Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Chromosomes
  • Tools
  • Genetic and Physical SNP Maps
  • SNP500Cancer
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7q22 inv(7)(p11q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 inv(7)(p15q22) Chronic myeloid leukemia, t(9;22)    
7q22 inv(7)(q22q34) Acute myeloid leukemia, NOS    
7q22 t(1;7)(p36;q22) Chronic myeloid leukemia, t(9;22)    
7q22 t(1;7)(q42;q22) Leiomyoma Uterus, corpus  
7q22 t(2;7)(p11;q22) Chronic lymphocytic leukemia    
7q22 t(2;7)(p11;q22) Mature B-cell neoplasm, NOS    
7q22 t(2;7)(p11;q22) Splenic marginal zone B-cell lymphoma    
7q22 t(6;7)(p21;q22) Follicular lymphoma    
7q22 t(7;10)(q22;q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 t(7;11)(q22;q13) Acute myeloid leukemia, NOS    
7q22 t(7;12)(q22;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   ETV6+
7q22 t(7;14)(q22;q32) Multiple myeloma    
7q22 t(7;15)(q22;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 t(7;22)(q22;q11) Chronic myeloid leukemia, aberrant translocation   BCR+
7q22 t(7;7)(p22;q22) Chronic myeloid leukemia, aberrant translocation    
7q22 t(7;8)(q22;q13) Chronic myeloid leukemia, t(9;22)    
7q22 t(7;9;22)(q22;q34;q11) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7q22 add(7)(q22) Acute erythroleukemia (FAB type M6)    
7q22 add(7)(q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma   11   
7q22 add(7)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
7q22 add(7)(q22) Acute monoblastic leukemia (FAB type M5)    
7q22 add(7)(q22) Acute monoblastic leukemia without differentiation (FAB type M5a)    
7q22 add(7)(q22) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q22 add(7)(q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q22 add(7)(q22) Acute myeloid leukemia, NOS   19   
7q22 add(7)(q22) Acute myelomonocytic leukemia (FAB type M4)    
7q22 add(7)(q22) Acute promyelocytic leukemia (FAB type M3)    
7q22 add(7)(q22) Adenocarcinoma Stomach  
7q22 add(7)(q22) Adenocarcinoma Ovary  
7q22 add(7)(q22) Adenocarcinoma Breast  
7q22 add(7)(q22) Adult T-cell lymphoma/leukemia (HTLV-1+)    
7q22 add(7)(q22) Astrocytoma, grade III-IV/Glioblastoma Brain  
7q22 add(7)(q22) Burkitt lymphoma/leukemia    
7q22 add(7)(q22) Chronic myeloid leukemia, aberrant translocation    
7q22 add(7)(q22) Diffuse large B-cell lymphoma    
7q22 add(7)(q22) Diffuse large B-cell lymphoma Testis  
7q22 add(7)(q22) Follicular lymphoma    
7q22 add(7)(q22) Juvenile myelomonocytic leukemia    
7q22 add(7)(q22) Leiomyosarcoma Soft tissue  
7q22 add(7)(q22) Malignant epithelial tumor, special type Salivary gland  
7q22 add(7)(q22) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
7q22 add(7)(q22) Mature B-cell neoplasm, NOS    
7q22 add(7)(q22) Mature T- and NK-cell neoplasm, NOS    
7q22 add(7)(q22) Multiple myeloma    
7q22 add(7)(q22) Myelodysplastic syndrome, NOS    
7q22 add(7)(q22) Osteosarcoma, NOS Skeleton  
7q22 add(7)(q22) Seminoma/Dysgerminoma Testis  
7q22 add(7)(q22) Squamous cell carcinoma Oral cavity  
7q22 add(7)(q22) T-prolymphocytic leukemia    
7q22 add(7)(q22) Teratoma (mature and immature) Testis  
7q22 del(7)(q11q22) Acute erythroleukemia (FAB type M6)    
7q22 del(7)(q11q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 del(7)(q11q22) Acute myeloid leukemia, NOS    
7q22 del(7)(q11q22) Follicular lymphoma    
7q22 del(7)(q11q22) Refractory anemia with excess of blasts (FAB)    
7q22 del(7)(q11q22) Squamous cell carcinoma Lung  
7q22 del(7)(q21q22) Adenocarcinoma Lung  
7q22 del(7)(q21q22) Leiomyoma Uterus, corpus  
7q22 del(7)(q22) Acute erythroleukemia (FAB type M6)   10   
