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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q21 inv(1)(p22q21) Diffuse large B-cell lymphoma    
1q21 inv(1)(p36q21) Acute myeloblastic leukemia with maturation (FAB type M2)    
1q21 inv(1)(p36q21) Adenocarcinoma Kidney  
1q21 inv(1)(p36q21) Chronic myeloid leukemia, t(9;22)    
1q21 inv(1)(p36q21) Multiple myeloma    
1q21 inv(1)(q21q32) Acute myeloid leukemia, NOS    
1q21 inv(1)(q21q42) Leiomyoma Uterus, corpus  
1q21 t(1;1)(p32;q21) Follicular lymphoma    
1q21 t(1;10)(q21;p14) Chronic lymphocytic leukemia    
1q21 t(1;10)(q21;q24) Chronic lymphocytic leukemia    
1q21 t(1;11)(q21;q23) Acute monoblastic leukemia (FAB type M5)   KMT2A/MLLT11
1q21 t(1;11)(q21;q23) Acute monoblastic leukemia with differentiation (FAB type M5b)   KMT2A+
1q21 t(1;11)(q21;q23) Acute myeloblastic leukemia with maturation (FAB type M2)    
1q21 t(1;11)(q21;q23) Acute myeloblastic leukemia without maturation (FAB type M1)   KMT2A/MLLT11
1q21 t(1;11)(q21;q23) Acute myeloid leukemia, NOS   KMT2A/MLLT11,KMT2A+
1q21 t(1;11)(q21;q23) Acute myelomonocytic leukemia (FAB type M4)   13  KMT2A/MLLT11,KMT2A+
1q21 t(1;12)(q21;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   ETV6/ARNT
1q21 t(1;12)(q21;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 t(1;14)(q21;q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma   IGH/BCL9,IGH+
1q21 t(1;14)(q21;q32) Diffuse large B-cell lymphoma    
1q21 t(1;14)(q21;q32) Follicular lymphoma   IGH/FCGR2B
1q21 t(1;14)(q21;q32) Malignant melanoma Skin  
1q21 t(1;14)(q21;q32) Mature B-cell neoplasm, NOS   IGH+
1q21 t(1;16)(q21;q12) Multiple myeloma    
1q21 t(1;16)(q21;q13) Adenocarcinoma Breast  
1q21 t(1;16)(q21;q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 t(1;19)(q21;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 t(1;19)(q21;p13) Meningioma Brain  
1q21 t(1;19)(q21;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 t(1;2)(q21;q37) Acute myeloid leukemia, NOS   HRNR+
1q21 t(1;21)(q21;q22) Chronic myeloid leukemia, t(9;22)    
1q21 t(1;22)(q21;q11) Follicular lymphoma   IGL/BCL9
1q21 t(1;22)(q21;q11) Mature B-cell neoplasm, NOS    
1q21 t(1;9;22)(q21;q34;q11) Chronic myeloid leukemia, aberrant translocation   10  BCR/ABL1
1q21 t(X;1)(p11;q21) Adenocarcinoma Kidney 30   
1q21 t(X;1)(p22;q21) Burkitt lymphoma/leukemia    

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1q21 add(1)(q21) Acute erythroleukemia (FAB type M6)    
1q21 add(1)(q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 add(1)(q21) Acute myeloid leukemia, NOS    
1q21 add(1)(q21) Acute promyelocytic leukemia (FAB type M3)    
1q21 add(1)(q21) Adenocarcinoma Large intestine  
1q21 add(1)(q21) Adenocarcinoma Lung  
1q21 add(1)(q21) Adenocarcinoma Pancreas  
1q21 add(1)(q21) Adenocarcinoma Liver  
1q21 add(1)(q21) Adenocarcinoma Kidney  
1q21 add(1)(q21) Adenocarcinoma Breast  
