
+7 Embryonal rhabdomyosarcoma Intraabdominal  
+7 Gastrointestinal stromal tumor Intraabdominal  
+7 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
+7 Neuroblastoma Intraabdominal  
+7 Peripheral neuroepithelioma Intraabdominal  
+7 Teratoma (mature and immature) Intraabdominal  
+8 Alveolar rhabdomyosarcoma Intraabdominal  
+8 Embryonal rhabdomyosarcoma Intraabdominal  
+8 Ewing sarcoma Intraabdominal  
+8 Gastrointestinal stromal tumor Intraabdominal  
+8 Liposarcoma, myxoid/round cell Intraabdominal  
+8 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
+8 Neuroblastoma Intraabdominal  
+8 Soft tissue tumor, special type Intraabdominal  
+9 Neuroblastoma Intraabdominal  
+10 Neuroblastoma Intraabdominal  
+11 Embryonal rhabdomyosarcoma Intraabdominal  
+11 Neuroblastoma Intraabdominal  
+12 Embryonal rhabdomyosarcoma Intraabdominal  
+12 Neuroblastoma Intraabdominal  
+13 Embryonal rhabdomyosarcoma Intraabdominal  
+13 Neuroblastoma Intraabdominal  
+14 Neuroblastoma Intraabdominal  
+15 Neuroblastoma Intraabdominal  
+16 Neuroblastoma Intraabdominal  
+17 Neuroblastoma Intraabdominal  
+18 Desmoplastic small round cell tumor Intraabdominal  
+18 Embryonal rhabdomyosarcoma Intraabdominal  
+18 Neuroblastoma Intraabdominal  
+19 Embryonal rhabdomyosarcoma Intraabdominal  
+19 Neuroblastoma Intraabdominal  
+19 Teratoma (mature and immature) Intraabdominal  
+20 Alveolar rhabdomyosarcoma Intraabdominal  
+20 Embryonal rhabdomyosarcoma Intraabdominal  
+20 Neuroblastoma Intraabdominal  
+21 Neuroblastoma Intraabdominal  
+21 Teratoma (mature and immature) Intraabdominal  
+22 Neuroblastoma Intraabdominal  
+X Leiomyosarcoma Intraabdominal  
+X Teratoma (mature and immature) Intraabdominal  
+Y Neuroblastoma Intraabdominal  

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Gastrointestinal stromal tumor Intraabdominal  
-1 Leiomyosarcoma Intraabdominal  
-1 Neuroblastoma Intraabdominal  
-2 Gastrointestinal stromal tumor Intraabdominal  
-2 Leiomyosarcoma Intraabdominal  
-2 Liposarcoma, dedifferentiated Intraabdominal  
-2 Liposarcoma, pleomorphic Intraabdominal  
-2 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-2 Neuroblastoma Intraabdominal  
-3 Leiomyosarcoma Intraabdominal  
-3 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-3 Neuroblastoma Intraabdominal  
-4 Gastrointestinal stromal tumor Intraabdominal  
-4 Leiomyosarcoma Intraabdominal  
-4 Liposarcoma, pleomorphic Intraabdominal  
-4 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-4 Neuroblastoma Intraabdominal 11   
-4 Seminoma/Dysgerminoma Intraabdominal  
-5 Leiomyosarcoma Intraabdominal  
-5 Liposarcoma, myxoid/round cell Intraabdominal  
-5 Liposarcoma, pleomorphic Intraabdominal  
-5 Neuroblastoma Intraabdominal  
-6 Inflammatory myofibroblastic tumor/myofibroblastic sarcoma Intraabdominal  
-6 Neuroblastoma Intraabdominal  
-7 Leiomyosarcoma Intraabdominal  
-7 Liposarcoma, dedifferentiated Intraabdominal  
-7 Neuroblastoma Intraabdominal  
-8 Leiomyosarcoma Intraabdominal  
-8 Liposarcoma, dedifferentiated Intraabdominal  
-8 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-8 Neuroblastoma Intraabdominal  
-9 Gastrointestinal stromal tumor Intraabdominal  
-9 Liposarcoma, dedifferentiated Intraabdominal  
-9 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-9 Neuroblastoma Intraabdominal  
-10 Gastrointestinal stromal tumor Intraabdominal  
-10 Leiomyosarcoma Intraabdominal  
