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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7q11 inv(7)(p22q11) Adenocarcinoma Breast  
7q11 inv(7)(p22q11) Squamous cell carcinoma Oro- and hypopharynx  
7q11 inv(7)(q11q32) Adenocarcinoma Breast  
7q11 t(1;7)(p11;q11) Meningioma Brain  
7q11 t(2;7)(q31;q11) Chronic myeloid leukemia, t(9;22)    
7q11 t(7;11)(q11;p15) Acute erythroleukemia (FAB type M6)    
7q11 t(7;11)(q11;q23) Multiple myeloma    
7q11 t(7;12)(q11;p13) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q11 t(7;17)(q11;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 t(7;9)(q11;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   PAX5/AUTS2,PAX5/ELN
7q11 t(7;9;22)(q11;q34;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 t(7;9;22)(q11;q34;q11) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7q11 add(7)(q11) Acute erythroleukemia (FAB type M6)    
7q11 add(7)(q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 add(7)(q11) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q11 add(7)(q11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q11 add(7)(q11) Acute myeloid leukemia, NOS   16   
7q11 add(7)(q11) Acute myelomonocytic leukemia (FAB type M4)    
7q11 add(7)(q11) Adenocarcinoma Ovary  
7q11 add(7)(q11) Adenocarcinoma Large intestine  
7q11 add(7)(q11) Adenocarcinoma Breast  
7q11 add(7)(q11) Astrocytoma, grade III-IV/Glioblastoma Brain  
7q11 add(7)(q11) Combined germ cell tumors Testis  
7q11 add(7)(q11) Diffuse large B-cell lymphoma    
7q11 add(7)(q11) Follicular lymphoma    
7q11 add(7)(q11) Leiomyosarcoma Soft tissue  
7q11 add(7)(q11) Mesothelioma Pleura  
7q11 add(7)(q11) Multiple myeloma    
7q11 add(7)(q11) Mycosis fungoides/Sezary syndrome    
7q11 add(7)(q11) Myelodysplastic syndrome, NOS    
7q11 add(7)(q11) Refractory cytopenia with multilineage dysplasia    
7q11 add(7)(q11) Squamous cell carcinoma Lung  
7q11 add(7)(q11) Squamous cell carcinoma Larynx  
7q11 add(7)(q11) Squamous cell carcinoma Tongue  
7q11 add(7)(q11) Squamous cell carcinoma Oro- and hypopharynx  
7q11 add(7)(q11) Squamous cell carcinoma Oral cavity  
7q11 add(7)(q11) Teratoma (mature and immature) Testis  
7q11 add(7)(q11) Undifferentiated pleomorphic sarcoma Soft tissue  
7q11 del(7)(q11) Acute erythroleukemia (FAB type M6)    
7q11 del(7)(q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma   13   
7q11 del(7)(q11) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q11 del(7)(q11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q11 del(7)(q11) Acute myeloblastic leukemia without maturation (FAB type M1)    
7q11 del(7)(q11) Acute myeloid leukemia, NOS   24   
7q11 del(7)(q11) Acute myelomonocytic leukemia (FAB type M4)    
7q11 del(7)(q11) Adenocarcinoma Breast  
7q11 del(7)(q11) Adenocarcinoma Ovary  
7q11 del(7)(q11) Adenocarcinoma Large intestine  
7q11 del(7)(q11) Adenocarcinoma Pancreas  
7q11 del(7)(q11) Adenocarcinoma Kidney  
7q11 del(7)(q11) Astrocytoma, grade III-IV/Glioblastoma Brain  
7q11 del(7)(q11) Chronic lymphocytic leukemia    
7q11 del(7)(q11) Chronic myeloid leukemia, t(9;22)    
7q11 del(7)(q11) Diffuse large B-cell lymphoma    
7q11 del(7)(q11) Leiomyoma Uterus, corpus  
7q11 del(7)(q11) Leiomyosarcoma Soft tissue  
7q11 del(7)(q11) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
7q11 del(7)(q11) Mantle cell lymphoma    