1q21 add(1)(q21) Adenocarcinoma Ovary  
1q21 add(1)(q21) Adult T-cell lymphoma/leukemia (HTLV-1+)    
1q21 add(1)(q21) Astrocytoma, grade III-IV/Glioblastoma Brain  
1q21 add(1)(q21) Burkitt lymphoma/leukemia    
1q21 add(1)(q21) Chronic lymphocytic leukemia    
1q21 add(1)(q21) Combined germ cell tumors Testis  
1q21 add(1)(q21) Diffuse large B-cell lymphoma    
1q21 add(1)(q21) Follicular lymphoma    
1q21 add(1)(q21) Leiomyosarcoma Soft tissue  
1q21 add(1)(q21) Liposarcoma, dedifferentiated Intraabdominal  
1q21 add(1)(q21) Liposarcoma, dedifferentiated Soft tissue  
1q21 add(1)(q21) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
1q21 add(1)(q21) Mantle cell lymphoma    
1q21 add(1)(q21) Mature B-cell neoplasm, NOS    
1q21 add(1)(q21) Mature T- and NK-cell neoplasm, NOS    
1q21 add(1)(q21) Mesothelioma Pleura  
1q21 add(1)(q21) Multiple myeloma   14   
1q21 add(1)(q21) Myxofibrosarcoma Soft tissue  
1q21 add(1)(q21) Neuroblastoma Adrenal  
1q21 add(1)(q21) Nonneoplastic hematologic disorder/lesion    
1q21 add(1)(q21) Osteosarcoma, NOS Skeleton  
1q21 add(1)(q21) Refractory anemia with excess of blasts (FAB)    
1q21 add(1)(q21) Seminoma/Dysgerminoma Testis  
1q21 add(1)(q21) Squamous cell carcinoma Oral cavity  
1q21 add(1)(q21) Squamous cell carcinoma Tongue  
1q21 add(1)(q21) T-prolymphocytic leukemia    
1q21 add(1)(q21) Teratoma (mature and immature) Testis  
1q21 add(1)(q21) Undifferentiated pleomorphic sarcoma Soft tissue  
1q21 del(1)(q21) Acute erythroleukemia (FAB type M6)    
1q21 del(1)(q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 del(1)(q21) Acute monoblastic leukemia with differentiation (FAB type M5b)    
1q21 del(1)(q21) Acute myeloblastic leukemia with maturation (FAB type M2)    
1q21 del(1)(q21) Acute myeloid leukemia, NOS    
1q21 del(1)(q21) Acute myelomonocytic leukemia (FAB type M4)    
1q21 del(1)(q21) Acute promyelocytic leukemia (FAB type M3)    
1q21 del(1)(q21) Adenocarcinoma Breast  
1q21 del(1)(q21) Adenocarcinoma Lung  
1q21 del(1)(q21) Adenocarcinoma Pancreas  
1q21 del(1)(q21) Adenocarcinoma Large intestine  
1q21 del(1)(q21) Adenocarcinoma Kidney  
1q21 del(1)(q21) Adenocarcinoma Ovary 16   
1q21 del(1)(q21) Astrocytoma, grade III-IV/Glioblastoma Brain  
1q21 del(1)(q21) Burkitt lymphoma/leukemia    
1q21 del(1)(q21) Carcinoma, NOS Breast  
1q21 del(1)(q21) Chronic lymphocytic leukemia    
1q21 del(1)(q21) Chronic myeloid leukemia, aberrant translocation    
1q21 del(1)(q21) Chronic myeloid leukemia, t(9;22)    
1q21 del(1)(q21) Diffuse large B-cell lymphoma    
1q21 del(1)(q21) Ewing sarcoma Skeleton  
1q21 del(1)(q21) Follicular lymphoma    
1q21 del(1)(q21) Idiopathic myelofibrosis    
1q21 del(1)(q21) Liposarcoma, pleomorphic Soft tissue  
1q21 del(1)(q21) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
1q21 del(1)(q21) Mantle cell lymphoma    