7q22 del(7)(q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma   33   
7q22 del(7)(q22) Acute megakaryoblastic leukemia (FAB type M7)    
7q22 del(7)(q22) Acute monoblastic leukemia (FAB type M5)    
7q22 del(7)(q22) Acute monoblastic leukemia without differentiation (FAB type M5a)    
7q22 del(7)(q22) Acute myeloblastic leukemia with maturation (FAB type M2)   30   
7q22 del(7)(q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q22 del(7)(q22) Acute myeloblastic leukemia without maturation (FAB type M1)   13   
7q22 del(7)(q22) Acute myeloid leukemia, NOS   84   
7q22 del(7)(q22) Acute myelomonocytic leukemia (FAB type M4)   22   
7q22 del(7)(q22) Acute promyelocytic leukemia (FAB type M3)    
7q22 del(7)(q22) Adenocarcinoma Kidney  
7q22 del(7)(q22) Adenocarcinoma Prostate  
7q22 del(7)(q22) Adenocarcinoma Uterus, corpus  
7q22 del(7)(q22) Adenocarcinoma Stomach  
7q22 del(7)(q22) Adenocarcinoma Lung  
7q22 del(7)(q22) Adenocarcinoma Breast  
7q22 del(7)(q22) Adenocarcinoma Ovary  
7q22 del(7)(q22) Astrocytoma, grade III-IV/Glioblastoma Brain  
7q22 del(7)(q22) Bilineage or biphenotypic leukemia    
7q22 del(7)(q22) Carcinoma, NOS Breast  
7q22 del(7)(q22) Chondrosarcoma, NOS Skeleton  
7q22 del(7)(q22) Chronic lymphocytic leukemia    
7q22 del(7)(q22) Chronic myeloid leukemia, aberrant translocation    
7q22 del(7)(q22) Chronic myeloid leukemia, t(9;22)   11   
7q22 del(7)(q22) Chronic myelomonocytic leukemia    
7q22 del(7)(q22) Combined germ cell tumors Testis  
7q22 del(7)(q22) Diffuse large B-cell lymphoma   13   
7q22 del(7)(q22) Extranodal marginal zone B-cell lymphoma Stomach  
7q22 del(7)(q22) Follicular lymphoma   21   
7q22 del(7)(q22) Hodgkin disease, nodular sclerosis    
7q22 del(7)(q22) Idiopathic myelofibrosis    
7q22 del(7)(q22) Leiomyoma Uterus, corpus 13   
7q22 del(7)(q22) Leiomyosarcoma Soft tissue  
7q22 del(7)(q22) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
7q22 del(7)(q22) Mantle cell lymphoma    
7q22 del(7)(q22) Mature B-cell neoplasm, NOS    
7q22 del(7)(q22) Mesothelioma Pleura  
7q22 del(7)(q22) Multiple myeloma   11   
7q22 del(7)(q22) Myelodysplastic syndrome, NOS   21   
7q22 del(7)(q22) Neuroglial neoplasm, special type Brain  
7q22 del(7)(q22) Osteosarcoma, NOS Skeleton  
7q22 del(7)(q22) Polycythemia vera    
7q22 del(7)(q22) Refractory anemia   16   
7q22 del(7)(q22) Refractory anemia with excess blasts-1    
7q22 del(7)(q22) Refractory anemia with excess blasts-2    
7q22 del(7)(q22) Refractory anemia with excess of blasts (FAB)   26   
7q22 del(7)(q22) Refractory anemia with ringed sideroblasts    
7q22 del(7)(q22) Refractory cytopenia with multilineage dysplasia    
7q22 del(7)(q22) Splenic marginal zone B-cell lymphoma    
7q22 del(7)(q22) Squamous cell carcinoma Lung  
7q22 del(7)(q22) Squamous cell carcinoma Oral cavity  
7q22 del(7)(q22) Teratoma (mature and immature) Testis  
7q22 del(7)(q22) Transitional cell carcinoma Bladder  
7q22 del(7)(q22) Undifferentiated pleomorphic sarcoma Soft tissue  
7q22 del(7)(q22q22) Chronic myeloid leukemia, t(9;22)    
7q22 del(7)(q22q22) Chronic myeloid leukemia, t(9;22)    
7q22 del(7)(q22q31) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 del(7)(q22q31) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    

Band Abnormality Morphology Topography Cases Genes
7q22 del(7)(q22q31) Acute myeloid leukemia, NOS    
7q22 del(7)(q22q31) Leiomyoma Uterus, corpus  
7q22 del(7)(q22q31) Myelodysplastic syndrome, NOS    
7q22 del(7)(q22q31)ordel(7)(q11q22) Leiomyoma Uterus, corpus  
7q22 del(7)(q22q31)ordel(7)(q11q22) Leiomyoma Uterus, corpus  