7q11 del(7)(q11) Meningioma Brain  
7q11 del(7)(q11) Multiple myeloma    
7q11 del(7)(q11) Myelodysplastic syndrome, NOS    
7q11 del(7)(q11) Myelodysplastic/myeloproliferative disease, NOS    
7q11 del(7)(q11) Osteosarcoma, NOS Skeleton  
7q11 del(7)(q11) Refractory anemia    
7q11 del(7)(q11) Refractory anemia with excess of blasts (FAB)    
7q11 del(7)(q11) Refractory cytopenia with multilineage dysplasia    
7q11 del(7)(q11) Squamous cell carcinoma Lung  
7q11 del(7)(q11) Teratoma (mature and immature) Testis  
7q11 del(7)(q11) Undifferentiated carcinoma, large cell Lung  
7q11 del(7)(q11q22) Acute erythroleukemia (FAB type M6)    
7q11 del(7)(q11q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 del(7)(q11q22) Acute myeloid leukemia, NOS    
7q11 del(7)(q11q22) Follicular lymphoma    
7q11 del(7)(q11q22) Refractory anemia with excess of blasts (FAB)    
7q11 del(7)(q11q22) Squamous cell carcinoma Lung  
7q11 del(7)(q11q32) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q11 del(7)(q11q32) Acute myeloid leukemia, NOS    
7q11 del(7)(q11q32) Follicular lymphoma    
7q11 del(7)(q11q32) Leiomyoma Uterus, corpus  
7q11 del(7)(q11q33) Acute myeloid leukemia, NOS    
7q11 del(7)(q11q34) Acute myeloid leukemia, NOS    
7q11 del(7)(q11q36) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 del(7)(q11q36) Acute myeloid leukemia, NOS    
7q11 del(7)(q22q31)ordel(7)(q11q22) Leiomyoma Uterus, corpus  
7q11 der(1)t(1;7)(p32;q11) Neuroblastoma Adrenal  
7q11 der(11)t(7;11)(q11;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 der(12)t(7;12)(q11;p12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 der(12)t(7;12)(q11;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 der(12)t(7;12)(q11;q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 der(13)t(7;13)(q11;q12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 der(16)t(7;16)(q11;q24) Adult T-cell lymphoma/leukemia (HTLV-1+)    
7q11 der(19)t(7;19)(q11;q13) Adenocarcinoma Breast  
7q11 der(19)t(7;19)(q11;q13) Multiple myeloma    
7q11 der(21)t(7;21)(q11;p11) Multiple myeloma    
7q11 der(22)t(7;22)(q11;p11) Acute erythroleukemia (FAB type M6)    
7q11 der(7)del(7)(p11)del(7)(q11) Refractory cytopenia with multilineage dysplasia    
7q11 der(7)t(7;11)(q11;q13) Acute myeloid leukemia, NOS    
7q11 der(7)t(7;22)(q11;q11) Acute myeloid leukemia, NOS    
7q11 der(7)t(7;7)(p21;q11) Multiple myeloma    
7q11 der(9)t(7;9)(q11;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 der(9)t(7;9)(q11;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7q11 dic(1;7)(p11;q11) Myelodysplastic syndrome, NOS    
7q11 dic(1;7)(p11;q11) Refractory anemia    
7q11 dic(1;7)(p11;q11) Refractory anemia with excess of blasts (FAB)    
7q11 dic(7;11)(q11;p11) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7q11 dic(7;16)(q11;p11) Refractory anemia with excess of blasts (FAB)    
7q11 dic(7;22)(q11;q10) Acute myeloblastic leukemia without maturation (FAB type M1)    
7q11 dup(7)(q11q22) Adult T-cell lymphoma/leukemia (HTLV-1+)    
7q11 dup(7)(q11q32) Diffuse large B-cell lymphoma    
7q11 dup(7)(q11q32) Follicular lymphoma    
7q11 dup(7)(q11q35) Angioimmunoblastic T-cell lymphoma    
7q11 idic(7)(q11) Acute myeloblastic leukemia with maturation (FAB type M2)    
7q11 r(7)(p22q11) Acute megakaryoblastic leukemia (FAB type M7)