1q21 del(1)(q21) Mature B-cell neoplasm, NOS    
1q21 del(1)(q21) Mesothelioma Pleura  
1q21 del(1)(q21) Multiple myeloma   11   
1q21 del(1)(q21) Myelodysplastic syndrome, NOS    
1q21 del(1)(q21) Myxofibrosarcoma Soft tissue  
1q21 del(1)(q21) Neuroblastoma Adrenal  
1q21 del(1)(q21) Osteosarcoma, NOS Skeleton  
1q21 del(1)(q21) Plasma cell leukemia    
1q21 del(1)(q21) Transitional cell carcinoma Bladder  
1q21 del(1)(q21) Undifferentiated carcinoma, small cell Lung  
1q21 del(1)(q21) Undifferentiated pleomorphic sarcoma Soft tissue  
1q21 del(1)(q21q42) Multiple myeloma    
1q21 der(1)del(1)(p31)del(1)(q21) Adenocarcinoma Ovary  
1q21 der(1)t(1;1)(p36;q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(1)t(1;1)(p36;q21) Acute myeloid leukemia, NOS    
1q21 der(1)t(1;1)(p36;q21) Diffuse large B-cell lymphoma    
1q21 der(1)t(1;1)(p36;q21) Follicular lymphoma   21   
1q21 der(1)t(1;1)(p36;q21) Nodal marginal zone B-cell lymphoma    
1q21 der(1)t(1;11)(q21;q23)t(1;11)(p12;q25)ins(1;11)(p32;q13q23) Acute myelomonocytic leukemia (FAB type M4)    
1q21 der(10)t(1;10)(q21;q22) Acute myeloid leukemia, NOS    
1q21 der(11)t(1;11)(q21;q14) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(11)t(1;11)(q21;q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(11)t(1;11)(q21;q23) Acute myeloid leukemia, NOS    
1q21 der(11)t(1;11)(q21;q23) Bilineage or biphenotypic leukemia    
1q21 der(11)t(1;11)(q21;q23) Myelodysplastic syndrome, NOS    
1q21 der(11)t(1;11)(q21;q23)del(11)(q13q23) Acute myelomonocytic leukemia (FAB type M4)    
1q21 der(12)t(1;12)(q21;q24) Follicular lymphoma    
1q21 der(12)t(1;12)(q21;q24) Multiple myeloma    
1q21 der(13)t(1;13)(q21;q14) Follicular lymphoma    
1q21 der(13)t(1;13)(q21;q32) Follicular lymphoma    
1q21 der(13)t(1;13)(q21;q34) Burkitt lymphoma/leukemia    
1q21 der(13)t(1;13)(q21;q34) Follicular lymphoma    
1q21 der(14)t(1;14)(q21;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(14)t(1;14)(q21;q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(14)t(1;14)(q21;q32) Burkitt lymphoma/leukemia    
1q21 der(14)t(1;14)(q21;q32) Diffuse large B-cell lymphoma    

Band Abnormality Morphology Topography Cases Genes
1q21 der(14)t(1;14)(q21;q32) Follicular lymphoma    
1q21 der(14)t(1;14)(q21;q32) Multiple myeloma    
1q21 der(15)t(1;15)(q21;p13) Diffuse large B-cell lymphoma    
1q21 der(15)t(1;15)(q21;q26) Multiple myeloma    
1q21 der(16)t(1;16)(q21;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(16)t(1;16)(q21;p13) Acute megakaryoblastic leukemia (FAB type M7)    
1q21 der(16)t(1;16)(q21;p13) Multiple myeloma    
1q21 der(16)t(1;16)(q21;q11) Multiple myeloma    
1q21 der(16)t(1;16)(q21;q12) Multiple myeloma    
1q21 der(16)t(1;16)(q21;q12) Wilms tumor Kidney  
1q21 der(16)t(1;16)(q21;q13) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(16)t(1;16)(q21;q13) Acute myeloid leukemia, NOS    
