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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q23 t(1;11)(q23;p15) Acute myeloblastic leukemia with maturation (FAB type M2)    
1q23 t(1;13)(q23;q14) Chronic lymphocytic leukemia    
1q23 t(1;14)(q23;q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 t(1;16)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 t(1;19)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   175  TCF3/PBX1,TCF3+
1q23 t(1;19)(q23;p13) Burkitt lymphoma/leukemia   TCF3/PBX1
1q23 t(1;19)(q23;p13) Follicular lymphoma    
1q23 t(1;19)(q23;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 t(1;20)(q23;q13) Adenocarcinoma Breast PARD6B/CD48,UAP1/TSHZ2
1q23 t(1;22)(q23;q12) Myoepithelioma/myoepithelial carcinoma/mixed tumor Soft tissue EWSR1/PBX1
1q23 t(1;5)(q23;q33) Chronic myeloproliferative disorder, NOS    
1q23 t(1;9)(q23;q34) Acute lymphoblastic leukemia/lymphoblastic lymphoma    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q23 add(1)(q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 add(1)(q23) Adenocarcinoma Breast  
1q23 add(1)(q23) Adult T-cell lymphoma/leukemia (HTLV-1+)    
1q23 add(1)(q23) Diffuse large B-cell lymphoma    
1q23 add(1)(q23) Mesothelioma Pleura  
1q23 add(1)(q23) Undifferentiated pleomorphic sarcoma Soft tissue  
1q23 del(1)(q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 del(1)(q23) Acute monoblastic leukemia (FAB type M5)    
1q23 del(1)(q23) Adenocarcinoma Ovary  
1q23 del(1)(q23) Adenocarcinoma Lung  
1q23 del(1)(q23) Adenocarcinoma Breast  
1q23 del(1)(q23) Diffuse large B-cell lymphoma    
1q23 del(1)(q23) Follicular lymphoma    
1q23 del(1)(q23) Mature B-cell neoplasm, NOS    
1q23 del(1)(q23) Mesothelioma Pleura  
1q23 del(1)(q23) Multiple myeloma    
1q23 der(1)t(1;1)(p36;q23) Follicular lymphoma    
1q23 der(1)t(1;1)(p36;q23) Mature B-cell neoplasm, NOS    
1q23 der(13)t(1;13)(q23;q34) Burkitt lymphoma/leukemia    
1q23 der(14)t(1;14)(q23;q32) Diffuse large B-cell lymphoma    
1q23 der(15)t(1;15)(q23;q26) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 der(19)t(1;19)(q23;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   271   
1q23 der(19)t(1;19)(q23;p13) Bilineage or biphenotypic leukemia    
1q23 der(19)t(1;19)(q23;p13) Burkitt lymphoma/leukemia    
1q23 der(19)t(1;19)(q23;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 der(2)t(1;2)(q23;q35) Acute megakaryoblastic leukemia (FAB type M7)    
1q23 der(2)t(1;2)(q23;q35) Acute monoblastic leukemia (FAB type M5)    
1q23 der(22)t(1;22)(q23;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 dup(1)(q12q23) Follicular lymphoma    
1q23 dup(1)(q21q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 dup(1)(q21q23) Follicular lymphoma    
1q23 dup(1)(q21q23) Mature B-cell neoplasm, NOS    
1q23 dup(1)(q23q31) Diffuse large B-cell lymphoma    
1q23 dup(1)(q23q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 dup(1)(q23q32) Burkitt lymphoma/leukemia    
1q23 dup(1)(q23q32) Chronic myeloid leukemia, t(9;22)    
1q23 dup(1)(q23q32) Mature B-cell neoplasm, NOS    
1q23 dup(1)(q23q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 dup(1)(q23q42) Follicular lymphoma    
1q23 dup(1)(q23q44) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q23 dup(1)(q23q44) Burkitt lymphoma/leukemia    
1q23 dup(1)(q23q44) Multiple myeloma