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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7p15 inv(7)(p15p22) Multiple myeloma    
7p15 inv(7)(p15q22) Chronic myeloid leukemia, t(9;22)    
7p15 inv(7)(p15q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p15 inv(7)(p15q34) Acute lymphoblastic leukemia/lymphoblastic lymphoma   18  TRB/HOXA10,TRB/HOXA11
7p15 inv(7)(p15q34) Adenocarcinoma Kidney  
7p15 inv(7)(p15q34)ort(7;7)(p15;q34) Acute lymphoblastic leukemia/lymphoblastic lymphoma   TRB/HOXA10,TRB/HOXA11
7p15 inv(7)(p15q34)ort(7;7)(p15;q34) Acute lymphoblastic leukemia/lymphoblastic lymphoma   TRB/HOXA10,TRB/HOXA11
7p15 t(7;11)(p15;p15) Acute monoblastic leukemia with differentiation (FAB type M5b)    
7p15 t(7;11)(p15;p15) Acute myeloblastic leukemia with maturation (FAB type M2)   40  NUP98/HOXA11,NUP98/HOXA13,NUP98/HOXA9
7p15 t(7;11)(p15;p15) Acute myeloid leukemia, NOS   NUP98/HOXA9
7p15 t(7;11)(p15;p15) Acute myelomonocytic leukemia (FAB type M4)   15  NUP98/HOXA9
7p15 t(7;11)(p15;p15) Chronic myeloid leukemia, t(9;22)   NUP98/HOXA11,NUP98/HOXA9
7p15 t(7;11)(p15;p15) Chronic myelomonocytic leukemia   NUP98/HOXA9
7p15 t(7;11)(p15;p15) Chronic myeloproliferative disorder, NOS    
7p15 t(7;11)(p15;q13) Follicular lymphoma    
7p15 t(7;12)(p15;p13) Acute myeloid leukemia, NOS   ETV6+
7p15 t(7;14)(p15;q11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p15 t(7;14)(p15;q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p15 t(7;17)(p15;q11) Endometrial stromal sarcoma Uterus, corpus JAZF1/SUZ12
7p15 t(7;17)(p15;q21) Endometrial stromal sarcoma Uterus, corpus  
7p15 t(7;7)(p15;q34) Acute lymphoblastic leukemia/lymphoblastic lymphoma   12  HOXA10/TRB,TRB/HOXA10,TRB/HOXA9
7p15 t(7;9;22)(p15;q34;q11) Chronic myeloid leukemia, aberrant translocation    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
7p15 add(7)(p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma   12   
7p15 add(7)(p15) Acute myeloblastic leukemia with maturation (FAB type M2)    
7p15 add(7)(p15) Acute myeloid leukemia, NOS    
7p15 add(7)(p15) Adenocarcinoma Lung  
7p15 add(7)(p15) Adenocarcinoma Ovary  
7p15 add(7)(p15) Adenocarcinoma Large intestine  
7p15 add(7)(p15) Astrocytoma, grade III-IV/Glioblastoma Brain  
7p15 add(7)(p15) Diffuse large B-cell lymphoma    
7p15 add(7)(p15) Mature B-cell neoplasm, NOS    
7p15 add(7)(p15) Multiple myeloma   12   
7p15 del(7)(p11p15) Acute myeloid leukemia, NOS    
7p15 del(7)(p11p15) Chronic myeloid leukemia, t(9;22)    
7p15 del(7)(p12p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p15 del(7)(p13p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p15 del(7)(p13p15) Chordoma Skeleton  
7p15 del(7)(p13p15) Diffuse large B-cell lymphoma    
7p15 del(7)(p14p15) Chronic myeloid leukemia, t(9;22)    
7p15 del(7)(p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma   27   
7p15 del(7)(p15) Acute megakaryoblastic leukemia (FAB type M7)    
7p15 del(7)(p15) Acute monoblastic leukemia (FAB type M5)    
7p15 del(7)(p15) Acute myeloid leukemia, NOS    
7p15 del(7)(p15) Adenocarcinoma Large intestine  
7p15 del(7)(p15) Adenocarcinoma Breast  
7p15 del(7)(p15) Adenocarcinoma Ovary  
7p15 del(7)(p15) Adult T-cell lymphoma/leukemia (HTLV-1+)    
7p15 del(7)(p15) Astrocytoma, grade III-IV/Glioblastoma Brain  
7p15 del(7)(p15) Chronic myeloid leukemia, t(9;22)    
7p15 del(7)(p15) Diffuse large B-cell lymphoma    
7p15 del(7)(p15) Idiopathic myelofibrosis    
7p15 del(7)(p15) Mature B-cell neoplasm, NOS    
7p15 del(7)(p15) Multiple myeloma    
7p15 del(7)(p15) Osteosarcoma, NOS Skeleton  
7p15 del(7)(p15) T-prolymphocytic leukemia    
7p15 del(7)(p15) Undifferentiated pleomorphic sarcoma Soft tissue  
7p15 del(7)(p15p21) Acute myeloblastic leukemia with maturation (FAB type M2)    
7p15 del(7)(p15p22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p15 der(7)add(7)(p15)add(7)(q36) Adenocarcinoma Ovary  
7p15 der(7)del(7)(p15)del(7)(q32) Adenocarcinoma Liver  
7p15 dup(7)(p15p22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
7p15 dup(7)(p15p22) Adenocarcinoma Lung