1q21 der(16)t(1;16)(q21;q13) Alveolar rhabdomyosarcoma Soft tissue  
1q21 der(16)t(1;16)(q21;q13) Ewing sarcoma Skeleton 11   
1q21 der(16)t(1;16)(q21;q13) Multiple myeloma    
1q21 der(16)t(1;16)(q21;q13) Wilms tumor Kidney 12   
1q21 der(16)t(1;16)(q21;q21) Diffuse large B-cell lymphoma    
1q21 der(16)t(1;16)(q21;q23) Wilms tumor Kidney  
1q21 der(16)t(1;16)(q21;q24) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(16)t(1;16)(q21;q24) Follicular lymphoma    
1q21 der(17)t(1;17)(q21;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(17)t(1;17)(q21;p11) Chronic myeloid leukemia, t(9;22)    
1q21 der(17)t(1;17)(q21;p13) Diffuse large B-cell lymphoma    
1q21 der(17)t(1;17)(q21;p13) Retinoblastoma Eye  
1q21 der(17)t(1;17)(q21;q25) Follicular lymphoma    
1q21 der(18)t(1;18)(q21;p11) Nodal marginal zone B-cell lymphoma    
1q21 der(18)t(1;18)(q21;q12) Follicular lymphoma    
1q21 der(18)t(1;18)(q21;q23) Burkitt lymphoma/leukemia    
1q21 der(18)t(1;18)(q21;q23) Follicular lymphoma    
1q21 der(19)t(1;19)(q21;p13) Acute lymphoblastic leukemia/lymphoblastic lymphoma   13   
1q21 der(19)t(1;19)(q21;p13) Acute myeloid leukemia, NOS    
1q21 der(19)t(1;19)(q21;p13) Chondrosarcoma, NOS Skeleton  
1q21 der(19)t(1;19)(q21;q13) Multiple myeloma    
1q21 der(2)t(1;2)(q21;p25) Follicular lymphoma    
1q21 der(2)t(1;2)(q21;q33) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(20)t(1;20)(q21;p13) Multiple myeloma    
1q21 der(20)t(1;20)(q21;q13) Burkitt lymphoma/leukemia    
1q21 der(21)t(1;21)(q21;p11) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(21)t(1;21)(q21;q22) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(22)t(1;22)(q21;p11) Diffuse large B-cell lymphoma    
1q21 der(22)t(1;22)(q21;q13) Diffuse large B-cell lymphoma    
1q21 der(3)t(1;3)(q21;p13) Adenocarcinoma Kidney  
1q21 der(3)t(1;3)(q21;p25) Multiple myeloma    
1q21 der(3)t(1;3)(q21;q27) Diffuse large B-cell lymphoma    
1q21 der(4)t(1;4)(q21;p16) Follicular lymphoma    
1q21 der(4)t(1;4)(q21;q35) Multiple myeloma    
1q21 der(5)t(1;5)(q21;p15) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(5)t(1;5)(q21;q35) Multiple myeloma    
1q21 der(6)t(1;6)(q21;q14) Burkitt lymphoma/leukemia    
1q21 der(6)t(1;6)(q21;q21) Diffuse large B-cell lymphoma    
1q21 der(6)t(1;6)(q21;q21) Multiple myeloma    
1q21 der(6)t(1;6)(q21;q23) Follicular lymphoma    
1q21 der(6)t(1;6)(q21;q27) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(7)t(1;7)(q21;q22) Acute myeloid leukemia, NOS    
1q21 der(7)t(1;7)(q21;q36) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 der(8)t(1;8)(q21;p11) Burkitt lymphoma/leukemia    
1q21 der(Y)t(Y;1)(q12;q21) Acute myeloblastic leukemia with maturation (FAB type M2)    
1q21 der(Y)t(Y;1)(q12;q21) Refractory anemia with excess blasts-2    
1q21 dup(1)(q11q21) Chronic myeloid leukemia, t(9;22)    
1q21 dup(1)(q21q21) Follicular lymphoma    