-10 Liposarcoma, pleomorphic Intraabdominal  
-10 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-10 Neuroblastoma Intraabdominal  
-10 Peripheral neuroepithelioma Intraabdominal  
-11 Gastrointestinal stromal tumor Intraabdominal  
-11 Leiomyosarcoma Intraabdominal  
-11 Liposarcoma, dedifferentiated Intraabdominal  
-11 Liposarcoma, pleomorphic Intraabdominal  
-11 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-11 Neuroblastoma Intraabdominal  
-12 Leiomyosarcoma Intraabdominal  
-12 Liposarcoma, dedifferentiated Intraabdominal  
-12 Liposarcoma, pleomorphic Intraabdominal  
-12 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-13 Alveolar rhabdomyosarcoma Intraabdominal  
-13 Gastrointestinal stromal tumor Intraabdominal  
-13 Leiomyosarcoma Intraabdominal  
-13 Liposarcoma, pleomorphic Intraabdominal  
-13 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-13 Neuroblastoma Intraabdominal  
-14 Atypical lipomatous tumor/atypical lipoma/well-differentiated liposarcoma Intraabdominal  
-14 Gastrointestinal stromal tumor Intraabdominal  
-14 Leiomyosarcoma Intraabdominal  
-14 Liposarcoma, dedifferentiated Intraabdominal  
-14 Liposarcoma, pleomorphic Intraabdominal  
-14 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-14 Neuroblastoma Intraabdominal  
-15 Atypical lipomatous tumor/atypical lipoma/well-differentiated liposarcoma Intraabdominal  
-15 Gastrointestinal stromal tumor Intraabdominal  
-15 Leiomyosarcoma Intraabdominal  
-15 Liposarcoma, pleomorphic Intraabdominal  
-15 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-15 Neuroblastoma Intraabdominal  
-16 Liposarcoma, pleomorphic Intraabdominal  
-16 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-16 Neuroblastoma Intraabdominal  
-17 Leiomyosarcoma Intraabdominal  
-17 Liposarcoma, dedifferentiated Intraabdominal  
-17 Liposarcoma, pleomorphic Intraabdominal  
-17 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-18 Leiomyosarcoma Intraabdominal  
-18 Liposarcoma, pleomorphic Intraabdominal  
-18 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-18 Neuroblastoma Intraabdominal  
-19 Leiomyosarcoma Intraabdominal  
-19 Liposarcoma, dedifferentiated Intraabdominal  
-19 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-19 Neuroblastoma Intraabdominal  
-20 Liposarcoma, dedifferentiated Intraabdominal  
-20 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-20 Neuroblastoma Intraabdominal  
-20 Seminoma/Dysgerminoma Intraabdominal  
-21 Leiomyosarcoma Intraabdominal  
-21 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-21 Neuroblastoma Intraabdominal  
-22 Atypical lipomatous tumor/atypical lipoma/well-differentiated liposarcoma Intraabdominal  
-22 Gastrointestinal stromal tumor Intraabdominal  
-22 Inflammatory myofibroblastic tumor/myofibroblastic sarcoma Intraabdominal  
-22 Leiomyosarcoma Intraabdominal  
-22 Liposarcoma, pleomorphic Intraabdominal  
-22 Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-22 Neuroblastoma Intraabdominal  
-X Gastrointestinal stromal tumor Intraabdominal  

Abnormality Morphology Topography Cases Genes
-X Leiomyosarcoma Intraabdominal  
-X Liposarcoma, dedifferentiated Intraabdominal  
-X Malignant peripheral nerve sheath tumor/Triton Intraabdominal  
-X Neuroblastoma Intraabdominal 12   
-Y Leiomyosarcoma Intraabdominal  
-Y Liposarcoma, dedifferentiated Intraabdominal  
-Y Neuroblastoma Intraabdominal