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Cancer Genome Characterization Initiative

Visit the database of genomic characterization data for multiple tumor types.

The Recurrent Chromosome Aberrations in Cancer Database Searcher
  • Brief instructions for searching the database:
    • You must choose one or both of the following two fields: Structural Aberrations and Numerical Aberrations.
    • If you choose Structural Aberrations, you must select at least one of the following fields: Breakpoint, Topography, Morphology, or Gene.
    • If you choose Numerical Aberrations, you must select at least one of the following fields: Chromosome, Topography, Morphology.
    • You may select only one item in each pulldown menu
    • Press Retrieve.
  • A successful search returns a table, with the following headings and entries:
    • Breakpoint, with each entry linked to the OMIM Gene Map (this column is returned only for structural aberrations)
    • Abnormality
    • Morphology, with each entry linked to a similar table that describes all abnormalities with this morphology.
    • Topography, with each entry linked to a similar table that describes all abnormalities at this topography
    • Number of cases, hyperlinked to the list of applicable cases
    • Genes

Aberration type:
Aberration type:




Expand Topography List:

Expand Morphology List:

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[Full Text]

Balanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p35 t(1;12)(p35;q12) Subungual exostosis Skeleton  
1p35 t(1;6)(p35;p25) Chronic lymphocytic leukemia    
1p35 t(1;9;22)(p35;q34;q11) Chronic myeloid leukemia, aberrant translocation   BCR/ABL1

Unbalanced Chromosomal Abnormalities

Band Abnormality Morphology Topography Cases Genes
1p35 add(1)(p35) Acute lymphoblastic leukemia/lymphoblastic lymphoma    
1p35 add(1)(p35) Acute myeloblastic leukemia with maturation (FAB type M2)    
1p35 add(1)(p35) Adenocarcinoma Breast  
1p35 add(1)(p35) Adult T-cell lymphoma/leukemia (HTLV-1+)    
1p35 add(1)(p35) Diffuse large B-cell lymphoma    
1p35 add(1)(p35) Malignant peripheral nerve sheath tumor/Triton Soft tissue  
1p35 add(1)(p35) Retinoblastoma Eye  
1p35 del(1)(p12p35) Multiple myeloma    
1p35 del(1)(p22p35) Multiple myeloma    
1p35 del(1)(p35) Adenocarcinoma Ovary  
1p35 del(1)(p35) Diffuse large B-cell lymphoma    
1p35 del(1)(p35) Follicular lymphoma    
1p35 del(1)(p35) Teratoma (mature and immature) Testis  
1p35 der(1)t(1;2)(p35;p21) Adenoma Salivary gland