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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7p22 inv(7)(p15p22) Multiple myeloma    
7p22 inv(7)(p22q11) Adenocarcinoma Breast  
7p22 inv(7)(p22q11) Squamous cell carcinoma Oro- and hypopharynx  
7p22 inv(7)(p22q32) Chronic lymphocytic leukemia    
7p22 inv(7)(p22q32) Leiomyoma Uterus, corpus  
7p22 t(2;7)(p12;p22) Acute megakaryoblastic leukemia (FAB type M7)    
7p22 t(7;12)(p22;q13) Pericytoma Tongue ACTB/GLI1
7p22 t(7;13)(p22;q14) Chronic lymphocytic leukemia    
7p22 t(7;14)(p22;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p22 t(7;21)(p22;q22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)   RUNX1/USP42
7p22 t(7;21)(p22;q22) Acute myelomonocytic leukemia (FAB type M4)   RUNX1/USP42
7p22 t(7;22)(p22;q11) Chronic myeloid leukemia, aberrant translocation    
7p22 t(7;22)(p22;q12) Ewing sarcoma Skeleton  
7p22 t(7;7)(p22;q22) Chronic myeloid leukemia, aberrant translocation    
7p22 t(7;8)(p22;q11) Lipoblastoma Soft tissue  
7p22 t(7;9;22)(p22;q34;q11) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7p22 add(7)(p22) Acute lymphoblastic leukemia/lymphoblastic lymphoma   27   
7p22 add(7)(p22) Acute megakaryoblastic leukemia (FAB type M7)    
7p22 add(7)(p22) Acute monoblastic leukemia (FAB type M5)    
7p22 add(7)(p22) Acute myeloblastic leukemia with maturation (FAB type M2)    
7p22 add(7)(p22) Acute myeloblastic leukemia with minimal differentiation (FAB type M0)    
7p22 add(7)(p22) Acute myeloblastic leukemia without maturation (FAB type M1)    
7p22 add(7)(p22) Acute myeloid leukemia, NOS    
7p22 add(7)(p22) Adenocarcinoma Oesophagus  
7p22 add(7)(p22) Adenocarcinoma Ovary 11   
7p22 add(7)(p22) Adenocarcinoma Breast 14   
7p22 add(7)(p22) Adenocarcinoma Large intestine  
7p22 add(7)(p22) Adenocarcinoma Pancreas  
7p22 add(7)(p22) Adenocarcinoma Stomach  
7p22 add(7)(p22) Adenocarcinoma Lung  
7p22 add(7)(p22) Adenoma Pituitary  
7p22 add(7)(p22) Adult T-cell lymphoma/leukemia (HTLV-1+)    
7p22 add(7)(p22) Astrocytoma, grade III-IV/Glioblastoma Brain  
7p22 add(7)(p22) Atypical lipomatous tumor/atypical lipoma/well-differentiated liposarcoma Soft tissue  
7p22 add(7)(p22) B-prolymphocytic leukemia    
7p22 add(7)(p22) Burkitt lymphoma/leukemia    
7p22 add(7)(p22) Chondrosarcoma, NOS Skeleton  
7p22 add(7)(p22) Chronic lymphocytic leukemia    
7p22 add(7)(p22) Chronic myeloid leukemia, t(9;22)    
7p22 add(7)(p22) Diffuse large B-cell lymphoma   16   
7p22 add(7)(p22) Follicular lymphoma    
7p22 add(7)(p22) Hodgkin disease, nodular sclerosis    
7p22 add(7)(p22) Leiomyosarcoma Soft tissue  
7p22 add(7)(p22) Liposarcoma, dedifferentiated Intraabdominal  
7p22 add(7)(p22) Liposarcoma, pleomorphic Soft tissue  
7p22 add(7)(p22) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
7p22 add(7)(p22) Mantle cell lymphoma    
7p22 add(7)(p22) Mature B-cell neoplasm, NOS    
7p22 add(7)(p22) Mature T- and NK-cell neoplasm, NOS    
7p22 add(7)(p22) Multiple myeloma   28   
7p22 add(7)(p22) Mycosis fungoides/Sezary syndrome    
7p22 add(7)(p22) Myelodysplastic syndrome, NOS    
7p22 add(7)(p22) Myxofibrosarcoma Soft tissue  
7p22 add(7)(p22) Osteosarcoma, NOS Skeleton  
7p22 add(7)(p22) Plasma cell leukemia    
7p22 add(7)(p22) Squamous cell carcinoma Larynx  
7p22 add(7)(p22) Synovial sarcoma Soft tissue  
7p22 add(7)(p22) T-cell granular lymphocytic leukemia    
7p22 add(7)(p22) Teratoma (mature and immature) Testis  
7p22 add(7)(p22) Undifferentiated pleomorphic sarcoma Soft tissue  
7p22 add(7)(p22) Wilms tumor Kidney  
7p22 del(7)(p13p22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p22 del(7)(p15p22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p22 der(7)t(1;7)(q12;p22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p22 der(7)t(1;7)(q12;p22) Multiple myeloma    
7p22 der(7)t(3;7)(q21;p22) Adenocarcinoma Kidney  
7p22 der(7)t(6;7)(p21;p22) Acute myeloid leukemia, NOS    
7p22 der(7;11)ins(7;11)(p14;p11q25)t(7;11)(p22;p11) Chronic myeloid leukemia, t(9;22)    
7p22 dic(5;7)(q13;p22) Acute megakaryoblastic leukemia (FAB type M7)    
7p22 dup(7)(p15p22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p22 dup(7)(p15p22) Adenocarcinoma Lung  
7p22 r(7)(p22q11) Acute megakaryoblastic leukemia (FAB type M7)    
7p22 r(7)(p22q36) Acute lymphoblastic leukemia/lymphoblastic lymphoma