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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q25 t(1;1)(p36;q25) Diffuse large B-cell lymphoma    
1q25 t(1;12)(q25;p12) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q25 t(1;14)(q25;q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma   IGH/LHX4
1q25 t(1;2)(q25;p23) Anaplastic large cell lymphoma, systemic type    
1q25 t(1;3)(q25;q27) Diffuse large B-cell lymphoma   GAS5/BCL6
1q25 t(1;8)(q25;p11) Chronic myeloproliferative disorder, NOS    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q25 add(1)(q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q25 add(1)(q25) Adenocarcinoma Ovary  
1q25 add(1)(q25) Adenocarcinoma Breast  
1q25 del(1)(q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q25 del(1)(q25) Adenocarcinoma Ovary  
1q25 del(1)(q25) Adenocarcinoma Breast  
1q25 del(1)(q25) Astrocytoma, grade III-IV/Glioblastoma Brain  
1q25 del(1)(q25) Burkitt lymphoma/leukemia    
1q25 del(1)(q25) Diffuse large B-cell lymphoma   RABGAP1L/ZBTB37
1q25 del(1)(q25) Mature B-cell neoplasm, NOS    
1q25 del(1)(q25) Multiple myeloma    
1q25 der(1)t(1;1)(p13;q25) Squamous cell carcinoma Oral cavity  
1q25 der(14)t(1;14)(q25;q32) Burkitt lymphoma/leukemia    
1q25 der(16)t(1;16)(q25;q23) Acute myeloid leukemia, NOS    
1q25 der(16)t(1;16)(q25;q24) Multiple myeloma    
1q25 der(20)t(1;20)(q25;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q25 der(21)t(1;21)(q25;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q25 der(21)t(1;21)(q25;q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q25 der(3)t(1;3)(q25;q25) Adenocarcinoma Ovary  
1q25 der(4)t(1;4)(q25;q32) Hepatoblastoma Liver  
1q25 der(X)t(X;1)(q28;q25) Acute megakaryoblastic leukemia (FAB type M7)    
1q25 dup(1)(q11q25) Multiple myeloma    
1q25 dup(1)(q12q25) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q25 dup(1)(q12q25) Burkitt lymphoma/leukemia    
1q25 dup(1)(q12q25) Follicular lymphoma    
1q25 dup(1)(q12q25) Mature B-cell neoplasm, NOS    
1q25 dup(1)(q12q25) Multiple myeloma    
1q25 dup(1)(q21q25) Burkitt lymphoma/leukemia    
1q25 dup(1)(q21q25) Diffuse large B-cell lymphoma    
1q25 dup(1)(q21q25) Follicular lymphoma    
1q25 dup(1)(q25q32) Burkitt lymphoma/leukemia    
1q25 dup(1)(q25q32) Follicular lymphoma    
1q25 dup(1)(q25q44) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q25 dup(1)(q25q44) Chronic lymphocytic leukemia    
1q25 dup(1)(q25q44) Diffuse large B-cell lymphoma    
1q25 dup(1)(q25q44) Follicular lymphoma    
1q25 dup(1)(q25q44) Mantle cell lymphoma    
1q25 dup(1)(q25q44) Mature B-cell neoplasm, NOS    
1q25 dup(1)(q25q44) Peripheral T-cell lymphoma, unspecified