7q22 del(7)(q22q31)ordel(7)(q31q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 del(7)(q22q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 del(7)(q22q32) Acute myeloblastic leukemia with maturation (FAB type M2)   10   
7q22 del(7)(q22q32) Acute myeloblastic leukemia without maturation (FAB type M1)    
7q22 del(7)(q22q32) Acute myeloid leukemia, NOS   14   
7q22 del(7)(q22q32) Acute myelomonocytic leukemia (FAB type M4)    
7q22 del(7)(q22q32) Adenocarcinoma Lung  
7q22 del(7)(q22q32) Adult T-cell lymphoma/leukemia (HTLV-1+)    
7q22 del(7)(q22q32) Chronic lymphocytic leukemia   12   
7q22 del(7)(q22q32) Chronic myeloid leukemia, t(9;22)    
7q22 del(7)(q22q32) Chronic myeloproliferative disorder, NOS    
7q22 del(7)(q22q32) Diffuse large B-cell lymphoma    
7q22 del(7)(q22q32) Follicular lymphoma    
7q22 del(7)(q22q32) Hodgkin disease, NOS    
7q22 del(7)(q22q32) Idiopathic myelofibrosis    
7q22 del(7)(q22q32) Leiomyoma Uterus, corpus 42   
7q22 del(7)(q22q32) Mantle cell lymphoma    
7q22 del(7)(q22q32) Mature B-cell neoplasm, NOS    
7q22 del(7)(q22q32) Multiple myeloma    
7q22 del(7)(q22q32) Myelodysplastic syndrome, NOS    
7q22 del(7)(q22q32) Refractory anemia    
7q22 del(7)(q22q32) Refractory anemia with excess of blasts (FAB)    
7q22 del(7)(q22q32) Splenic marginal zone B-cell lymphoma    
7q22 del(7)(q22q32) Squamous cell carcinoma Tongue  
7q22 del(7)(q22q33) Splenic marginal zone B-cell lymphoma    
7q22 del(7)(q22q34) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 del(7)(q22q34) Acute myeloid leukemia, NOS   18   
7q22 del(7)(q22q34) Acute myelomonocytic leukemia (FAB type M4)    
7q22 del(7)(q22q34) Astrocytoma, grade III-IV/Glioblastoma Brain  
7q22 del(7)(q22q34) Chronic lymphocytic leukemia    
7q22 del(7)(q22q34) Chronic myeloid leukemia, t(9;22)    
7q22 del(7)(q22q34) Chronic myelomonocytic leukemia    
7q22 del(7)(q22q34) Diffuse large B-cell lymphoma    
7q22 del(7)(q22q34) Follicular lymphoma    
7q22 del(7)(q22q34) Myelodysplastic syndrome, NOS    
7q22 del(7)(q22q34) Polycythemia vera    
7q22 del(7)(q22q34) Refractory anemia    
7q22 del(7)(q22q34) Refractory anemia with excess of blasts (FAB)    
7q22 del(7)(q22q34) Refractory cytopenia with multilineage dysplasia    
7q22 del(7)(q22q34) Splenic marginal zone B-cell lymphoma    
7q22 del(7)(q22q34) Squamous cell carcinoma Oral cavity  
7q22 del(7)(q22q35) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 del(7)(q22q35) Acute myeloid leukemia, NOS    
7q22 del(7)(q22q36) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q22 del(7)(q22q36) Acute megakaryoblastic leukemia (FAB type M7)    
7q22 del(7)(q22q36) Acute monoblastic leukemia (FAB type M5)    
7q22 del(7)(q22q36) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q22 del(7)(q22q36) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q22 del(7)(q22q36) Acute myeloid leukemia, NOS   21   
7q22 del(7)(q22q36) Acute myelomonocytic leukemia (FAB type M4)    
7q22 del(7)(q22q36) Chronic lymphocytic leukemia    
7q22 del(7)(q22q36) Chronic myelomonocytic leukemia    
7q22 del(7)(q22q36) Diffuse large B-cell lymphoma    
7q22 del(7)(q22q36) Follicular lymphoma    
7q22 del(7)(q22q36) Leiomyoma Uterus, corpus  
7q22 del(7)(q22q36) Mature B-cell neoplasm, NOS    
7q22 del(7)(q22q36) Myelodysplastic syndrome, NOS   10   
7q22 del(7)(q22q36) Refractory anemia with excess of blasts (FAB)    
7q22 der(7)t(1;7)(q21;q22) Acute myeloid leukemia, NOS    
7q22 der(7)t(7;11)(q22;p13) Acute myeloblastic leukemia without maturation (FAB type M1)    
7q22 dup(7)(q11q22) Adult T-cell lymphoma/leukemia (HTLV-1+)    
7q22 dup(7)(q22q32) Adenocarcinoma Prostate