1q21 dup(1)(q21q21) Follicular lymphoma    
1q21 dup(1)(q21q23) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 dup(1)(q21q23) Follicular lymphoma    
1q21 dup(1)(q21q23) Mature B-cell neoplasm, NOS    
1q21 dup(1)(q21q24) Burkitt lymphoma/leukemia    
1q21 dup(1)(q21q25) Burkitt lymphoma/leukemia    
1q21 dup(1)(q21q25) Diffuse large B-cell lymphoma    
1q21 dup(1)(q21q25) Follicular lymphoma    
1q21 dup(1)(q21q31) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 dup(1)(q21q31) Burkitt lymphoma/leukemia   10   
1q21 dup(1)(q21q31) Chronic lymphocytic leukemia    
1q21 dup(1)(q21q31) Diffuse large B-cell lymphoma    
1q21 dup(1)(q21q31) Follicular lymphoma    
1q21 dup(1)(q21q31) Multiple myeloma    
1q21 dup(1)(q21q32) Acute lymphoblastic leukemia/lymphoblastic lymphoma   50   
1q21 dup(1)(q21q32) Acute myeloblastic leukemia with maturation (FAB type M2)    
1q21 dup(1)(q21q32) Acute myeloid leukemia, NOS    
1q21 dup(1)(q21q32) Adenocarcinoma Ovary  
1q21 dup(1)(q21q32) Adult T-cell lymphoma/leukemia (HTLV-1+)    
1q21 dup(1)(q21q32) Bilineage or biphenotypic leukemia    
1q21 dup(1)(q21q32) Burkitt lymphoma/leukemia   24   
1q21 dup(1)(q21q32) Diffuse large B-cell lymphoma   11   
1q21 dup(1)(q21q32) Follicular lymphoma    
1q21 dup(1)(q21q32) Idiopathic myelofibrosis    
1q21 dup(1)(q21q32) Mature B-cell neoplasm, NOS    
1q21 dup(1)(q21q32) Multiple myeloma    
1q21 dup(1)(q21q32) Myelodysplastic syndrome, NOS    
1q21 dup(1)(q21q32) Plasma cell leukemia    
1q21 dup(1)(q21q41) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1q21 dup(1)(q21q41) Burkitt lymphoma/leukemia    
1q21 dup(1)(q21q42) Acute lymphoblastic leukemia/lymphoblastic lymphoma   12   
1q21 dup(1)(q21q42) Acute myeloid leukemia, NOS    
1q21 dup(1)(q21q42) Adult T-cell lymphoma/leukemia (HTLV-1+)    
1q21 dup(1)(q21q42) Burkitt lymphoma/leukemia    
1q21 dup(1)(q21q42) Follicular lymphoma    
1q21 dup(1)(q21q42) Idiopathic myelofibrosis    
1q21 dup(1)(q21q42) Polycythemia vera    
1q21 dup(1)(q21q42) Refractory anemia    
1q21 dup(1)(q21q44) Acute lymphoblastic leukemia/lymphoblastic lymphoma   21   
1q21 dup(1)(q21q44) Acute myeloid leukemia, NOS    

Band Abnormality Morphology Topography Cases Genes
1q21 dup(1)(q21q44) Adenocarcinoma Breast  
1q21 dup(1)(q21q44) Anaplastic large cell lymphoma, systemic type    
1q21 dup(1)(q21q44) Burkitt lymphoma/leukemia    
1q21 dup(1)(q21q44) Chronic myeloid leukemia, t(9;22)    
1q21 dup(1)(q21q44) Diffuse large B-cell lymphoma    
1q21 dup(1)(q21q44) Follicular lymphoma    
1q21 dup(1)(q21q44) Mature B-cell neoplasm, NOS    
1q21 dup(1)(q21q44) Multiple myeloma    
1q21 dup(1)(q21q44) Polycythemia vera    
1q21 dup(1)(q31q21) Burkitt lymphoma/leukemia    
1q21 dup(1)(q31q21) Chronic myeloid leukemia, t(9;22)    
1q21 dup(1)(q32q21) Acute lymphoblastic leukemia/lymphoblastic lymphoma