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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7q21 t(2;7)(p11;q21) Splenic marginal zone B-cell lymphoma   IGK/CDK6
7q21 t(2;7)(p12;q21) Chronic lymphocytic leukemia    
7q21 t(3;7)(q26;q21) Chronic myeloid leukemia, t(9;22)    
7q21 t(6;7)(p24;q21) Chronic myeloid leukemia, t(9;22)    
7q21 t(7;14)(q21;q32) Acute myeloid leukemia, NOS    
7q21 t(7;14)(q21;q32) Chronic lymphocytic leukemia   IGH/CDK6,IGH/ERVW-1
7q21 t(7;19)(q21;p13) Chronic myeloid leukemia, aberrant translocation    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7q21 add(7)(q21) Acute erythroleukemia (FAB type M6)    
7q21 add(7)(q21) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q21 add(7)(q21) Acute myeloid leukemia, NOS    
7q21 add(7)(q21) Chondromyxoid fibroma Skeleton  
7q21 add(7)(q21) Combined germ cell tumors Testis  
7q21 add(7)(q21) Diffuse large B-cell lymphoma    
7q21 add(7)(q21) Follicular lymphoma    
7q21 add(7)(q21) Refractory anemia with excess blasts-1    
7q21 add(7)(q21) Seminoma/Dysgerminoma Testis  
7q21 add(7)(q21) Splenic marginal zone B-cell lymphoma    
7q21 add(7)(q21) Squamous cell carcinoma Tongue  
7q21 add(7)(q21) Teratoma (mature and immature) Testis  
7q21 del(7)(q21) Acute erythroleukemia (FAB type M6)    
7q21 del(7)(q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q21 del(7)(q21) Acute monoblastic leukemia (FAB type M5)    
7q21 del(7)(q21) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q21 del(7)(q21) Acute myeloblastic leukemia without maturation (FAB type M1)    
7q21 del(7)(q21) Acute myeloid leukemia, NOS   16   
7q21 del(7)(q21) Acute myelomonocytic leukemia (FAB type M4)    
7q21 del(7)(q21) Adenocarcinoma Stomach  
7q21 del(7)(q21) Adenocarcinoma Kidney  
7q21 del(7)(q21) Adenocarcinoma Ovary  
7q21 del(7)(q21) Adenocarcinoma Breast  
7q21 del(7)(q21) Burkitt lymphoma/leukemia    
7q21 del(7)(q21) Carcinoma, NOS Oesophagus  
7q21 del(7)(q21) Chronic myeloid leukemia, t(9;22)    
7q21 del(7)(q21) Follicular lymphoma    
7q21 del(7)(q21) Mature B-cell neoplasm, NOS    
7q21 del(7)(q21) Myelodysplastic syndrome, NOS    
7q21 del(7)(q21) Refractory anemia with excess blasts-1    
7q21 del(7)(q21) Refractory anemia with excess blasts-2    
7q21 del(7)(q21) Refractory anemia with excess of blasts (FAB)    
7q21 del(7)(q21) Splenic marginal zone B-cell lymphoma    
7q21 del(7)(q21q22) Adenocarcinoma Lung  
7q21 del(7)(q21q22) Leiomyoma Uterus, corpus  
7q21 del(7)(q21q31) Acute erythroleukemia (FAB type M6)    
7q21 del(7)(q21q31) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q21 del(7)(q21q31) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q21 del(7)(q21q31) Acute myeloblastic leukemia without maturation (FAB type M1)    
7q21 del(7)(q21q31) Acute myeloid leukemia, NOS    
7q21 del(7)(q21q31) Acute myelomonocytic leukemia (FAB type M4)    
7q21 del(7)(q21q31) Chronic lymphocytic leukemia    
7q21 del(7)(q21q31) Chronic myelomonocytic leukemia    
7q21 del(7)(q21q31) Leiomyoma Uterus, corpus 35   
7q21 del(7)(q21q31) Multiple myeloma    
7q21 del(7)(q21q31) Polycythemia vera    
7q21 del(7)(q21q31) Refractory anemia with excess of blasts (FAB)    
7q21 del(7)(q21q31) Refractory anemia with ringed sideroblasts    
7q21 del(7)(q21q31) Splenic marginal zone B-cell lymphoma    
7q21 del(7)(q21q32) Acute monoblastic leukemia (FAB type M5)    
7q21 del(7)(q21q32) Leiomyoma Uterus, corpus  
7q21 del(7)(q21q33) Acute monoblastic leukemia (FAB type M5)    
7q21 del(7)(q21q33) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q21 del(7)(q21q33) Acute myeloblastic leukemia without maturation (FAB type M1)    
7q21 del(7)(q21q33) Acute myelomonocytic leukemia (FAB type M4)    
7q21 del(7)(q21q33) Chronic myeloid leukemia, t(9;22)    
7q21 del(7)(q21q33) Refractory anemia with excess of blasts (FAB)    
7q21 del(7)(q21q34) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q21 del(7)(q21q34) Refractory anemia with excess of blasts (FAB)    
7q21 del(7)(q21q35) Acute erythroleukemia (FAB type M6)    
7q21 del(7)(q21q35) Acute monoblastic leukemia (FAB type M5)    
7q21 del(7)(q21q35) Acute myeloid leukemia, NOS    
7q21 del(7)(q21q36) Acute myeloid leukemia, NOS    
7q21 del(7)(q21q36) Leiomyoma Uterus, corpus  
7q21 der(13)t(7;13)(q21;q34) Burkitt lymphoma/leukemia    
7q21 der(7)t(7;12)(q21;q13) Juvenile myelomonocytic leukemia    
7q21 dup(7)(q21q31) Angioimmunoblastic T-cell lymphoma