Skip Navigation
NCI banner National Cancer Institute U.S. National Institutes of Health National Cancer Institute
Chromosomes
  • Tools
  • Genetic and Physical SNP Maps
  • SNP500Cancer
Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

Expand Gene List:




[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q42 inv(1)(p13q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q42 inv(1)(q21q42) Leiomyoma Uterus, corpus  
1q42 t(1;14)(q42;q32) Follicular lymphoma    
1q42 t(1;7)(q42;q22) Leiomyoma Uterus, corpus  
1q42 t(1;9;22)(q42;q34;q11) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q42 add(1)(q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q42 add(1)(q42) Acute myeloid leukemia, NOS    
1q42 add(1)(q42) Adenocarcinoma Breast  
1q42 add(1)(q42) Adenocarcinoma Lung  
1q42 add(1)(q42) Adenocarcinoma Ovary  
1q42 add(1)(q42) Adenocarcinoma Kidney  
1q42 add(1)(q42) Adult T-cell lymphoma/leukemia (HTLV-1+)    
1q42 add(1)(q42) Diffuse large B-cell lymphoma    
1q42 add(1)(q42) Follicular lymphoma    
1q42 add(1)(q42) Liposarcoma, dedifferentiated Intraabdominal  
1q42 add(1)(q42) Mature T- and NK-cell neoplasm, NOS    
1q42 add(1)(q42) Multiple myeloma    
1q42 add(1)(q42) Neuroblastoma Adrenal  
1q42 add(1)(q42) Ossifying fibromyxoid tumor Soft tissue  
1q42 add(1)(q42) Squamous cell carcinoma Oral cavity  
1q42 del(1)(q21q42) Multiple myeloma    
1q42 del(1)(q32q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q42 del(1)(q32q42) Diffuse large B-cell lymphoma    
1q42 del(1)(q32q42) Hodgkin disease, nodular sclerosis    
1q42 del(1)(q32q42) Leiomyoma Uterus, corpus  
1q42 del(1)(q32q42) Multiple myeloma    
1q42 del(1)(q32q42) Myelodysplastic syndrome, NOS    
1q42 del(1)(q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma   13   
1q42 del(1)(q42) Acute myeloid leukemia, NOS    
1q42 del(1)(q42) Adenocarcinoma Ovary  
1q42 del(1)(q42) Adenocarcinoma Breast 16   
1q42 del(1)(q42) Astrocytoma, grade III-IV/Glioblastoma Brain  
1q42 del(1)(q42) Chronic lymphocytic leukemia    
1q42 del(1)(q42) Diffuse large B-cell lymphoma   10  ESRRG/ACBD3
1q42 del(1)(q42) Follicular lymphoma    
1q42 del(1)(q42) Hairy cell leukemia    
1q42 del(1)(q42) Leiomyoma Uterus, corpus  
1q42 del(1)(q42) Leiomyosarcoma Soft tissue  
1q42 del(1)(q42) Malignant melanoma Skin  
1q42 del(1)(q42) Mature B-cell neoplasm, NOS    
1q42 del(1)(q42) Mature T- and NK-cell neoplasm, NOS    
1q42 del(1)(q42) Mesothelioma Pleura  
1q42 del(1)(q42) Multiple myeloma    
1q42 del(1)(q42) Myxofibrosarcoma Soft tissue  
1q42 del(1)(q42) Osteosarcoma, NOS Skeleton  
1q42 del(1)(q42) Teratoma (mature and immature) Testis  
1q42 del(1)(q42q44) Diffuse large B-cell lymphoma    
1q42 der(1)trp(1)(q11q32)dup(1)(q41q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q42 dup(1)(q12q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q42 dup(1)(q12q42) Diffuse large B-cell lymphoma    
1q42 dup(1)(q12q42) Multiple myeloma    
1q42 dup(1)(q21q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma   12   
1q42 dup(1)(q21q42) Acute myeloid leukemia, NOS    
1q42 dup(1)(q21q42) Adult T-cell lymphoma/leukemia (HTLV-1+)    
1q42 dup(1)(q21q42) Burkitt lymphoma/leukemia    
1q42 dup(1)(q21q42) Follicular lymphoma    
1q42 dup(1)(q21q42) Idiopathic myelofibrosis    
1q42 dup(1)(q21q42) Polycythemia vera    
1q42 dup(1)(q21q42) Refractory anemia    
1q42 dup(1)(q23q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q42 dup(1)(q23q42) Follicular lymphoma    
1q42 dup(1)(q41q42) Diffuse large B-cell lymphoma    
1q42 ider(1)(q10)del(1)(q42) Multiple myeloma