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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p36 t(1;22)(p36;q11) Rhabdoid tumor Intrathoracal  
2q35 t(2;13)(q35;q14) Rhabdomyosarcoma, NOS Intrathoracal  
2q37 t(2;13)(q37;q14) Alveolar rhabdomyosarcoma Intrathoracal  
11q24 t(11;22)(q24;q12) Ewing sarcoma Intrathoracal  
13q14 t(2;13)(q35;q14) Rhabdomyosarcoma, NOS Intrathoracal  
13q14 t(2;13)(q37;q14) Alveolar rhabdomyosarcoma Intrathoracal  
18q11 t(X;18)(p11;q11) Synovial sarcoma Intrathoracal SS18/SSX1
22q11 t(1;22)(p36;q11) Rhabdoid tumor Intrathoracal  
22q12 t(11;22)(q24;q12) Ewing sarcoma Intrathoracal  
Xp11 t(X;18)(p11;q11) Synovial sarcoma Intrathoracal SS18/SSX1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p13 del(1)(p13) Germ cell tumor, NOS Intrathoracal  
12p10 i(12)(p10) Combined germ cell tumors Intrathoracal  
12p10 i(12)(p10) Germ cell tumor, NOS Intrathoracal  
12p10 i(12)(p10) Seminoma/Dysgerminoma Intrathoracal  
12p10 i(12)(p10) Teratoma (mature and immature) Intrathoracal  

Numerical Chromosomal Trisomy Abnormalities

Abnormality Morphology Topography Cases Genes
+1 Teratoma (mature and immature) Intrathoracal  
+2 Teratoma (mature and immature) Intrathoracal  
+3 Combined germ cell tumors Intrathoracal  
+5 Ewing sarcoma Intrathoracal  
+7 Teratoma (mature and immature) Intrathoracal  
+8 Combined germ cell tumors Intrathoracal  
+8 Ewing sarcoma Intrathoracal  
+8 Neuroblastoma Intrathoracal  
+8 Teratoma (mature and immature) Intrathoracal  
+9 Neuroblastoma Intrathoracal  
+10 Germ cell tumor, NOS Intrathoracal  
+12 Ewing sarcoma Intrathoracal  
+13 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
+17 Combined germ cell tumors Intrathoracal  
+20 Teratoma (mature and immature) Intrathoracal  
+21 Combined germ cell tumors Intrathoracal  
+21 Teratoma (mature and immature) Intrathoracal  
+22 Teratoma (mature and immature) Intrathoracal  

Numerical Chromosomal Monosomy Abnormalities

Abnormality Morphology Topography Cases Genes
-1 Teratoma (mature and immature) Intrathoracal  
-2 Teratoma (mature and immature) Intrathoracal  
-3 Seminoma/Dysgerminoma Intrathoracal  
-4 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
-4 Peripheral neuroepithelioma Intrathoracal  
-4 Seminoma/Dysgerminoma Intrathoracal  
-5 Combined germ cell tumors Intrathoracal  
-5 Teratoma (mature and immature) Intrathoracal  
-9 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
-10 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
-10 Neuroblastoma Intrathoracal  
-11 Neuroblastoma Intrathoracal  
-12 Neuroblastoma Intrathoracal  
-13 Combined germ cell tumors Intrathoracal  
-13 Seminoma/Dysgerminoma Intrathoracal  
-13 Teratoma (mature and immature) Intrathoracal  
-14 Germ cell tumor, NOS Intrathoracal  
-14 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
-14 Teratoma (mature and immature) Intrathoracal  
-15 Combined germ cell tumors Intrathoracal  
-15 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
-15 Peripheral neuroepithelioma Intrathoracal  
-16 Seminoma/Dysgerminoma Intrathoracal  
-17 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
-18 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
-20 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
-22 Germ cell tumor, NOS Intrathoracal  
-22 Malignant peripheral nerve sheath tumor/Triton Intrathoracal  
-X Malignant peripheral nerve sheath tumor/Triton Intrathoracal